SITC 2019 Special Collection of Free Articles from Science Immunology

Welcome to the Special Collections page for Science Immunology. This new Special Collection with a theme of “Cancer Immunotherapy” was assembled for the 2019 meeting of the Society for Immunotherapy of Cancer meeting in National Harbor, Maryland. The collection features nine research articles published in 2018 and 2019. These articles cover multiple cancer immunotherapy topics within the scope of Science Immunology including checkpoint blockade, neoantigen identification, combined modality tumor therapy and myeloid-derived suppressor cells.

Ifor Williams, Editor of Science Immunology, will be attending the SITC 2019 meeting from November 6-10. If you are interested in meeting with the Editor at SITC 2019, please reach out to him directly by email. He is available for conversations with interested authors during the meeting.

Please consider submitting your best work on cancer immunotherapy to Science Immunology.

Research Articles

Combination cancer immunotherapy targeting PD-1 and GITR can rescue CD8+ T cell dysfunction and maintain memory phenotype

By Bei Wang, Wen Zhang, Vladimir Jankovic, Jacquelynn Golubov, Patrick Poon, Erin M. Oswald, Cagan Gurer, Joyce Wei, Ilyssa Ramos, Qi Wu, Janelle Waite, Min Ni, Christina Adler, Yi Wei, Lynn Macdonald, Tracey Rowlands, Susannah Brydges, Jean Siao, William Poueymirou, Douglas Macdonald, George D. Yancopoulos, Matthew A. Sleeman, Andrew J. Murphy, Dimitris Skokos
Science Immunology | Vol 3 Iss 29

Impaired enolase 1 glycolytic activity restrains effector functions of tumor-infiltrating CD8+ T cells

By Lelisa F. Gemta, Peter J. Siska, Marin E. Nelson, Xia Gao, Xiaojing Liu, Jason W. Locasale, Hideo Yagita, Craig L. Slingluff, Jr., Kyle L. Hoehn, Jeffrey C. Rathmell, Timothy N. J. Bullock
Science Immunology | Vol 4 Iss 31

Tumor-infiltrating human CD4+ regulatory T cells display a distinct TCR repertoire and exhibit tumor and neoantigen reactivity

By Mojgan Ahmadzadeh, Anna Pasetto, Li Jia, Drew C. Deniger, Sanja Stevanović, Paul F. Robbins, Steven A. Rosenberg
Science Immunology  | Vol 4 Iss 31

Intratumoral activation of the necroptotic pathway components RIPK1 and RIPK3 potentiates antitumor immunity

By Annelise G. Snyder, Nicholas W. Hubbard, Michelle N. Messmer, Sigal B. Kofman, Cassidy E. Hagan, Susana L. Orozco, Kristy Chiang, Brian P. Daniels, David Baker, Andrew Oberst
Science Immunology | Vol 4 Iss 36

Engineering nanoparticles to locally activate T cells in the tumor microenvironment

By Dangge Wang, Tingting Wang, Haijun Yu, Bing Feng, Lei Zhou, Fangyuan Zhou, Bo Hou, Hanwu Zhang, Min Luo, Yaping Li
Science Immunology | Vol 4 Iss 37

Hypofractionated EGFR tyrosine kinase inhibitor limits tumor relapse through triggering innate and adaptive immunity

By Zhida Liu, Chuanhui Han, Chunbo Dong, Aijun Shen, Eric Hsu, Zhenhua Ren, Changzheng Lu, Longchao Liu, Anli Zhang, Casey Timmerman, Yang Pu, Yang Wang, Mingyi Chen, Jian Qiao, Yang-Xin Fu
Science Immunology | Vol 4 Iss 38

Myeloid cell–synthesized coagulation factor X dampens antitumor immunity

By Claudine Graf, Petra Wilgenbus, Sven Pagel, Jennifer Pott, Federico Marini, Sabine Reyda, Maki Kitano, Stephan Macher-Göppinger, Hartmut Weiler, Wolfram Ruf
Science Immunology | Vol 4 Iss 39

RIG-I activation is critical for responsiveness to checkpoint blockade

By Simon Heidegger, Alexander Wintges, Florian Stritzke, Sarah Bek, Katja Steiger, Paul-Albert Koenig, Sascha Göttert, Thomas Engleitner, Rupert Öllinger, Tatiana Nedelko, Julius C. Fischer, Vladimir Makarov, Christof Winter, Roland Rad, Marcel R.M. Van Den Brink, Jürgen Ruland, Florian Bassermann, Timothy A. Chan, Tobias Haas, Hendrik Poeck
Science Immunology | Vol 4 Iss 39

Multidimensional imaging provides evidence for down-regulation of T cell effector function by MDSC in human cancer tissue

By Yu Si, Simon F. Merz, Philipp Jansen, Baoxiao Wang, Kirsten Bruderek, Petra Altenhoff, Stefan Mattheis, Stephan Lang, Matthias Gunzer, Joachim Klode, Anthony Squire, Sven Brandau
Science Immunology | Vol 4 Iss 40

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Special edition booklets

Download our FREE special edition booklets. These special edition booklets contain a collection of research articles from the Science Family of Journals.