Research in the field of epigenetics has exploded in the last several years, as evidenced by the rapidly expanding volume of published literature. Significant advances have been made in the illumination of basic epigenetic mechanisms such as chromatin remodeling, DNA methylation, and RNA signaling. With these advances has also come an understanding of the critical roles that epigenetic modifications play in the development and progression of disease, and an increased focus on the identification of clinical treatments for aberrant epigenetic states. Given the increasing interest and investment in drug discovery for epigenetic targets, there is a clear need for robust methodologies to identify candidate therapeutic compounds. This webinar will focus on novel techniques for drug discovery against histone-modifying enzymes.
During this webinar, our panelists will:
- Briefly cover the basics of epigenetic modifications and how they impact gene expression and disease states
- Discuss current techniques for identifying and validating potential targets for clinical intervention
- Share their personal experience working with histone-modifying enzymes as therapeutic targets.
- Answer your questions live during the broadcast!
For related product/technology information, go to: www.perkinelmer.com/epigenetics