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Unlocking Alzheimer's mysteries: Deciphering the pathways to neurodegeneration

With the predicted worldwide incidence of Alzheimer's disease growing to over 130 million by 2050 and the cost of treatment and long-term care for these patients in the hundreds of billions of dollars, it is clear that we need better diagnosis, more treatment choices, and improved disease management options. In this supplement we have collected four important articles published in the Science family of journals that provide a sampling of the current research into different aspects of AD.  These papers exemplify the breadth of active research in this area, including neuroinflammation, mouse model systems for uncovering disease pathways, and the possible involvement of microbes in neurodegenerative disease. Add to this two informative white papers and an enlightening interview with preeminent Alzhemier's researcher, Dr. Beth Stevens, and you have a wonderful educational primer on this important and exciting area of investigation.

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