Special Issue | 11 July 2014Strategies against HIV/AIDS

INTRODUCTIONScience's special section on HIV/AIDS focuses on the success of Australia's approach to combating HIV and its neighbors’ (Malaysia, Indonesia, and Papua New Guinea) efforts emulating some of Australia's methods to stem their own epidemics. However, critical issues remain unresolved about how to develop even more effective responses against HIV than now exist. [Read the full introduction.]

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Science Video

Harm reduction

Australia's successful efforts to slow the spread of HIV/AIDS has made the country a model for its neighbors.

First, do harm reduction

Australia's aggressive efforts to stop HIV's spread via injecting drugs averted a catastrophe.

The limits of success

Increasing prevalence in Australia's men who have sex with men raises questions about treatment as prevention.

In PNG, the epidemic that wasn’t

Data vacuum despite improved surveillance.

Prevention, Papua New Guinea style

A community gathers to watch a video about HIV's impact on a local family and meet the star.

The circumcision conundrum

No clear mechanism explains how removing a foreskin protects men from HIV, but traditional penile cutting in Papua New Guinea may help clarify.

A consummate insider pushes ideas from outside Indonesia

Sex and drugs rock Health Minister Mboi's reign.

Malaysia tries to follow Australia’s path

A top researcher and advocate pushes for change.

End of AIDS—hype versus hope

Rethinking the rallying cry.

A critical question for HIV vaccine development: Which antibodies to induce?

Researchers should pursue vaccine strategies that elicit potent, broadly neutralizing antibodies and less potent and less broad conventional antibodies.

Immunologic strategies for HIV-1 remission and eradication

Therapies that target the immune system may one day help eradicate the latent viral reservoir and cure HIV infected individuals.
News Graphic

HIV/AIDS in Australia and its neighbors

Diverse demographics and widely different responses shape unique epidemics in each country.

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Also in this special issue


Persistence driven by proliferation?

Latently HIV-infected cells driven to proliferate may raise a further challenge for eradication strategies.

A fitness bottleneck in HIV-1 transmission

A successful infection is determined in part by how close a viral genome is to an ideal sequence.

Hepatitis C can be cured globally, but at what cost?

Lessons learned from reducing the cost of HIV therapies could be applied to HCV treatments.
Science Video

Traditional circumcision in PNG

Researchers are investigating traditional circumcision practices in Papua New Guinea in an attempt to help reduce the spread of HIV.

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