Virus transduction is a common and powerful nucleic-acid delivery tool used by researchers in both the academic and private sector for numerous molecular and cell biology applications. Adeno-associated viruses (AAV) and lentiviruses are also becoming the preferred viral vector systems for gene delivery in clinical trials because of their ability to infect a variety of cell types with high efficiency for sustained gene expression or for cell-line engineering applications. Yet, these virus vectors have several shortcomings, including elaborate and labor-intensive production procedures, low packaging capacities, and variable infection rates. In addition, there is a need for current good manufacturing practices (cGMP) ancillary materials in clinical trials for production of high-quality, high-titer viruses. Effective solutions are now available to address these needs for research and biotherapeutic workflows.
During the webinar, the speakers will:
- Discuss the benefits of virus-mediated delivery
- Introduce applications supported by AAV/lentiviruses
- Describe recent advances in virus production
- Answer your questions during the live broadcast!
This webinar will last for approximately 60 minutes.