Thermo Fisher Scientific
The Covaris M220 Focused-ultrasonicator is designed for NGS applications that require high-quality DNA fragmentation for library preparation. It efficiently focuses the minimum amount of energy required directly into a sample, enabling precise control of the hydrodynamic shearing forces that fragment nucleic acids to the selected size. The process is isothermal, so fragmentation is unbiased, the sample is undamaged, and yields are high. Covaris focused-ultrasonic technology is considered a DNA-shearing standard in many labs worldwide.