Special Online Collection: Metabolism

Special Online Collection: Metabolism

In the 3 December 2010 issue, Science celebrates a resurgence of interest in metabolism and its central role in disparate areas of cell biology, physiology, medicine, and synthetic biology. An opening Perspective takes a broad look at the field, while Review articles examine the links between metabolism and cancer, autophagy, circadian clocks, and molecular engineering. A Focus Issue of Science Signaling highlights signaling pathways with roles in metabolism and a Review in Science Translational Medicine discusses a possible therapeutic target for metabolic disease.

In Science


Metabolism Is Not Boring
L. Bryan Ray


On Getting There from Here
S. L. McKnight

In Science Signaling


Research Articles

A Kinase-Independent Role for Unoccupied Insulin and IGF-1 Receptors in the Control of Apoptosis
J. Boucher et al.
» See the related Perspective by P. Mehlen
Regulation of the 26S Proteasome Complex During Oxidative Stress
X. Wang et al.
» Listen to the related Podcast with L. Huang and A.M. VanHook

In Science Translational Medicine


The Role of JNK Proteins in Metabolism
S. N. Vallerie and G. S. Hotamisligil