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Monitoring the immune system to fight COVID-19: Investigating lymphocyte subsets as surrogate biomarkers to prioritize patient care

This webinar is brought to you by the Science/AAAS Custom Publishing Office

Monitoring the immune system to fight COVID-19: Investigating lymphocyte subsets as surrogate biomarkers to prioritize patient care

03 February 2021

12:00 p.m. ET

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As the COVID-19 pandemic continues its global impact into 2021, what we have learned in 2020 is being leveraged to optimize patient care and prioritize precious resources. In this webinar, we continue the conversation from Part 1 of this topic, presenting additional data from a study using flow cytometry data to explore the role of T-cell subtypes as a surrogate biomarker to elucidate risk, disease severity, and clinical outcomes for patients with COVID-19. The speakers are experts and global leaders in cytometry and infectious disease who have been working on the frontlines of the COVID-19 outbreaks in the United States, United Kingdom, and Europe. They will provide concrete examples of how flow cytometry has been harnessed to provide key laboratory evidence that can help clinicians prioritize limited resources in the fight against SARS-CoV-2 and COVID-19.

During the webinar, the speakers will:

  • Describe how immune profiling using flow cytometry is revealing surrogate biomarkers for clinical outcomes of COVID-19
  • Provide examples of how results at the bench might be translated to the clinic to impact patient care
  • Outline how deeper immune profiling of lymphocyte subsets might inform better patient treatment in the future
  • Answer your questions during the live broadcast.

You can also watch part 1 of this series.

This webinar will last for approximately 60 minutes.

Speaker bios

Francesco Buccisano, M.D.

University of Rome Tor Vergata
Rome, Italy

Dr. Buccisano is an associate professor of hematology in the Department of Biomedicine and Prevention at the University of Rome Tor Vergata, where he leads the Molecular Treatment of Acute Leukemia Program and the flow cytometry section of the Hematology Laboratory. His research focuses on diseases such as acute myeloid leukemia, myelodysplastic syndromes, and immune thrombocytopenia, as well as the development of innovative techniques for monitoring and analysis of minimal residual disease in acute myeloid leukemia and other hematological malignancies. Dr. Buccisano is president of the Italian Society for Cytometric Cell Analysis, a member of the European LeukemiaNet Minimal Residual Disease Working Party, a board member of the European Society for Clinical Cell Analysis (ESCCA), and secretary of the Acute Leukemia Working Party of the Gruppo Italiano Malattie Ematologiche Maligne dell’Adulto (GIMEMA). He has authored over 120 publications in peer-reviewed journals and has a personal H-index of 32 (as of November 2020).

Marco Iannetta, M.D., Ph.D.

University of Rome Tor Vergata
Rome, Italy

Dr. Iannetta is an infectious disease specialist and faculty member in the Department of Systems Medicine at the University of Rome Tor Vergata. His clinical and research activities are mainly focused on the host–pathogen interaction and the immunopathogenesis of viral and bacterial infections. He is an expert in flow cytometry and its clinical application to infectious diseases. He received his medical degree from the Medical School of Sapienza University of Rome, Italy, where he completed a residency in infectious disease and obtained his Ph.D. in immunology. Dr. Iannetta completed a postdoctoral fellowship investigating the immunopathogenesis of HIV-1 and HIV-2 infection with the Dendritic Cell Biology Team of INSERM’s Department of Infection, Immunity and Inflammation in Paris, France. He also worked in the Lazzaro Spallanzani National Institute for Infectious Diseases (INMI) in Rome, Italy, conducting clinical and research activities on emerging and reemerging infectious diseases.

Maurice O’Gorman, Ph.D., M.B.A., (D)ABMLI

Children's Hospital Los Angeles and USC,
Los Angeles, CA

Dr. O’Gorman earned his Master’s and Ph.D. at the University of British Columbia before completing a postdoctoral fellowship at the University of North Carolina at Chapel Hill. He spent the next 21 years as a professor of Pathology and Pediatrics at the Feinberg School of Medicine at Northwestern University, during which time he earned his MBA from Northwestern’s Kellogg School of Management and served as vice chair of Pathology and Laboratory Medicine and director of Diagnostic Immunology and Flow Cytometry at Children’s Memorial Hospital in Chicago. He is currently chief of laboratory medicine, as well as director of the Clinical Lab and the Diagnostic Immunology and Flow Cytometry Laboratory at Children’s Hospital Los Angeles, and a professor of pathology and pediatrics at the Keck School of Medicine of the University of Southern California. Dr. O’Gorman’s research interests include the discovery of biomarkers related to the immunopathogenesis of immune system–related disorders and the development of diagnostic laboratory tests for the latter. Additionally, he has written over one hundred peer-reviewed publications and several book chapters, served as president of the Association of Medical Laboratory Immunologists, and held numerous other leadership positions. 

Sean Sanders, Ph.D.

Washington, DC

Dr. Sanders did his undergraduate training at the University of Cape Town, South Africa, and his Ph.D. at the University of Cambridge, UK, supported by the Wellcome Trust. Following postdoctoral training at the National Institutes of Health and Georgetown University, Dr. Sanders joined TranXenoGen, a startup biotechnology company in Massachusetts working on avian transgenics. Pursuing his parallel passion for writing and editing, Dr. Sanders joined BioTechniques as an editor, before joining Science/AAAS in 2006. Currently, Dr. Sanders is the Director and Senior Editor for Custom Publishing for the journal Science and Program Director for Outreach.

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