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Sickle-cell disease is a recessive genetic blood disorder characterized by red blood cells that assume an abnormal, rigid, sickle shape. Here healthy blood cells are seen along with diseased cells. Computer generated image.

Developing sickle cell drugs

Science Advances | Aug. 21, 2019

Science Picture Co/Science Source

Printed flat sheet that was assembled into a 3D triangulated structure. It exhibited sequential folding upon heating from (left to right) ambient temperature; to 100°C, where the LTNI LCE hinges actuated; and to 150°C, where the HTNI LCE hinges actuated

Soft robots shape-shift without tethers, thanks to these soft hinges

Science Robotics | Aug. 21, 2019

A. Kotikian et al./Science Robotics

Transmission electron micrograph of purified reticulocytes in mice with HSCs of the indicated genotypes treated with rapamycin or vehicle

Unclogging red blood cells

Science Translational Medicine | Aug. 21, 2019

Lechauve et al./Science Translational Medicine

The lower Ebre River (Catalonia, Spain) in 2009

Changing nutrients, changing rivers

Science | Aug. 15, 2019

IRTA

Image of a microphone speaker

NextGen VOICES: Ask a peer mentor

The image shows immunohistochemistry of breast tumors from taxane-treated mice for the glucose transporter Glut1 (red) and CD44 (green), a marker for the metabolic switch.

Metabolic remodeling for drug resistance

Science Signaling | Aug. 20, 2019

Goldman et al./Science Signaling

Mouse intestinal villi of a gut explant show scattered epithelial cells marked by green fluorescent protein.

Marching out of the crypt

Science | Aug. 15, 2019

D. KRNDIJA ET AL.

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