Electron microscope image of SARS-CoV-2 (orange).

National Institute of Allergy and Infectious Diseases

Coronavirus: Research, Commentary, and News

The Science journals are striving to provide the best and most timely research, analysis, and news coverage of COVID-19 and the coronavirus that causes it. All content is free to access.

News

Science's COVID-19 reporting is supported by the Pulitzer Center.

Highlighted story: COVID-19 vaccine protects monkeys from new coronavirus, Chinese biotech reports

Antibody surveys suggesting vast undercount of coronavirus infections may be unreliable

Antimalarials widely used against COVID-19 heighten risk of cardiac arrest. How can doctors minimize the danger?

How does coronavirus kill? Clinicians trace a ferocious rampage through the body, from brain to toes

Visit News from Science for more coronavirus coverage (or use our COVID-19 RSS news feed).

Research and Commentary

Holden Thorp (Editor-in-Chief), Science: Valda Vinson (Editor, Research), Lisa Chong (Editor, Insights), Caroline Ash (Infectious diseases editor)

Mobile phone data for informing public health actions across the COVID-19 pandemic lifecycle
Nuria Oliver, Bruno Lepri, Harald Sterly, Renaud Lambiotte, Sébastien Delataille, Marco De Nadai, Emmanuel Letouzé, Albert Ali Salah, Richard Benjamins, Ciro Cattuto, Vittoria Colizza, Nicolas de Cordes, Samuel P. Fraiberger, Til Koebe, Sune Lehmann, Juan Murillo, Alex Pentland, Phuong N. Pham, Frédéric Pivetta, Jari Saramaki, Samuel V. Scarpino, Michele Tizzoni, Stefaan Vehulst, Patrick Vinck
Editorial | Science Advances Date: 27-Apr-2020 DOI: 10.1126/sciadv.abc0764

Squalene-based multidrug nanoparticles for improved mitigation of uncontrolled inflammation
Flavio Dormont et al.
Research Article | Science Advances Date: 27-Apr-2020 DOI: 10.1126/sciadv.aaz5466

Modeling infectious disease dynamics
Sarah Cobey
Perspective | Science Date: 24-Apr-2020 DOI: 10.1126/science.abb5659

Lost in transition
Kathleen Newland
Editorial | Science Date: 24-Apr-2020 DOI: 10.1126/science.abc3197

Against pandemic research exceptionalism
Alex John London, Jonathan Kimmelman
Policy Forum | Science Date: 23-Apr-2020 DOI: 10.1126/science.abc1731

Structure-b​ased design of antiviral drug candidates targeting the SARS-CoV-2 main protease
W. Dai et al.
Research Article | Science Date: 22-Apr-2020 DOI: 10.1126/science.abb4489

Medicine in the time of corona:  Fundamental molecular research is “essential”
Ali Shilatifard
Editorial | Science Advances Date: 21-Apr-2020 DOI: 10.1126/sciadv.abc2800

Why WHO?
H. Holden Thorp
Editorial | Science Date: 20-Apr-2020 DOI: 10.1126/science.abc3400

Surviving COVID-19: A disease tolerance perspective
Janelle S. Ayres
Editorial | Science Advances Date: 17-Apr-2020 DOI: 10.1126/sciadv.abc1518

Comparative pathogenesis of COVID-19, MERS and SARS in a non-human primate model
Barry Rockx et al.
Report | Science Date: 17-Apr-2020 DOI: 10.1126/science.abb7314

Cytokine release syndrome in severe COVID-19
John B. Moore, Carl H. June
Perspective | Science Date: 17-Apr-2020 DOI: 10.1126/science.abb8925

The moment to see the poor
Joachim von Braun, Stefano Zamagni, Marcelo Sánchez Sorondo
Editorial | Science Date: 17-Apr-2020 DOI: 10.1126/science.abc2255

Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period
Stephen M. Kissler, Christine Tedijanto, Edward Goldstein, Yonatan H. Grad, Marc Lipsitch
Report | Science Date: 14-Apr-2020 DOI: 10.1126/science.abb5793

Structure of the RNA-dependent RNA polymerase from COVID-19 virus
Yan Gao et al.
Report | Science Date: 10-Apr-2020 DOI: 10.1126/science.abb7498

G20 leaders must answer to COVID-19
Caroline Atkinson
Editorial | Science Date: 10-Apr-2020 DOI: 10.1126/science.abc1025

Effective containment explains sub-exponential growth in recent confirmed COVID-19 cases in China 
Benjamin F. Maier, Dirk Brockmann
Research Article | Science Date: 8-Apr-2020 DOI: 10.1126/science.abb4557

Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS-coronavirus-2 
Jianzhong Shi et al.
Report | Science Date: 8-Apr-2020 DOI: 10.1126/science.abb7015

An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice
Timothy P. Sheahan, Amy C. Sims, Shuntai Zho, Rachel L. Graham, Andrea J. Pruijssers, Maria L. Agostini, Sarah R. Leist, Alexandra Schäfer, Kenneth H. Dinnon III, Laura J. Stevens, James D. Chappell, Xiaotao Lu, Tia M. Hughes, Amelia S. George, Collin S. Hill, Stephanie A. Montgomery, Ariane J. Brown, Gregory R. Bluemling, Michael G. Natchus, Manohar Saindane, Alexander A. Kolykhalov, George Painter, Jennifer Harcourt, Azaibi Tamin, Natalie J. Thornburg, Ronald Swanstrom, Mark R. Denison, Ralph S. Baric
Research Article | Science Translational Medicine Date: 6-Apr-2020 DOI: 10.1126/scitranslmed.abb5883

A highly conserved cryptic epitope in the receptor-binding domains of SARS-CoV-2 and SARS-CoV
Meng Yuan, Nicholas C. Wu, Xueyong Zhu, Chang-Chun D. Lee, Ray T. Y. So, Huibin Lv, Chris K. P. Mok, Ian A. Wilson
Report | Science Date: 3-Apr-2020 DOI: 10.1126/science.abb7269

Quantifying SARS-CoV-2 transmission suggests epidemic control with digital contact tracing
Luca Ferretti, Chris Wymant, Michelle Kendall, Lele Zhao, Anel Nurtay, Lucie Abeler-Dörner, Michael Parker, David Bonsall, Christophe Fraser
Research Article | Science Date: 31-Mar-2020 DOI: 10.1126/science.abb6936

An investigation of transmission control measures during the first 50 days of the COVID-19 epidemic in China
Huaiyu Tian, Yonghong Liu, Yidan Li, Chieh-Hsi Wu, Bin Chen, Moritz U. G. Kraemer, Bingying Li, Jun Cai, Bo Xu, Qiqi Yang, Ben Wang, Peng Yang, Yujun Cui, Yimeng Song, Pai Zheng, Quanyi Wang, Ottar N. Bjornstad, Ruifu Yang, Bryan T. Grenfell, Oliver G. Pybus, Christopher Dye
Report | Science Date: 31-Mar-2020 DOI: 10.1126/science.abb6105

This is real
H. Holden Thorp
Editorial | Science Date: 27-Mar-2020 DOI: 10.1126/science.abb9223

COVID-19 needs a big science approach
Seth Berkley
Editorial | Science Date: 25-Mar-2020 DOI: 10.1126/science.abb8654

The effect of human mobility and control measures on the COVID-19 epidemic in China
Moritz U. G. Kraemer, Chia-Hung Yang, Bernardo Gutierrez, Chieh-Hsi Wu, Brennan Klein, David M. Pigott, Open COVID-19 Data Working Group, Louis du Plessis, Nuno R. Faria, Ruoran Li, William P. Hanage, John S. Brownstein, Maylis Layan, Alessandro Vespignani, Huaiyu Tian, Christopher Dye, Oliver G. Pybus, Samuel V. Scarpino
Research Article | Science Date: 25-Mar-2020 DOI: 10.1126/science.abb4218

Combating COVID-19—The role of robotics in managing public health and infectious diseases
Guang-Zhong Yang, Bradley J. Nelson, Robin R. Murphy, Howie Choset, Henrik Christensen, Steven H. Collins, Paolo Dario, Ken Goldberg, Koji Ikuta, Neil Jacobstein, Danica Kragic, Russell H. Taylor, Marcia McNutt
Editorial | Science Robotics Date: 25-Mar-2020 DOI: 10.1126/scirobotics.abb5589

Underpromise, overdeliver
H. Holden Thorp
Editorial | Science Date: 23-Mar-2020 DOI: 10.1126/science.abb8492

Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors
Linlin Zhang, Daizong Lin, Xinyuanyuan Sun, Ute Curth, Christian Drosten, Lucie Sauerhering, Stephan Becker, Katharina Rox, Rolf Hilgenfeld
Report | Science Date: 20-Mar-2020 DOI: 10.1126/science.abb3405

Time to pull together
H. Holden Thorp
Editorial | Science Date: 16-Mar-2020 DOI: 10.1126/science.abb7518

Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV2)
Ruiyun Li, Sen Pei, Bin Chen, Yimeng Song, Tao Zhang, Wan Yang, Jeffrey Shaman
Research Article | Science Date: 16-Mar-2020 DOI: 10.1126/science.abb3221 

Do us a favor
H. Holden Thorp
Editorial | Science Date: 11-Mar-2020 DOI: 10.1126/science.abb6502

New coronavirus outbreak: Framing questions for pandemic prevention
Scott P. Layne, James M. Hyman, David M. Morens, Jeffrey K. Taubenberger
Editorial | Science Translational Medicine Date: 11-Mar-2020 DOI: 10.1126/scitranslmed.abb1469

The effect of travel restrictions on the spread of the 2019 novel coronavirus (COVID-19) outbreak
Matteo Chinazzi, Jessica T. Davis, Marco Ajelli, Corrado Gioannini, Maria Litvinova, Stefano Merler, Ana Pastore y Piontti, Kunpeng Mu, Luca Rossi, Kaiyuan Sun, Cécile Viboud, Xinyue Xiong, Hongjie Yu, M. Elizabeth Halloran, Ira M. Longini Jr., Alessandro Vespignani
Research Article | Science Date: 6-Mar-2020 DOI: 10.1126/science.aba9757

Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2
Renhong YanYuanyuan ZhangYaning LiLu XiaYingying GuoQiang Zhou
Research Article | Science Date: 4-Mar-2020 DOI: 10.1126/science.abb2762

The costs of secrecy
H. Holden Thorp
Editorial | Science Date: 28-Feb-2020 DOI: 10.1126/science.abb4420

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
Daniel Wrapp, Nianshuang Wang, Kizzmekia S. Corbett, Jory A. Goldsmith, Ching-Lin Hsieh, Olubukola Abiona, Barney S. Graham, Jason S. McLellan
Report | Science Date: 19-Feb-2020 DOI: 10.1126/science.abb2507

Letters to the Editor

Protect Indigenous peoples from COVID-19
Lucas Ferrante, Philip M. Fearnside
Letter to the Editor | Science Date: 17-Apr-2020 DOI: 10.1126/science.abc0073

Protecting older adults during social distancing
Ali Jawaid
Letter to the Editor | Science Date: 10-Apr-2020 DOI: 10.1126/science.abb7885

Disinfection threatens aquatic ecosystems
Hong Zhang et al.
Letter to the Editor | Science Date: 10-Apr-2020 DOI: 10.1126/science.abb8905

Permanently ban wildlife consumption
Nian Yang et al.
Letter to the Editor | Science Date: 27-Mar-2020 DOI: 10.1126/science.abb1938

Wildlife consumption ban is insufficient
Hongxin Wang et al.
Letter to the Editor | Science Date: 27-Mar-2020 DOI: 10.1126/science.abb6463

COVID-19 drives new threat to bats in China
Huabin Zhao
Letter to the Editor | Science Date: 27-Mar-2020 DOI: 10.1126/science.abb3088

Travel restrictions violate international law
Benjamin Mason Meier et al.
Letter to the Editor | Science Date: 27-Mar-2020 DOI: 10.1126/science.abb6950

Aggregated mobility data could help fight COVID-19
Caroline O. Buckee et al.
Letter to the Editor | Science Date: 23-Mar-2020 DOI: 10.1126/science.abb8021

Preventing COVID-19 prejudice in academia
Piotr Rzymski, Michał Nowicki
Letter to the Editor | Science Date: 20-Mar-2020 DOI: 10.1126/science.abb4870

Misguided drug advice for COVID-19
Garret A. FitzGerald
Letter to the Editor | Science Date: 20-Mar-2020 DOI: 10.1126/science.abb8034

Blog Posts

Drawing the blueprint to a COVID-19 response
H. Holden Thorp
Editor's Blog Date: 27-Apr-2020

Expanding voices during the COVID-19 crisis
H. Holden Thorp
Editor's Blog Date: 7-Apr-2020

Adapting to the crisis
H. Holden Thorp
Editor's Blog Date: 3-Apr-2020

Additional Content

Sponsored Science webinar: Coronavirus: A survival guide

Science Podcasts: Interviews with reporters and researchers on the latest coronavirus stories

Video: How diseases rise and fall with the seasons—and what it could mean for coronavirus

Science Facebook Live: How understanding SARS-CoV-2 structure is informing vaccine design and clinical trials