Coronavirus: Research, Commentary, and News

The Science journals are striving to provide the best and most timely research, analysis, and news coverage of COVID-19 and the coronavirus that causes it. All content is free to access.

Read the latest: Science | Science Advances | Science Immunology | Science Robotics | Science Translational Medicine | News from Science | Letters to the Editor | Book Reviews | Blogs

Science

Introductions and early spread of SARS-CoV-2 in the New York City area
A. S. Gonzalez-Reiche et al.
Report | Science Date: 29-May-2020 DOI: 10.1126/science.abc1917

COVID-19 research in Africa
Linda-Gail Bekker, Valerie Mizrahi
Editorial | Science Date: 29-May-2020 DOI: 10.1126/science.abc9528

Moving academic research forward during COVID-19
N. S. Wigginton et al.
Policy Forum | Science Date: 28-May-2020 DOI: 10.1126/science.abc5599

Reducing transmission of SARS-CoV-2
Kimberly A. Prather, Chia C. Wang, Robert T. Schooley
Perspective | Science Date: 27-May-2020 DOI: 10.1126/science.abc6197

Suspend tests and rankings
H. Holden Thorp
Editorial | Science Date: 22-May-2020 DOI: 10.1126/science.abc8654

Which interventions work best in a pandemic?
J. Haushofer, C. J. E. Metcalf
Policy Forum | Science Date: 21-May-2020 DOI: 10.1126/science.abb6144

DNA vaccine protection against SARS-CoV-2 in rhesus macaques
Jingyou Yu et al.
Research Article | Science Date: 20-May-2020 DOI: 10.1126/science.abc6284

SARS-CoV-2 infection protects against rechallenge in rhesus macaques
Abishek Chandrashekar et al.
Research Article | Science Date: 20-May-2020 DOI: 10.1126/science.abc4776

Susceptible supply limits the role of climate in the early SARS-CoV-2 pandemic
Rachel E. Baker, Wenchang Yang, Gabriel A. Vecchi, C. Jessica E. Metcalf, Bryan T. Grenfell
Report | Science Date: 18-May-2020 DOI: 10.1126/science.abc2535

Serology assays to manage COVID-19
Florian Krammer, Viviana Simon
Perspective | Science Date: 15-May-2020 DOI: 10.1126/science.abc1227

Inferring change points in the spread of COVID-19 reveals the effectiveness of interventions
Jonas Dehning et al.
Research Article | Science Date: 15-May-2020 DOI: 10.1126/science.abb9789

Policy opportunity to enhance sharing for pandemic research
Michelle Rourke et al.
Policy Forum | Science Date: 15-May-2020 DOI: 10.1126/science.abb9342

Lessons from the crucible of crisis
Marcia McNutt
Editorial | Science Date: 15-May-2020 DOI: 10.1126/science.abc6866

Estimating the burden of SARS-CoV-2 in France
Henrik Salje et al.
Report | Science Date: 13-May-2020 DOI: 10.1126/science.abc3517

A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2
Yan Wu et al.
Report | Science Date: 13-May-2020 DOI: 10.1126/science.abc2241

Ethics and governance for digital disease surveillance
M. M. Mello and C. J. Wang
Policy Forum | Science Date: 11-May-2020 DOI: 10.1126/science.abb9045

A strategic approach to COVID-19 vaccine R&D
Lawrence Corey, John R. Mascola, Anthony S. Fauci, Francis S. Collins
Policy Forum | Science Date: 11-May-2020 DOI: 10.1126/science.abc5312

Both/and problem in an either/or world
H. Holden Thorp
Editorial | Science Date: 8-May-2020 DOI: 10.1126/science.abc6859

Rapid COVID-19 vaccine development
Barney S. Graham
Perspective | Science Date: 8-May-2020 DOI: 10.1126/science.abb8923

Rapid repurposing of drugs for COVID-19
R. K. Guy et al.
Perspective | Science Date: 8-May-2020 DOI: 10.1126/science.abb9332

Combination prevention for COVID-19
Myron S. Cohen and Lawrence Corey
Editorial | Science Date: 8-May-2020 DOI: 10.1126/science.abc5798

Beat COVID-19 through innovation
Pierre Azoulay and Benjamin Jones
Editorial | Science Date: 8-May-2020 DOI: 10.1126/science.abc5792

Ethics of controlled human infection to study COVID-19
S. K. Shah et al.
Policy Forum | Science Date: 7-May-2020 DOI: 10.1126/science.abc1076

Rapid development of an inactivated vaccine candidate for SARS-CoV-2
Qiang Gao et al.
Report | Science Date: 6-May-2020 DOI: 10.1126/science.abc1932

Rapid implementation of mobile technology for real-time epidemiology of COVID-19
David A. Drew et al.
Report | Science Date: 5-May-2020 DOI: 10.1126/science.abc0473

Site-specific glycan analysis of the SARS-CoV-2 spike
Yasunori Watanabe et al.
Report | Science Date: 4-May-2020 DOI: 10.1126/science.abb9983

Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir
Wanchao Yin et al.
Report | Science Date: 1-May-2020 DOI: 10.1126/science.abc1560

SARS-CoV-2 productively infects human gut enterocytes
Mart M. Lamers et al.
Research Article | Science Date: 1-May-2020 DOI: 10.1126/science.abc1669

COVID-19 amidst Ebola's retreat
John Ditekemena
Editorial | Science Date: 1-May-2020 DOI: 10.1126/science.abc4859

A COVID-19 recovery for climate
Daniel Rosenbloom and Jochen Markard
Editorial | Science Date: 1-May-2020 DOI: 10.1126/science.abc4887

Changes in contact patterns shape the dynamics of the COVID-19 outbreak in China
Juanjuan Zhang et al.
Report | Science Date: 29-Apr-2020 DOI: 10.1126/science.abb8001

Modeling infectious disease dynamics
Sarah Cobey
Perspective | Science Date: 24-Apr-2020 DOI: 10.1126/science.abb5659

Lost in transition
Kathleen Newland
Editorial | Science Date: 24-Apr-2020 DOI: 10.1126/science.abc3197

Against pandemic research exceptionalism
Alex John London, Jonathan Kimmelman
Policy Forum | Science Date: 23-Apr-2020 DOI: 10.1126/science.abc1731

Structure-b​ased design of antiviral drug candidates targeting the SARS-CoV-2 main protease
W. Dai et al.
Research Article | Science Date: 22-Apr-2020 DOI: 10.1126/science.abb4489

Why WHO?
H. Holden Thorp
Editorial | Science Date: 20-Apr-2020 DOI: 10.1126/science.abc3400

Comparative pathogenesis of COVID-19, MERS and SARS in a non-human primate model
Barry Rockx et al.
Report | Science Date: 17-Apr-2020 DOI: 10.1126/science.abb7314

Cytokine release syndrome in severe COVID-19
John B. Moore, Carl H. June
Perspective | Science Date: 17-Apr-2020 DOI: 10.1126/science.abb8925

The moment to see the poor
Joachim von Braun, Stefano Zamagni, Marcelo Sánchez Sorondo
Editorial | Science Date: 17-Apr-2020 DOI: 10.1126/science.abc2255

Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period
Stephen M. Kissler, Christine Tedijanto, Edward Goldstein, Yonatan H. Grad, Marc Lipsitch
Report | Science Date: 14-Apr-2020 DOI: 10.1126/science.abb5793

Structure of the RNA-dependent RNA polymerase from COVID-19 virus
Yan Gao et al.
Report | Science Date: 10-Apr-2020 DOI: 10.1126/science.abb7498

G20 leaders must answer to COVID-19
Caroline Atkinson
Editorial | Science Date: 10-Apr-2020 DOI: 10.1126/science.abc1025

Effective containment explains sub-exponential growth in recent confirmed COVID-19 cases in China 
Benjamin F. Maier, Dirk Brockmann
Research Article | Science Date: 8-Apr-2020 DOI: 10.1126/science.abb4557

Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS-coronavirus-2 
Jianzhong Shi et al.
Report | Science Date: 8-Apr-2020 DOI: 10.1126/science.abb7015

A highly conserved cryptic epitope in the receptor-binding domains of SARS-CoV-2 and SARS-CoV
Meng Yuan, Nicholas C. Wu, Xueyong Zhu, Chang-Chun D. Lee, Ray T. Y. So, Huibin Lv, Chris K. P. Mok, Ian A. Wilson
Report | Science Date: 3-Apr-2020 DOI: 10.1126/science.abb7269

Quantifying SARS-CoV-2 transmission suggests epidemic control with digital contact tracing
Luca Ferretti, Chris Wymant, Michelle Kendall, Lele Zhao, Anel Nurtay, Lucie Abeler-Dörner, Michael Parker, David Bonsall, Christophe Fraser
Research Article | Science Date: 31-Mar-2020 DOI: 10.1126/science.abb6936

An investigation of transmission control measures during the first 50 days of the COVID-19 epidemic in China
Huaiyu Tian, Yonghong Liu, Yidan Li, Chieh-Hsi Wu, Bin Chen, Moritz U. G. Kraemer, Bingying Li, Jun Cai, Bo Xu, Qiqi Yang, Ben Wang, Peng Yang, Yujun Cui, Yimeng Song, Pai Zheng, Quanyi Wang, Ottar N. Bjornstad, Ruifu Yang, Bryan T. Grenfell, Oliver G. Pybus, Christopher Dye
Report | Science Date: 31-Mar-2020 DOI: 10.1126/science.abb6105

This is real
H. Holden Thorp
Editorial | Science Date: 27-Mar-2020 DOI: 10.1126/science.abb9223

COVID-19 needs a big science approach
Seth Berkley
Editorial | Science Date: 25-Mar-2020 DOI: 10.1126/science.abb8654

The effect of human mobility and control measures on the COVID-19 epidemic in China
Moritz U. G. Kraemer, Chia-Hung Yang, Bernardo Gutierrez, Chieh-Hsi Wu, Brennan Klein, David M. Pigott, Open COVID-19 Data Working Group, Louis du Plessis, Nuno R. Faria, Ruoran Li, William P. Hanage, John S. Brownstein, Maylis Layan, Alessandro Vespignani, Huaiyu Tian, Christopher Dye, Oliver G. Pybus, Samuel V. Scarpino
Research Article | Science Date: 25-Mar-2020 DOI: 10.1126/science.abb4218

Underpromise, overdeliver
H. Holden Thorp
Editorial | Science Date: 23-Mar-2020 DOI: 10.1126/science.abb8492

Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors
Linlin Zhang, Daizong Lin, Xinyuanyuan Sun, Ute Curth, Christian Drosten, Lucie Sauerhering, Stephan Becker, Katharina Rox, Rolf Hilgenfeld
Report | Science Date: 20-Mar-2020 DOI: 10.1126/science.abb3405

Time to pull together
H. Holden Thorp
Editorial | Science Date: 16-Mar-2020 DOI: 10.1126/science.abb7518

Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV2)
Ruiyun Li, Sen Pei, Bin Chen, Yimeng Song, Tao Zhang, Wan Yang, Jeffrey Shaman
Research Article | Science Date: 16-Mar-2020 DOI: 10.1126/science.abb3221 

Do us a favor
H. Holden Thorp
Editorial | Science Date: 11-Mar-2020 DOI: 10.1126/science.abb6502

The effect of travel restrictions on the spread of the 2019 novel coronavirus (COVID-19) outbreak
Matteo Chinazzi, Jessica T. Davis, Marco Ajelli, Corrado Gioannini, Maria Litvinova, Stefano Merler, Ana Pastore y Piontti, Kunpeng Mu, Luca Rossi, Kaiyuan Sun, Cécile Viboud, Xinyue Xiong, Hongjie Yu, M. Elizabeth Halloran, Ira M. Longini Jr., Alessandro Vespignani
Research Article | Science Date: 6-Mar-2020 DOI: 10.1126/science.aba9757

Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2
Renhong Yan, Yuanyuan Zhang, Yaning Li, Lu Xia, Yingying Guo, Qiang Zhou
Research Article | Science Date: 4-Mar-2020 DOI: 10.1126/science.abb2762

The costs of secrecy
H. Holden Thorp
Editorial | Science Date: 28-Feb-2020 DOI: 10.1126/science.abb4420

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
Daniel Wrapp, Nianshuang Wang, Kizzmekia S. Corbett, Jory A. Goldsmith, Ching-Lin Hsieh, Olubukola Abiona, Barney S. Graham, Jason S. McLellan
Report | Science Date: 19-Feb-2020 DOI: 10.1126/science.abb2507

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Science Advances

COVID-19 and the next influenza season
Benjamin D. Singer
Editorial | Science Advances Date: 29-May-2020 DOI: 10.1126/sciadv.abd0086

Emergence of SARS-CoV-2 through Recombination and Strong Purifying Selection
Li et al.
Research Article | Science Advances Date: 29-May-2020 DOI: 10.1126/sciadv.abb9153

SARS-CoV-2 vaccines: Slow is fast
Douglas R. Green
Editorial | Science Advances Date: 22-May-2020 DOI: 10.1126/sciadv.abc7428

Evidence for host-dependent RNA editing in the transcriptome of SARS-CoV-2 in humans
Di Giorgio et al.
Research Article | Science Advances Date: 18-May-2020 DOI: 10.1126/sciadv.abb5813

COVID-19: Rescue by transcriptional inhibition
Ali Shilatifard
Editorial | Science Advances Date: 11-May-2020 DOI: 10.1126/sciadv.abc6891

Point of no return: COVID-19 and the US healthcare system
An emergency physician's perspective

Maia Dorsett
Editorial | Science Advances Date: 7-May-2020 DOI: 10.1126/sciadv.abc5354

A single dose of ChAdOx1 MERS provides protective immunity in rhesus macaques
Neeltje van Doremalen et al.
Research Article | Science Advances Date: 1-May-2020 DOI: 10.1126/sciadv.aba8399

Mobile phone data for informing public health actions across the COVID-19 pandemic lifecycle
Nuria Oliver, Bruno Lepri, Harald Sterly, Renaud Lambiotte, Sébastien Delataille, Marco De Nadai, Emmanuel Letouzé, Albert Ali Salah, Richard Benjamins, Ciro Cattuto, Vittoria Colizza, Nicolas de Cordes, Samuel P. Fraiberger, Til Koebe, Sune Lehmann, Juan Murillo, Alex Pentland, Phuong N. Pham, Frédéric Pivetta, Jari Saramaki, Samuel V. Scarpino, Michele Tizzoni, Stefaan Vehulst, Patrick Vinck
Editorial | Science Advances Date: 27-Apr-2020 DOI: 10.1126/sciadv.abc0764

Squalene-based multidrug nanoparticles for improved mitigation of uncontrolled inflammation
Flavio Dormont et al.
Research Article | Science Advances Date: 27-Apr-2020 DOI: 10.1126/sciadv.aaz5466

Medicine in the time of corona: Fundamental molecular research is “essential”
Ali Shilatifard
Editorial | Science Advances Date: 21-Apr-2020 DOI: 10.1126/sciadv.abc2800

Surviving COVID-19: A disease tolerance perspective
Janelle S. Ayres
Editorial | Science Advances Date: 17-Apr-2020 DOI: 10.1126/sciadv.abc1518

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Science Immunology

Serology for SARS-CoV-2: Apprehensions, opportunities, and the path forward
Juliet E. Bryant et al.
Focus | Science Immunology Date: 19-May-2020 DOI: 10.1126/sciimmunol.abc6347

TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes
Ruochen Zang et al.
Research Article | Science Immunology Date: 13-May-2020 DOI: 10.1126/sciimmunol.abc3582

HiJAKing SARS-CoV-2? The potential role of JAK inhibitors in the management of COVID-19
Francesca Romana Spinelli et al.
Focus | Science Immunology Date: 8-May-2020 DOI: 10.1126/sciimmunol.abc5367

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Science Robotics

Combating COVID-19—The role of robotics in managing public health and infectious diseases
Guang-Zhong Yang, Bradley J. Nelson, Robin R. Murphy, Howie Choset, Henrik Christensen, Steven H. Collins, Paolo Dario, Ken Goldberg, Koji Ikuta, Neil Jacobstein, Danica Kragic, Russell H. Taylor, Marcia McNutt
Editorial | Science Robotics Date: 25-Mar-2020 DOI: 10.1126/scirobotics.abb5589

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Science Translational Medicine

A rapidly deployable individualized system for augmenting ventilator capacity
Shriya Srinivasan et al.
Report | Science Translational Medicine Issue Date: 18-May-2020 DOI: 10.1126/scitranslmed.abb9401

An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice
Timothy P. Sheahan, Amy C. Sims, Shuntai Zho, Rachel L. Graham, Andrea J. Pruijssers, Maria L. Agostini, Sarah R. Leist, Alexandra Schäfer, Kenneth H. Dinnon III, Laura J. Stevens, James D. Chappell, Xiaotao Lu, Tia M. Hughes, Amelia S. George, Collin S. Hill, Stephanie A. Montgomery, Ariane J. Brown, Gregory R. Bluemling, Michael G. Natchus, Manohar Saindane, Alexander A. Kolykhalov, George Painter, Jennifer Harcourt, Azaibi Tamin, Natalie J. Thornburg, Ronald Swanstrom, Mark R. Denison, Ralph S. Baric
Research Article | Science Translational Medicine Date: 6-Apr-2020 DOI: 10.1126/scitranslmed.abb5883

New coronavirus outbreak: Framing questions for pandemic prevention
Scott P. Layne, James M. Hyman, David M. Morens, Jeffrey K. Taubenberger
Editorial | Science Translational Medicine Date: 11-Mar-2020 DOI: 10.1126/scitranslmed.abb1469

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News from Science

Science's COVID-19 reporting is supported by the Pulitzer Center.

Highlighted story: Blood vessel attack could trigger coronavirus’ fatal ‘second phase’

Operation Warp Speed selects billionaire scientist’s COVID-19 vaccine for monkey tests

How does coronavirus kill? Clinicians trace a ferocious rampage through the body, from brain to toes

Visit News from Science for more coronavirus coverage (or use our COVID-19 RSS news feed).

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Letters to the Editor

Ease restrictions on U.S. blood donations
Chirag Vasavda et al.
Letter to the Editor | Science Date: 29-May-2020 DOI: 10.1126/science.abc2322

The precarious position of postdocs during COVID-19
M. Arslan Ahmed et al.
Letter to the Editor | Science Date: 29-May-2020 DOI: 10.1126/science.abc5143

COVID-19 recovery can benefit biodiversity
Ryan M. Pearson et al.
Letter to the Editor | Science Date: 22-May-2020 DOI: 10.1126/science.abc1430

COVID-19 spotlights medical diagnostics
Maurycy Jankowski et al.
Letter to the Editor | Science Date: 22-May-2020 DOI: 10.1126/science.abb8952

Impact of COVID-19 on academic mothers
F. Staniscuaski et al.
Letter to the Editor | Science Date: 15-May-2020 DOI: 10.1126/science.abc2740

Support early-career field researchers
D. W. Inouye et al.
Letter to the Editor | Science Date: 15-May-2020 DOI: 10.1126/science.abc1261

Preserve Global South's research capacity
D. Reidpath et al.
Letter to the Editor | Science Date: 15-May-2020 DOI: 10.1126/science.abc2677

Call for transparency of COVID-19 models
C. Michael Barton et al.
Letter to the Editor | Science Date: 1-May-2020 DOI: 10.1126/science.abb8637

Research opportunities in pandemic lockdown
Rajeev Saraswat, Divya Atri Saraswat
Letter to the Editor | Science Date: 30-April-2020 DOI: 10.1126/science.abc3372

Protect Indigenous peoples from COVID-19
Lucas Ferrante, Philip M. Fearnside
Letter to the Editor | Science Date: 17-Apr-2020 DOI: 10.1126/science.abc0073

Protecting older adults during social distancing
Ali Jawaid
Letter to the Editor | Science Date: 10-Apr-2020 DOI: 10.1126/science.abb7885

Disinfection threatens aquatic ecosystems
Hong Zhang et al.
Letter to the Editor | Science Date: 10-Apr-2020 DOI: 10.1126/science.abb8905

Permanently ban wildlife consumption
Nian Yang et al.
Letter to the Editor | Science Date: 27-Mar-2020 DOI: 10.1126/science.abb1938

Wildlife consumption ban is insufficient
Hongxin Wang et al.
Letter to the Editor | Science Date: 27-Mar-2020 DOI: 10.1126/science.abb6463

COVID-19 drives new threat to bats in China
Huabin Zhao
Letter to the Editor | Science Date: 27-Mar-2020 DOI: 10.1126/science.abb3088

Travel restrictions violate international law
Benjamin Mason Meier et al.
Letter to the Editor | Science Date: 27-Mar-2020 DOI: 10.1126/science.abb6950

Aggregated mobility data could help fight COVID-19
Caroline O. Buckee et al.
Letter to the Editor | Science Date: 23-Mar-2020 DOI: 10.1126/science.abb8021

Preventing COVID-19 prejudice in academia
Piotr Rzymski, Michał Nowicki
Letter to the Editor | Science Date: 20-Mar-2020 DOI: 10.1126/science.abb4870

Misguided drug advice for COVID-19
Garret A. FitzGerald
Letter to the Editor | Science Date: 20-Mar-2020 DOI: 10.1126/science.abb8034

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Book Reviews

Tinctures of time and Schrödinger's virus
Luis Campos
Book Review | Science Date: 1-May-2020 DOI: 10.1126/science.abc1732

The other public health crisis
Joanna Schug
Book Review | Science Date: 1-May-2020 DOI: 10.1126/science.abb3582

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Blogs

Guest blogs
H. Holden Thorp
Blog post | Science Date: 12-May-2020

Reading the pandemic data
Jeffrey M. Zacks and Steven L. Franconeri
Blog post | Science Date: 12-May-2020

The end of the handshake?
Cato T. Laurencin and Aneesah McClinton
Blog post | Science Date: 12-May-2020

Drawing the blueprint to a COVID-19 response
H. Holden Thorp
Blog post | Science Date: 27-Apr-2020

Expanding voices during the COVID-19 crisis
H. Holden Thorp
Blog post | Science Date: 7-Apr-2020

Adapting to the crisis
H. Holden Thorp
Blog post | Science Date: 3-Apr-2020

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Additional Content

Sponsored Science webinar: Coronavirus: A survival guide

Science Podcasts: Interviews with reporters and researchers on the latest coronavirus stories

Video: How diseases rise and fall with the seasons—and what it could mean for coronavirus

Science Facebook Live: How understanding SARS-CoV-2 structure is informing vaccine design and clinical trial