Forces in Development

INTRODUCTION—When gazing at the stages from embryo to adult, it is clear that a multitude of cell movements and deformations are at play to shape the folds, cavities, and appendages. How do these dynamic activities come about? [Read the full introduction]


From Science

Review

Developmental Pattern Formation: Insights from Physics and Biology

A. Kicheva et al.
Dynamic interactions between morphogens and gene regulatory networks determine cell fate and tissue patterning.
Review

Knowing the Boundaries: Extending the Differential Adhesion Hypothesis in Embryonic Cell Sorting

J. D. Amack and M. L. Manning
Mechanobiology is applied to developmental biology to understand forces controlling cell sorting and compartmentalization.
Perspective

A Dynamical-Systems View of Stem Cell Biology

C. Furusawa and K. Kaneko
A theoretic perspective can be used to describe stem cell behavior.
Perspective

Physico-Genetic Determinants in the Evolution of Development

S. A. Newman
Physical processes mobilized by ancient genes in a multicellular context established animal form.
 
 
See Also
Report
Adhesion Functions in Cell Sorting by Mechanically Coupling the Cortices of Adhering Cells
J.-L. Maître et al.
Report
Forces Driving Epithelial Spreading in Zebrafish Gastrulation
M. Behrndt et al.
Research Article
Cilia at the Node of Mouse Embryos Sense Fluid Flow for Left-Right Determination via Pkd2
S. Yoshiba et al.
Editorial
Enabling Scientific Innovation
J. S. Langer
Perspective
Physical Biology Returns to Morphogenesis
R. Keller
Perspective
Cilia Discern Left from Right
D. P. Norris and D. T. Grimes
Podcast | FREE ACCESS
Special Segment
Listen to an interview with special issue contributor Stuart Newman.

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[Cover image credit: Dr. Richard Kessel/Visuals Unlimited, Inc.; header image credit: Martin Behrndt, Stephan Grill and Carl-Philipp Heisenberg.]