Special CollectionDrugs against infectious diseases

Linda M. Stannard/Univ. of Cape Town/Science Source/Photo Researchers


Infectious diseases are rarely out of the headlines, from the recent Ebola outbreak in Africa and the spread of bird flu to high-profile initiatives aiming to counter the threat of antibiotic resistance. Yet, few new drugs for treating infectious diseases are coming to market, particularly against the neglected diseases that mainly affect lower-income countries. This series of Perspectives looks at some of the reasons behind the faltering drug pipeline and identifies ways of bolstering research and development of antibiotic, antifungal, antiviral, and antiparasitic drugs.

29 May 2015 | Perspective

Overcoming neglect of kinetoplastid diseases

Drug development offers hope for controlling diseases that affect millions of people worldwide.
8 May 2015 | Perspective

More than just bugs in spit

Advances in imaging help to explain tuberculosis treatment failures and develop better drugs.
17 April 2015 | Perspective

Combating emerging viral threats

Broad-spectrum antiviral drugs are under development to treat emerging viral diseases such as Ebola and dengue for which no specific, licensed treatments exist.
27 March 2015 | Perspective

How to bolster the antifungal pipeline

Few drugs are coming to market, but opportunities for drug development exist.
6 March 2015 | Perspective

A return to the pre-antimicrobial era?

The effects of antimicrobial resistance will be felt most acutely in lower-income countries.
6 March 2015 | Perspective

A sustainable model for antibiotics

How can we foster the development of novel drugs against resistant bacteria?

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