The maintenance of telomeres—the structures of repetitive sequences at the end of a chromatid—is essential to the health of a cell. Dysfunction in telomere maintenance pathways plays an integral role in aging, cancer, and certain rare diseases such as dyskeratosis congenita (DC). The molecular analysis of telomere length, telomerase levels, and activation of the Alternative Lengthening of Telomeres (ALT) pathway are currently being used as prognostic tools in human diseases. This has led to telomere maintenance as a prime target for patient therapies. Studies have shown the modification of TERC (TElomerase RNA Component) expression may be therapeutically beneficial in DC patients. Additionally, current research is targeting telomere lengthening mechanisms as a cancer therapy. In this webinar, our experts will describe the advances in telomere research as it applies to human health and how deeper characterization of the telomerase maintenance process can uncover targets for therapies.
During the webinar, speakers will discuss:
- Genetic and molecular processes underlying telomere diseases such as cancer and dyskeratosis congenita
- Detection of Alternative Lengthening of Telomeres pathways and telomerase activity in tumor cells
- Prognostic significance of telomere biology and its impact on patient care
- Approaches to targeting telomere lengthening mechanisms
- Answers to your questions, live!
For product or technologies related to this webinar, go to: www.perkinelmer.com/P32
Webinar Extra Q&A Podcast
Listen to this podcast to hear our expert speakers answer additional audience questions.