The ability to simultaneously interrogate protein and mRNA information in thousands of single cells is a recent development allowing greater insight into the biology of different disease states. Combined measurement of specific proteins and gene transcripts in individual cells is critical for understanding the role of cellular diversity in development, health, and disease, leading to more accurate insights into complex biological systems. These powerful tools allow researchers to gain a more comprehensive understanding of the intricacies of immune-related diseases, thus providing opportunities for more personalized treatments.
During this webinar, our expert speaker will describe how the power of multiomic single-cell analysis was applied in recent asthma research, in which thousands of T cells were captured using oligo-conjugated cell-surface antibodies and interrogated using targeted sequencing to identify immune-cell biomarkers. A digital gene-expression profile of thousands of individual cells was generated in a single experiment, without the need for robotics or automation, enabling identification of distinct cell-surface proteins and hundreds of gene-expression biomarkers.
In the webinar, viewers will:
- Learn about single-cell analysis methods based on RNA sequencing (RNAseq) and antibody oligonucleotide conjugates (AbSeq) technologies
- Understand the advantages of combining data from transcriptomics and proteomics analysis
- Gain insight into how single-cell multiomic methods can be applied to identify biomarkers and cell subsets using asthma as a model
- Be able to ask questions during the live broadcast.
This webinar will last for approximately 60 minutes.