According to conventional thinking, metabolic changes related to disease are thought to be triggered predominantly by signals from the immune cell-signaling network. However, recent evidence supports a role for metabolism as a “first responder” that can be decisive in actually forming immune responses and determining outcomes based on the metabolic potential and fitness of the responding cells. This new insight has led to the potential for reprogramming cellular metabolism to direct immune cell fate and function and thus to ultimately improve disease outcomes. In this webinar we will explain how metabolic pathways and substrates have been found to impact particular immune cell subsets and their functional roles. The application of this knowledge to better understand disease and to reveal novel therapeutic approaches will also be discussed.
During the webinar, our expert speakers will:
- Describe the metabolic pathways and substrates that control immune cell activation, amplification, effector function, and memory
- Demonstrate how the metabolic programs of immune cells are connected with their ability to respond to infection and disease
- Outline new therapeutic strategies that exploit the regulatory role of metabolism in immunity
- Answer your questions live during the broadcast!
The webinar will last approximately 60 minutes.