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Vote for your scientific breakthrough of the year winner!

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The last few weeks of 2015 are upon us—the season of holidays, shopping lists, and end-of-the-year retrospectives. Here at Science, in keeping with tradition, our news writers and editors are getting ready to unveil the 20th “Breakthrough of the Year”: their choice of most momentous scientific discovery, development, or trend of 2015, to be announced when the last issue of the year goes online on 17 December.

But there’s no need to wait—you can get in on the action now. Our top 10 finalists are listed below. Pick your favorite and send in your vote. We’ll tally the results and report the top-place finisher as our “People’s Choice” award, along with the editors’ pick. Check back for running totals, and see how your choice stacks up against ours.