Coronavirus: Research, Commentary, and News

The Science journals are striving to provide the best and most timely research, analysis, and news coverage of COVID-19 and the coronavirus that causes it. All content is free to access.

Read the latest: Science | Science Advances | Science Immunology | Science Robotics | Science Signaling | Science Translational Medicine | News from Science | Letters to the Editor | Book Reviews | Blogs

Science

COVID-19 can affect the heart
Eric J. Topol
Perspective | Science Date: 23-Sep-2020 DOI: 10.1126/science.abe2813

Free fatty acid binding pocket in the locked structure of SARS-CoV-2 spike protein
Christine Toelzer et al.
Report | Science Date: 21-Sep-2020 DOI: 10.1126/science.abd3255

Immune life history, vaccination, and the dynamics of SARS-CoV-2 over the next 5 years
Chadi M. Saad-Roy et al.
Research Article | Science Date: 21-Sep-2020 DOI: 10.1126/science.abd7343

COVID-19 in children and young people
Matthew D. Snape and Russell M. Viner
Perspective | Science Date: 21-Sep-2020 DOI: 10.1126/science.abd6165

Trump lied about science
H. Holden Thorp
Editorial | Science Date: 11-Sep-2020 DOI: 10.1126/science.abe7391

Coronavirus dons a new crown
Nuruddin Unchwaniwala and Paul Ahlquist
Perspective | Science Date: 11-Sep-2020 DOI: 10.1126/science.abe0322

The emergence of SARS-CoV-2 in Europe and North America
Michael Worobey et al.
Research Article | Science Date: 10-Sep-2020 DOI: 10.1126/science.abc8169

Cryptic transmission of SARS-CoV-2 in Washington state
Trevor Bedford et al.
Report | Science Date: 10-Sep-2020 DOI: 10.1126/science.abc0523

De novo design of picomolar SARS-CoV-2 miniprotein inhibitors
Longxing Cao et al.
Research Article | Science Date: 9-Sep-2020 DOI: 10.1126/science.abd9909

Reopening schools during COVID-19
Ronan Lordan, Garret A. FitzGerald, Tilo Grosser
Editorial | Science Date: 4-Sep-2020 DOI: 10.1126/science.abe5765

A molecular trap against COVID-19
Brandon J. DeKosky
Perspective | Science Date: 4-Sep-2020 DOI: 10.1126/science.abe0010

An ethical framework for global vaccine allocation
Ezekiel J. Emanuel
Policy Forum | Science Date: 3-Sep-2020 DOI: 10.1126/science.abe2803

Bridging digital health divides
Anurag Agrawal
Perspective | Science Date: 28-Aug-2020 DOI: 10.1126/science.abc9295

MHC class II transactivator CIITA induces cell resistance to Ebola virus and SARS-like coronaviruses
Anna Bruchez et al.
Report | Science Date: 27-Aug-2020 DOI: 10.1126/science.abb3753

In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges
Beata Turoňová et al.
Research Article | Science Date: 18-Aug-2020 DOI: 10.1126/science.abd5223

Vaccine nationalism’s politics
David P. Fidler
Editorial | Science Date: 14-Aug-2020 DOI: 10.1126/science.abe2275

A dangerous rush for vaccines
H. Holden Thorp
Editorial | Science Date: 13-Aug-2020 DOI: 10.1126/science.abe3147

Knowledge transfer for large-scale vaccine manufacturing
W. Nicholson Price II, Arti K. Rai, Timo Minssen
Policy Forum | Science Date: 13-Aug-2020 DOI: 10.1126/science.abc9588

Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans
Prabhu S. Arunachalam et al.
Research Article | Science Date: 11-Aug-2020 DOI: 10.1126/science.abc6261

COVID-19 in Africa: Dampening the storm?
Moustapha Mbow et al.
Perspective | Science Date: 7-Aug-2020 DOI: 10.1126/science.abd3902

Productivity in a pandemic
Caitlyn Collins
Editorial | Science Date: 7-Aug-2020 DOI: 10.1126/science.abe1163

Interferon responses in viral pneumonias
Gary E. Grajales-Reyes and Marco Colonna
Perspective | Science Date: 7-Aug-2020 DOI: 10.1126/science.abd2208

A molecular pore spans the double membrane of the coronavirus replication organelle
Georg Wolff et al.
Report | Science Date: 6-Aug-2020 DOI: 10.1126/science.abd3629

Engineering human ACE2 to optimize binding to the spike protein of SARS coronavirus 2
Kui K. Chan et al.
Report | Science Date: 4-Aug-2020 DOI: 10.1126/science.abc0870

Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans
Jose Mateus et al.
Research Article | Science Date: 4-Aug-2020 DOI: 10.1126/science.abd3871

Cautious optimism
H. Holden Thorp
Editorial | Science Date: 31-Jul-2020 DOI: 10.1126/science.abe0359

How does SARS-CoV-2 cause COVID-19?
Nicholas J. Matheson and Paul J. Lehner
Perspective | Science Date: 31-Jul-2020 DOI: 10.1126/science.abc6156

COVID-19 risks to global food security
David Laborde, Will Martin, Johan Swinnen, Rob Vos
Policy Forum | Science Date: 31-Jul-2020 DOI: 10.1126/science.abc4765

Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine efficacy
Hongjing Gu et al.
Research Article | Science Date: 30-Jul-2020 DOI: 10.1126/science.abc4730

COVID-19 affects HIV and tuberculosis care
Quarraisha Abdool Karim and Salim S. Abdool Karim
Perspective | Science Date: 24-Jul-2020 DOI: 10.1126/science.abd1072

Mathematical models to guide pandemic response
C. Jessica E. Metcalf, Dylan H. Morris, Sang Woo Park
Perspective | Science Date: 24-Jul-2020 DOI: 10.1126/science.abd1668

The COVID-19 pandemic and human fertility
A. Aassve, N. Cavalli, L. Mencarini, S. Plach, M. Livi Bacci
Perspective | Science Date: 24-Jul-2020 DOI: 10.1126/science.abc9520

Ecology and economics for pandemic prevention
Andrew P. Dobson et al.
Policy Forum | Science Date: 24-Jul-2020 DOI: 10.1126/science.abc3189

Structure-based design of prefusion-stabilized SARS-CoV-2 spikes
Ching-Lin Hsieh et al.
Report | Science Date: 23-Jul-2020 DOI: 10.1126/science.abd0826

Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody
Zhe Lv et al.
Report | Science Date: 23-Jul-2020 DOI: 10.1126/science.abc5881

Evolution and epidemic spread of SARS-CoV-2 in Brazil
Darlan S. Candido et al.
Report | Science Date: 23-Jul-2020 DOI: 10.1126/science.abd2161

Distinct conformational states of SARS-CoV-2 spike protein
Yongfei Cai et al.
Research Article | Science Date: 21-Jul-2020 DOI: 10.1126/science.abd4251

Serial interval of SARS-CoV-2 was shortened over time by nonpharmaceutical interventions
Sheikh Taslim Ali et al.
Report | Science Date: 21-Jul-2020 DOI: 10.1126/science.abc9004

Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2
Matthias Thoms et al.
Report | Science Date: 17-Jul-2020 DOI: 10.1126/science.abc8665

Assessing the impact of coordinated COVID-19 exit strategies across Europe
N. W. Ruktanonchai et al.
Research Article | Science Date: 17-Jul-2020 DOI: 10.1126/science.abc5096

Aging immunity may exacerbate COVID-19
Arne N. Akbar, Derek W. Gilroy
Perspective | Science Date: 17-Jul-2020 DOI: 10.1126/science.abb0762

Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications
Divij Mathew et al.
Research Article | Science Date: 15-Jul-2020 DOI: 10.1126/science.abc8511

Structural basis of a shared antibody response to SARS-CoV-2
Meng Yuan et al.
Report | Science Date: 13-Jul-2020 DOI: 10.1126/science.abd2321

Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients
Jérôme Hadjadj et al.
Report | Science Date: 13-Jul-2020 DOI: 10.1126/science.abc6027

Rigorous wildlife disease surveillance
M. Watsa and Wildlife Disease Surveillance Focus Group
Perspective | Science Date: 10-Jul-2020 DOI: 10.1126/science.abc0017

Surviving the trauma of COVID-19
Roxane Cohen Silver
Editorial | Science Date: 3-Jul-2020 DOI: 10.1126/science.abd5396

Primary exposure to SARS-CoV-2 protects against reinfection in rhesus macaques
Wei Deng et al.
Report | Science Date: 2-Jul-2020 DOI: 10.1126/science.abc5343

A mathematical model reveals the influence of population heterogeneity on herd immunity to SARS-CoV-2
Tom Britton et al.
Report | Science Date: 23-Jun-2020 DOI: 10.1126/science.abc6810

A neutralizing human antibody binds to the N-terminal domain of the Spike protein of SARS-CoV-2
Xiangyang Chi et al.
Research Article | Science Date: 22-Jun-2020 DOI: 10.1126/science.abc6952

COVID-19 and cancer
Norman E. Sharpless
Editorial | Science Date: 19-Jun-2020 DOI: 10.1126/science.abd3377

Unexpected air pollution with marked emission reductions during the COVID-19 outbreak in China
Tianhao Le et al.
Report | Science Date: 17-Jun-2020 DOI: 10.1126/science.abb7431

Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies
Alina Baum et al.
Report | Science Date: 15-Jun-2020 DOI: 10.1126/science.abd0831

Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability
Philip J. M. Brouwer et al.
Research Article | Science Date: 15-Jun-2020 DOI: 10.1126/science.abc5902

Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail
Johanna Hansen et al.
Report | Science Date: 15-Jun-2020 DOI: 10.1126/science.abd0827

Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model
Thomas F. Rogers et al.
Research Article | Science Date: 15-Jun-2020 DOI: 10.1126/science.abc7520

Broad neutralization of SARS-related viruses by human monoclonal antibodies
A. Z. Wec et al.
Report | Science Date: 15-Jun-2020 DOI: 10.1126/science.abc7424

The impact of COVID-19 and strategies for mitigation and suppression in low- and middle-income countries
Patrick G. T. Walker
Research Article | Science Date: 12-Jun-2020 DOI: 10.1126/science.abc0035

COVID-19 and flu, a perfect storm
Edward A. Belongia, Michael T. Osterholm
Editorial | Science Date: 12-Jun-2020 DOI: 10.1126/science.abd2220

Type I and III interferons disrupt lung epithelial repair during recovery from viral infection
Jack Major et al.
Report | Science Date: 11-Jun-2020 DOI: 10.1126/science.abc2061

Type III interferons disrupt the lung epithelial barrier upon viral recognition
Achille Broggi et al.
Report | Science Date: 11-Jun-2020 DOI: 10.1126/science.abc3545

Genomic surveillance reveals multiple introductions of SARS-CoV-2 into Northern California
Xianding Deng et al.
Report | Science Date: 8-Jun-2020 DOI: 10.1126/science.abb9263

Patents, economics, and pandemics
Will Zerhouni, Gary J. Nabel, Elias Zerhouni
Editorial | Science Date: 5-Jun-2020 DOI: 10.1126/science.abc7472

Introductions and early spread of SARS-CoV-2 in the New York City area
A. S. Gonzalez-Reiche et al.
Report | Science Date: 29-May-2020 DOI: 10.1126/science.abc1917

COVID-19 research in Africa
Linda-Gail Bekker, Valerie Mizrahi
Editorial | Science Date: 29-May-2020 DOI: 10.1126/science.abc9528

Moving academic research forward during COVID-19
N. S. Wigginton et al.
Policy Forum | Science Date: 28-May-2020 DOI: 10.1126/science.abc5599

Reducing transmission of SARS-CoV-2
Kimberly A. Prather, Chia C. Wang, Robert T. Schooley
Perspective | Science Date: 27-May-2020 DOI: 10.1126/science.abc6197

Suspend tests and rankings
H. Holden Thorp
Editorial | Science Date: 22-May-2020 DOI: 10.1126/science.abc8654

Which interventions work best in a pandemic?
J. Haushofer, C. J. E. Metcalf
Policy Forum | Science Date: 21-May-2020 DOI: 10.1126/science.abb6144

DNA vaccine protection against SARS-CoV-2 in rhesus macaques
Jingyou Yu et al.
Research Article | Science Date: 20-May-2020 DOI: 10.1126/science.abc6284

SARS-CoV-2 infection protects against rechallenge in rhesus macaques
Abishek Chandrashekar et al.
Research Article | Science Date: 20-May-2020 DOI: 10.1126/science.abc4776

Susceptible supply limits the role of climate in the early SARS-CoV-2 pandemic
Rachel E. Baker, Wenchang Yang, Gabriel A. Vecchi, C. Jessica E. Metcalf, Bryan T. Grenfell
Report | Science Date: 18-May-2020 DOI: 10.1126/science.abc2535

Serology assays to manage COVID-19
Florian Krammer, Viviana Simon
Perspective | Science Date: 15-May-2020 DOI: 10.1126/science.abc1227

Inferring change points in the spread of COVID-19 reveals the effectiveness of interventions
Jonas Dehning et al.
Research Article | Science Date: 15-May-2020 DOI: 10.1126/science.abb9789

Policy opportunity to enhance sharing for pandemic research
Michelle Rourke et al.
Policy Forum | Science Date: 15-May-2020 DOI: 10.1126/science.abb9342

Lessons from the crucible of crisis
Marcia McNutt
Editorial | Science Date: 15-May-2020 DOI: 10.1126/science.abc6866

Estimating the burden of SARS-CoV-2 in France
Henrik Salje et al.
Report | Science Date: 13-May-2020 DOI: 10.1126/science.abc3517

A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2
Yan Wu et al.
Report | Science Date: 13-May-2020 DOI: 10.1126/science.abc2241

Ethics and governance for digital disease surveillance
M. M. Mello and C. J. Wang
Policy Forum | Science Date: 11-May-2020 DOI: 10.1126/science.abb9045

A strategic approach to COVID-19 vaccine R&D
Lawrence Corey, John R. Mascola, Anthony S. Fauci, Francis S. Collins
Policy Forum | Science Date: 11-May-2020 DOI: 10.1126/science.abc5312

Both/and problem in an either/or world
H. Holden Thorp
Editorial | Science Date: 8-May-2020 DOI: 10.1126/science.abc6859

Rapid COVID-19 vaccine development
Barney S. Graham
Perspective | Science Date: 8-May-2020 DOI: 10.1126/science.abb8923

Rapid repurposing of drugs for COVID-19
R. K. Guy et al.
Perspective | Science Date: 8-May-2020 DOI: 10.1126/science.abb9332

Combination prevention for COVID-19
Myron S. Cohen and Lawrence Corey
Editorial | Science Date: 8-May-2020 DOI: 10.1126/science.abc5798

Beat COVID-19 through innovation
Pierre Azoulay and Benjamin Jones
Editorial | Science Date: 8-May-2020 DOI: 10.1126/science.abc5792

Ethics of controlled human infection to study COVID-19
S. K. Shah et al.
Policy Forum | Science Date: 7-May-2020 DOI: 10.1126/science.abc1076

Rapid development of an inactivated vaccine candidate for SARS-CoV-2
Qiang Gao et al.
Report | Science Date: 6-May-2020 DOI: 10.1126/science.abc1932

Rapid implementation of mobile technology for real-time epidemiology of COVID-19
David A. Drew et al.
Report | Science Date: 5-May-2020 DOI: 10.1126/science.abc0473

Site-specific glycan analysis of the SARS-CoV-2 spike
Yasunori Watanabe et al.
Report | Science Date: 4-May-2020 DOI: 10.1126/science.abb9983

Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir
Wanchao Yin et al.
Report | Science Date: 1-May-2020 DOI: 10.1126/science.abc1560

SARS-CoV-2 productively infects human gut enterocytes
Mart M. Lamers et al.
Research Article | Science Date: 1-May-2020 DOI: 10.1126/science.abc1669

COVID-19 amidst Ebola's retreat
John Ditekemena
Editorial | Science Date: 1-May-2020 DOI: 10.1126/science.abc4859

A COVID-19 recovery for climate
Daniel Rosenbloom and Jochen Markard
Editorial | Science Date: 1-May-2020 DOI: 10.1126/science.abc4887

Changes in contact patterns shape the dynamics of the COVID-19 outbreak in China
Juanjuan Zhang et al.
Report | Science Date: 29-Apr-2020 DOI: 10.1126/science.abb8001

Modeling infectious disease dynamics
Sarah Cobey
Perspective | Science Date: 24-Apr-2020 DOI: 10.1126/science.abb5659

Lost in transition
Kathleen Newland
Editorial | Science Date: 24-Apr-2020 DOI: 10.1126/science.abc3197

Against pandemic research exceptionalism
Alex John London, Jonathan Kimmelman
Policy Forum | Science Date: 23-Apr-2020 DOI: 10.1126/science.abc1731

Structure-b​ased design of antiviral drug candidates targeting the SARS-CoV-2 main protease
W. Dai et al.
Research Article | Science Date: 22-Apr-2020 DOI: 10.1126/science.abb4489

Why WHO?
H. Holden Thorp
Editorial | Science Date: 20-Apr-2020 DOI: 10.1126/science.abc3400

Comparative pathogenesis of COVID-19, MERS and SARS in a non-human primate model
Barry Rockx et al.
Report | Science Date: 17-Apr-2020 DOI: 10.1126/science.abb7314

Cytokine release syndrome in severe COVID-19
John B. Moore, Carl H. June
Perspective | Science Date: 17-Apr-2020 DOI: 10.1126/science.abb8925

The moment to see the poor
Joachim von Braun, Stefano Zamagni, Marcelo Sánchez Sorondo
Editorial | Science Date: 17-Apr-2020 DOI: 10.1126/science.abc2255

Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period
Stephen M. Kissler, Christine Tedijanto, Edward Goldstein, Yonatan H. Grad, Marc Lipsitch
Report | Science Date: 14-Apr-2020 DOI: 10.1126/science.abb5793

Structure of the RNA-dependent RNA polymerase from COVID-19 virus
Yan Gao et al.
Report | Science Date: 10-Apr-2020 DOI: 10.1126/science.abb7498

G20 leaders must answer to COVID-19
Caroline Atkinson
Editorial | Science Date: 10-Apr-2020 DOI: 10.1126/science.abc1025

Effective containment explains sub-exponential growth in recent confirmed COVID-19 cases in China 
Benjamin F. Maier, Dirk Brockmann
Research Article | Science Date: 8-Apr-2020 DOI: 10.1126/science.abb4557

Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS-coronavirus-2 
Jianzhong Shi et al.
Report | Science Date: 8-Apr-2020 DOI: 10.1126/science.abb7015

A highly conserved cryptic epitope in the receptor-binding domains of SARS-CoV-2 and SARS-CoV
Meng Yuan, Nicholas C. Wu, Xueyong Zhu, Chang-Chun D. Lee, Ray T. Y. So, Huibin Lv, Chris K. P. Mok, Ian A. Wilson
Report | Science Date: 3-Apr-2020 DOI: 10.1126/science.abb7269

Quantifying SARS-CoV-2 transmission suggests epidemic control with digital contact tracing
Luca Ferretti, Chris Wymant, Michelle Kendall, Lele Zhao, Anel Nurtay, Lucie Abeler-Dörner, Michael Parker, David Bonsall, Christophe Fraser
Research Article | Science Date: 31-Mar-2020 DOI: 10.1126/science.abb6936

An investigation of transmission control measures during the first 50 days of the COVID-19 epidemic in China
Huaiyu Tian, Yonghong Liu, Yidan Li, Chieh-Hsi Wu, Bin Chen, Moritz U. G. Kraemer, Bingying Li, Jun Cai, Bo Xu, Qiqi Yang, Ben Wang, Peng Yang, Yujun Cui, Yimeng Song, Pai Zheng, Quanyi Wang, Ottar N. Bjornstad, Ruifu Yang, Bryan T. Grenfell, Oliver G. Pybus, Christopher Dye
Report | Science Date: 31-Mar-2020 DOI: 10.1126/science.abb6105

This is real
H. Holden Thorp
Editorial | Science Date: 27-Mar-2020 DOI: 10.1126/science.abb9223

COVID-19 needs a big science approach
Seth Berkley
Editorial | Science Date: 25-Mar-2020 DOI: 10.1126/science.abb8654

The effect of human mobility and control measures on the COVID-19 epidemic in China
Moritz U. G. Kraemer, Chia-Hung Yang, Bernardo Gutierrez, Chieh-Hsi Wu, Brennan Klein, David M. Pigott, Open COVID-19 Data Working Group, Louis du Plessis, Nuno R. Faria, Ruoran Li, William P. Hanage, John S. Brownstein, Maylis Layan, Alessandro Vespignani, Huaiyu Tian, Christopher Dye, Oliver G. Pybus, Samuel V. Scarpino
Research Article | Science Date: 25-Mar-2020 DOI: 10.1126/science.abb4218

Underpromise, overdeliver
H. Holden Thorp
Editorial | Science Date: 23-Mar-2020 DOI: 10.1126/science.abb8492

Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors
Linlin Zhang, Daizong Lin, Xinyuanyuan Sun, Ute Curth, Christian Drosten, Lucie Sauerhering, Stephan Becker, Katharina Rox, Rolf Hilgenfeld
Report | Science Date: 20-Mar-2020 DOI: 10.1126/science.abb3405

Time to pull together
H. Holden Thorp
Editorial | Science Date: 16-Mar-2020 DOI: 10.1126/science.abb7518

Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV2)
Ruiyun Li, Sen Pei, Bin Chen, Yimeng Song, Tao Zhang, Wan Yang, Jeffrey Shaman
Research Article | Science Date: 16-Mar-2020 DOI: 10.1126/science.abb3221 

Do us a favor
H. Holden Thorp
Editorial | Science Date: 11-Mar-2020 DOI: 10.1126/science.abb6502

The effect of travel restrictions on the spread of the 2019 novel coronavirus (COVID-19) outbreak
Matteo Chinazzi, Jessica T. Davis, Marco Ajelli, Corrado Gioannini, Maria Litvinova, Stefano Merler, Ana Pastore y Piontti, Kunpeng Mu, Luca Rossi, Kaiyuan Sun, Cécile Viboud, Xinyue Xiong, Hongjie Yu, M. Elizabeth Halloran, Ira M. Longini Jr., Alessandro Vespignani
Research Article | Science Date: 6-Mar-2020 DOI: 10.1126/science.aba9757

Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2
Renhong Yan, Yuanyuan Zhang, Yaning Li, Lu Xia, Yingying Guo, Qiang Zhou
Research Article | Science Date: 4-Mar-2020 DOI: 10.1126/science.abb2762

The costs of secrecy
H. Holden Thorp
Editorial | Science Date: 28-Feb-2020 DOI: 10.1126/science.abb4420

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
Daniel Wrapp, Nianshuang Wang, Kizzmekia S. Corbett, Jory A. Goldsmith, Ching-Lin Hsieh, Olubukola Abiona, Barney S. Graham, Jason S. McLellan
Report | Science Date: 19-Feb-2020 DOI: 10.1126/science.abb2507

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Science Advances

The unfolding COVID-19 pandemic: A probability-based, nationally representative study of mental health in the U.S.
E. A. Holman et al.
Research Article | Science Advances Date: 18-Sep-2020 DOI: 10.1126/sciadv.abd5390

Antibody-like proteins that capture and neutralize SARS-CoV-2
T. Kondo et al.
Research Article | Science Advances Date: 18-Sep-2020 DOI: 10.1126/sciadv.abd3916

Efficient high-throughput SARS-CoV-2 testing to detect asymptomatic carriers
N. Shental et al.
Research Article | Science Advances Date: 21-Aug-2020 DOI: 10.1126/sciadv.abc5961

Programmable low-cost DNA-based platform for viral RNA detection
L. Zhou et al.
Research Article | Science Advances Date: 21-Aug-2020 DOI: 10.1126/sciadv.abc6246

Molecular characterization of Ebselen binding activity to SARS-CoV-2 main protease
C. A. Menendez et al.
Research Article | Science Advances Date: 14-Aug-2020 DOI: 10.1126/sciadv.abd0345

Viruses harness YxxØ motif to interact with host AP2M1 for replication: a vulnerable broad-spectrum antiviral target
S. Yuan et al.
Research Article | Science Advances Date: 14-Aug-2020 DOI: 10.1126/sciadv.aba7910

Estimation of incubation period distribution of COVID-19 using disease onset forward time: a novel cross-sectional and forward follow-up study
J. Qin et al.
Research Article | Science Advances Date: 7-Aug-2020 DOI: 10.1126/sciadv.abc1202

Low-cost measurement of facemask efficacy for filtering expelled droplets during speech
Fischer et al.
Research Article | Science Advances Date: 7-Aug-2020 DOI: 10.1126/sciadv.abd3083

Mandated Bacillus Calmette-Guérin (BCG) vaccination predicts flattened curves for the spread of COVID-19
M. K. Berg et al.
Research Article | Science Advances Date: 31-Jul-2020 DOI: 10.1126/sciadv.abc1463

A single molecular descriptor to predict solution behavior of therapeutic antibodies
J. S. Kingsbury et al.
Research Article | Science Advances Date: 31-Jul-2020 DOI: 10.1126/sciadv.abb0372

Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia
D. H. Brann et al.
Research Article | Science Advances  Date: 24-Jul-2020 DOI: 10.1126/sciadv.abc5801

Acetylated K676 TGFBIp as a severity diagnostic blood biomarker for SARS-CoV-2 pneumonia
H. H. Park et al.
Research Article | Science Advances  Date: 24-Jul-2020 DOI: 10.1126/sciadv.abc1564

Cancer did not stay home for COVID-19
R. L Levine
Editorial | Science Advances Date: 17-Jul-2020 DOI: 10.1126/sciadv.abd7487

Continuous on-body sensing for the COVID-19 pandemic: Gaps and opportunities
H. Jeong et al. 
Editorial | Science Advances Date: 1-Jul-2020 DOI: 10.1126/sciadv.abd4794 

Structure-based drug designing and immunoinformatics approach for SARS-CoV-2
Panda et al. 
Research Article | Science Advances Date: 24-Jun-2020 DOI: 10.1126/sciadv.abb8097

Elusive consensus: Polarization in elite communication on the COVID-19 pandemic
J.Green et al.
Research Article | Science Advances Date: 24-Jun-2020 DOI: 10.1126/sciadv.abc2717

Abrupt decline in tropospheric nitrogen dioxide over China after the outbreak of COVID-19
Fei Liu et al.
Research Article | Science Advances Date: 12-Jun-2020 DOI: 10.1126/sciadv.abc2992 

Pandemics and the global environment
Hodges and Jackson
Editorial | Science Advances Date: 12-Jun-2020 DOI: 10.1126/sciadv.abd1325 

Medical education in the time of COVID-19
D.B.Wayne et al.
Editorial | Science Advances Date: 5-Jun-2020 DOI: 10.1126/sciadv.abc7110 

COVID-19 and the next influenza season
Benjamin D. Singer
Editorial | Science Advances Date: 29-May-2020 DOI: 10.1126/sciadv.abd0086

Emergence of SARS-CoV-2 through Recombination and Strong Purifying Selection
Li et al.
Research Article | Science Advances Date: 29-May-2020 DOI: 10.1126/sciadv.abb9153

SARS-CoV-2 vaccines: Slow is fast
Douglas R. Green
Editorial | Science Advances Date: 22-May-2020 DOI: 10.1126/sciadv.abc7428

Evidence for host-dependent RNA editing in the transcriptome of SARS-CoV-2 in humans
Di Giorgio et al.
Research Article | Science Advances Date: 18-May-2020 DOI: 10.1126/sciadv.abb5813

COVID-19: Rescue by transcriptional inhibition
Ali Shilatifard
Editorial | Science Advances Date: 11-May-2020 DOI: 10.1126/sciadv.abc6891

Point of no return: COVID-19 and the US healthcare system
An emergency physician's perspective

Maia Dorsett
Editorial | Science Advances Date: 7-May-2020 DOI: 10.1126/sciadv.abc5354

A single dose of ChAdOx1 MERS provides protective immunity in rhesus macaques
Neeltje van Doremalen et al.
Research Article | Science Advances Date: 1-May-2020 DOI: 10.1126/sciadv.aba8399

Mobile phone data for informing public health actions across the COVID-19 pandemic lifecycle
Nuria Oliver, Bruno Lepri, Harald Sterly, Renaud Lambiotte, Sébastien Delataille, Marco De Nadai, Emmanuel Letouzé, Albert Ali Salah, Richard Benjamins, Ciro Cattuto, Vittoria Colizza, Nicolas de Cordes, Samuel P. Fraiberger, Til Koebe, Sune Lehmann, Juan Murillo, Alex Pentland, Phuong N. Pham, Frédéric Pivetta, Jari Saramaki, Samuel V. Scarpino, Michele Tizzoni, Stefaan Vehulst, Patrick Vinck
Editorial | Science Advances Date: 27-Apr-2020 DOI: 10.1126/sciadv.abc0764

Squalene-based multidrug nanoparticles for improved mitigation of uncontrolled inflammation
Flavio Dormont et al.
Research Article | Science Advances Date: 27-Apr-2020 DOI: 10.1126/sciadv.aaz5466

Medicine in the time of corona: Fundamental molecular research is “essential”
Ali Shilatifard
Editorial | Science Advances Date: 21-Apr-2020 DOI: 10.1126/sciadv.abc2800

Surviving COVID-19: A disease tolerance perspective
Janelle S. Ayres
Editorial | Science Advances Date: 17-Apr-2020 DOI: 10.1126/sciadv.abc1518

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Science Immunology

Longitudinal immune profiling reveals key myeloid signatures associated with COVID-19
Elizabeth R. Mann et al.
Research Article | Science Immunology Date: 17-Sep-2020 DOI: 10.1126/sciimmunol.abd6197

Natural killer cell immunotypes related to COVID-19 disease severity
Christopher Maucourant et al.
Research Article | Science Immunology Date: 21-Aug-2020 DOI: 10.1126/sciimmunol.abd6832

SARS-CoV-2 seroprevalence among parturient women in Philadelphia
Dustin D. Flannery et al.
Report | Science Immunology Date: 29-Jul-2020 DOI: 10.1126/sciimmunol.abd5709

SARS-CoV-2 T cell immunity: Specificity, function, durability, and role in protection
Daniel M. Altmann and Rosemary J. Boyton
Perspective | Science Immunology Date: 17-Jul-2020 DOI: 10.1126/sciimmunol.abd6160

Comprehensive mapping of immune perturbations associated with severe COVID-19
Leticia Kuri-Cervantes et al.
Research Article | Science Immunology Date: 15-Jul-2020 DOI: 10.1126/sciimmunol.abd7114

Immunophenotyping of COVID-19 and influenza highlights the role of type I interferons in development of severe COVID-19
Jeong Seok Lee et al.
Research Article | Science Immunology Date: 10-Jul-2020 DOI: 10.1126/sciimmunol.abd1554

Phenotype and kinetics of SARS-CoV-2-specific T cells in COVID-19 patients with acute respiratory distress syndrome
Daniela Weiskopf et al.
Research Article | Science Immunology Date: 26-Jun-2020 DOI: 10.1126/sciimmunol.abd2071

The receptor binding domain of the viral spike protein is an immunodominant and highly specific target of antibodies in SARS-CoV-2 patients
Lakshmanane Premkumar et al.
Research Article | Science Immunology Date: 11-Jun-2020 DOI: 10.1126/sciimmunol.abc8413

Inhibition of Bruton tyrosine kinase in patients with severe COVID-19
Mark Roschewski et al.
Research Article | Science Immunology Date: 5-Jun-2020 DOI: 10.1126/sciimmunol.abd0110

Serology for SARS-CoV-2: Apprehensions, opportunities, and the path forward
Juliet E. Bryant et al.
Focus | Science Immunology Date: 19-May-2020 DOI: 10.1126/sciimmunol.abc6347

TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes
Ruochen Zang et al.
Research Article | Science Immunology Date: 13-May-2020 DOI: 10.1126/sciimmunol.abc3582

HiJAKing SARS-CoV-2? The potential role of JAK inhibitors in the management of COVID-19
Francesca Romana Spinelli et al.
Focus | Science Immunology Date: 8-May-2020 DOI: 10.1126/sciimmunol.abc5367

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Science Robotics

The potential of socially assistive robots during infectious disease outbreaks
Brian Scassellati and Marynel Vázquez
Research Article | Science Robotics Date: 15-Jul-2020 DOI: 10.1126/scirobotics.abc9014

Combating COVID-19—The role of robotics in managing public health and infectious diseases
Guang-Zhong Yang, Bradley J. Nelson, Robin R. Murphy, Howie Choset, Henrik Christensen, Steven H. Collins, Paolo Dario, Ken Goldberg, Koji Ikuta, Neil Jacobstein, Danica Kragic, Russell H. Taylor, Marcia McNutt
Editorial | Science Robotics Date: 25-Mar-2020 DOI: 10.1126/scirobotics.abb5589

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Science Signaling

COVID-19: All the wrong moves in all the wrong places
Christopher D. Barrett and Michael B. Yaffe
Editorial | Science Signaling Date: 15-Sep-2020 DOI: 10.1126/scisignal.abe4242

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Science Translational Medicine

Immune responses to SARS-CoV-2 infection in hospitalized pediatric and adult patients
Carl A. Pierce et al.
Research Article | Science Translational Medicine Date: 21-Sep-2020 DOI: 10.1126/scitranslmed.abd5487

We’re on our own
H. Holden Thorp
Editorial | Science Translational Medicine Date: 4-Sep-2020 DOI: 10.1126/scitranslmed.abe5793

A comparison of four serological assays for detecting anti-SARS-CoV-2 antibodies in human serum samples from different populations
Ludivine Grzelak et al.
Research Article | Science Translational Medicine Date: 17-Aug-2020 DOI: 10.1126/scitranslmed.abc3103

3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice
Athri D. Rathnayake et al.
Report | Science Translational Medicine Date: 3-Aug-2020 DOI: 10.1126/scitranslmed.abc5332

A colorimetric RT-LAMP assay and LAMP-sequencing for detecting SARS-CoV-2 RNA in clinical samples
Viet Loan Dao Thi et al.
Research Article | Science Translational Medicine  Date: 27-Jul-2020 DOI: 10.1126/scitranslmed.abc7075

An alphavirus-derived replicon RNA vaccine induces SARS-CoV-2 neutralizing antibody and T cell responses in mice and nonhuman primates
Jesse H. Erasmus et al.
Research Article | Science Translational Medicine Date: 20-Jul-2020 DOI: 10.1126/scitranslmed.abc9396

Using influenza surveillance networks to estimate state-specific prevalence of SARS-CoV-2 in the United States
Justin D. Silverman et al.
Report | Science Translational Medicine Date: 22-Jun-2020 DOI: 10.1126/scitranslmed.abc1126

Antibody signature mediated by SARS-CoV-2 spike protein immunogens in rabbits
Supriya Ravichandran et al.
Report | Science Translational Medicine Date: 8-Jun-2020 DOI: 10.1126/scitranslmed.abc3539

COVID-19 diagnostics in context
Ralph Weissleder et al.
Perspective | Science Translational Medicine Date: 3-Jun-2020 DOI: 10.1126/scitranslmed.abc1931

A rapidly deployable individualized system for augmenting ventilator capacity
Shriya Srinivasan et al.
Report | Science Translational Medicine Date: 18-May-2020 DOI: 10.1126/scitranslmed.abb9401

An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice
Timothy P. Sheahan, Amy C. Sims, Shuntai Zho, Rachel L. Graham, Andrea J. Pruijssers, Maria L. Agostini, Sarah R. Leist, Alexandra Schäfer, Kenneth H. Dinnon III, Laura J. Stevens, James D. Chappell, Xiaotao Lu, Tia M. Hughes, Amelia S. George, Collin S. Hill, Stephanie A. Montgomery, Ariane J. Brown, Gregory R. Bluemling, Michael G. Natchus, Manohar Saindane, Alexander A. Kolykhalov, George Painter, Jennifer Harcourt, Azaibi Tamin, Natalie J. Thornburg, Ronald Swanstrom, Mark R. Denison, Ralph S. Baric
Research Article | Science Translational Medicine Date: 6-Apr-2020 DOI: 10.1126/scitranslmed.abb5883

New coronavirus outbreak: Framing questions for pandemic prevention
Scott P. Layne, James M. Hyman, David M. Morens, Jeffrey K. Taubenberger
Editorial | Science Translational Medicine Date: 11-Mar-2020 DOI: 10.1126/scitranslmed.abb1469

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News from Science

Science's COVID-19 reporting is supported by the Heising-Simons Foundation and the Pulitzer Center.

Highlighted story: Why COVID-19 is more deadly in people with obesity—even if they’re young

To fight COVID-19, a young epidemiologist bridges the gulf between science and U.S. politics  Controversial ‘human challenge’ trials for

The line is forming for a COVID-19 vaccine. Who should be at the front?

Blood vessel attack could trigger coronavirus’ fatal ‘second phase’

How does coronavirus kill? Clinicians trace a ferocious rampage through the body, from brain to toes

Visit News from Science for more coronavirus coverage (or use our COVID-19 RSS news feed).

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Letters to the Editor

University–pharmacy partnerships for COVID-19
Vincent J. Venditto et al.
Letter to the Editor | Science Date: 18-Sep-2020 DOI: 10.1126/science.abe3339

Accumulation of plastic waste during COVID-19
Tanveer M. Adyel
Letter to the Editor | Science Date: 11-Sep-2020 DOI: 10.1126/science.abd9925

Support transgender scientists post–COVID-19
Shaun Turney et al.
Letter to the Editor | Science Date: 4-Sep-2020 DOI: 10.1126/science.abd8933

Controlling the coronavirus narrative
Nita Bharti
Letter to the Editor | Science Date: 14-Aug-2020 DOI: 10.1126/science.abd3662

Conservation needs a COVID-19 bailout
Robert A. McCleery et al.
Letter to the Editor | Science Date: 31-Jul-2020 DOI: 10.1126/science.abd2854

Extinct-in-the-wild species’ last stand
Amanda Trask et al.
Letter to the Editor | Science Date: 31-Jul-2020 DOI: 10.1126/science.abd4560

Nicaragua’s COVID-19 crisis demands a response
Jorge Huete-Pérez and John Hildebrand
Letter to the Editor | Science Date: 24-Jul-2020 DOI: 10.1126/science.abd4975

A community-led approach to COVID-19
Kyle A. Artelle et al.
Letter to the Editor | Science Date: 24-Jul-2020 DOI: DOI: 10.1126/science.abd2107

COVID-19 policies: Remember measles
Debarati Guha-Sapir et al.
Letter to the Editor | Science Date: 17-Jul-2020 DOI: 10.1126/science.abc8637

Restart science stronger after COVID-19
Alan I. Leshner
Letter to the Editor | Science Date: 17-Jul-2020 DOI: 10.1126/science.abd5780

Unnecessary hesitancy on human vaccine tests
Nir Eyal
Letter to the Editor | Science Date: 10-Jul-2020 DOI: 10.1126/science.abc8264

Response—Unnecessary hesitancy on human vaccine tests
Seema K. Shah et al.
Letter to the Editor | Science Date: 10-Jul-2020 DOI: 10.1126/science.abc9380

News from a postpandemic world
Joel Henrique Ellwanger et al.
Letter to the Editor | Science Date: 3-Jul-2020 DOI: 10.1126/science.abd1320

COVID-19's unsustainable waste management
Siming You et al.
Letter to the Editor | Science Date: 26-Jun-2020 DOI: 10.1126/science.abc7778

Pandemics’ historical role in creating inequality
Liliana M. Dávalos et al.
Letter to the Editor | Science Date: 19-Jun-2020 DOI: 10.1126/science.abc8953

Recent immigrants at increased pandemic risk
Pierre Galanaud and Anne Galanaud
Letter to the Editor | Science Date: 19-Jun-2020 DOI: 10.1126/science.abd1098

Aggregating data from COVID-19 trials
Elizabeth L. Ogburn et al.
Letter to the Editor | Science Date: 12-Jun-2020 DOI: 10.1126/science.abc8993

Tenure and promotion after the pandemic
Mala Htun
Letter to the Editor | Science Date: 5-Jun-2020 DOI: 10.1126/science.abc7469

Ease restrictions on U.S. blood donations
Chirag Vasavda et al.
Letter to the Editor | Science Date: 29-May-2020 DOI: 10.1126/science.abc2322

The precarious position of postdocs during COVID-19
M. Arslan Ahmed et al.
Letter to the Editor | Science Date: 29-May-2020 DOI: 10.1126/science.abc5143

COVID-19 recovery can benefit biodiversity
Ryan M. Pearson et al.
Letter to the Editor | Science Date: 22-May-2020 DOI: 10.1126/science.abc1430

COVID-19 spotlights medical diagnostics
Maurycy Jankowski et al.
Letter to the Editor | Science Date: 22-May-2020 DOI: 10.1126/science.abb8952

Impact of COVID-19 on academic mothers
F. Staniscuaski et al.
Letter to the Editor | Science Date: 15-May-2020 DOI: 10.1126/science.abc2740

Support early-career field researchers
D. W. Inouye et al.
Letter to the Editor | Science Date: 15-May-2020 DOI: 10.1126/science.abc1261

Preserve Global South's research capacity
D. Reidpath et al.
Letter to the Editor | Science Date: 15-May-2020 DOI: 10.1126/science.abc2677

Call for transparency of COVID-19 models
C. Michael Barton et al.
Letter to the Editor | Science Date: 1-May-2020 DOI: 10.1126/science.abb8637

Research opportunities in pandemic lockdown
Rajeev Saraswat, Divya Atri Saraswat
Letter to the Editor | Science Date: 30-Apr-2020 DOI: 10.1126/science.abc3372

Protect Indigenous peoples from COVID-19
Lucas Ferrante, Philip M. Fearnside
Letter to the Editor | Science Date: 17-Apr-2020 DOI: 10.1126/science.abc0073

Protecting older adults during social distancing
Ali Jawaid
Letter to the Editor | Science Date: 10-Apr-2020 DOI: 10.1126/science.abb7885

Disinfection threatens aquatic ecosystems
Hong Zhang et al.
Letter to the Editor | Science Date: 10-Apr-2020 DOI: 10.1126/science.abb8905

Permanently ban wildlife consumption
Nian Yang et al.
Letter to the Editor | Science Date: 27-Mar-2020 DOI: 10.1126/science.abb1938

Wildlife consumption ban is insufficient
Hongxin Wang et al.
Letter to the Editor | Science Date: 27-Mar-2020 DOI: 10.1126/science.abb6463

COVID-19 drives new threat to bats in China
Huabin Zhao
Letter to the Editor | Science Date: 27-Mar-2020 DOI: 10.1126/science.abb3088

Travel restrictions violate international law
Benjamin Mason Meier et al.
Letter to the Editor | Science Date: 27-Mar-2020 DOI: 10.1126/science.abb6950

Aggregated mobility data could help fight COVID-19
Caroline O. Buckee et al.
Letter to the Editor | Science Date: 23-Mar-2020 DOI: 10.1126/science.abb8021

Preventing COVID-19 prejudice in academia
Piotr Rzymski, Michał Nowicki
Letter to the Editor | Science Date: 20-Mar-2020 DOI: 10.1126/science.abb4870

Misguided drug advice for COVID-19
Garret A. FitzGerald
Letter to the Editor | Science Date: 20-Mar-2020 DOI: 10.1126/science.abb8034

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Book Reviews

Discounting lives
Audra J. Wolfe
Book Review | Science Date: 12-Jun-2020 DOI: 10.1126/science.abc0164

Tinctures of time and Schrödinger's virus
Luis Campos
Book Review | Science Date: 1-May-2020 DOI: 10.1126/science.abc1732

The other public health crisis
Joanna Schug
Book Review | Science Date: 1-May-2020 DOI: 10.1126/science.abb3582

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Blogs

Atlas shrugs
H. Holden Thorp
Blog post | Science Date: 18-Aug-2020

Modeling herd immunity
H. Holden Thorp, Valda Vinson, Caroline Ash
Blog post | Science Date: 23-Jun-2020

Guest blogs
H. Holden Thorp
Blog post | Science Date: 12-May-2020

Reading the pandemic data
Jeffrey M. Zacks and Steven L. Franconeri
Blog post | Science Date: 12-May-2020

The end of the handshake?
Cato T. Laurencin and Aneesah McClinton
Blog post | Science Date: 12-May-2020

Drawing the blueprint to a COVID-19 response
H. Holden Thorp
Blog post | Science Date: 27-Apr-2020

Expanding voices during the COVID-19 crisis
H. Holden Thorp
Blog post | Science Date: 7-Apr-2020

Adapting to the crisis
H. Holden Thorp
Blog post | Science Date: 3-Apr-2020

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Additional Content

Coronavirus Investigated video series: A deeper look at the concepts behind coronavirus research

Sponsored Science webinar: Coronavirus: A survival guide

Science Podcasts: Interviews with reporters and researchers on the latest coronavirus stories

Video: How diseases rise and fall with the seasons—and what it could mean for coronavirus

Science Facebook Live: How understanding SARS-CoV-2 structure is informing vaccine design and clinical trial