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From genomic biomarkers to multiomics: Next-generation sequencing in cancer research

Actionable genomic biomarker research is on the rise. These indicators, which include patterns of gene expression or DNA changes, facilitate development of cancer patient treatments by enhancing disease diagnosis and prognosis as well as tracking therapy efficacy. Multiomic analyses, combining methods including whole exome/genome sequencing (WES/WGS), transcriptome sequencing, human leukocyte antigen (HLA) typing, and single-cell sequencing, hold promise to identify actionable genomic biomarkers of the future.

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