Forces in Development

INTRODUCTION—When gazing at the stages from embryo to adult, it is clear that a multitude of cell movements and deformations are at play to shape the folds, cavities, and appendages. How do these dynamic activities come about? [Read the full introduction]


From Science

Review

Developmental Pattern Formation: Insights from Physics and Biology

Dynamic interactions between morphogens and gene regulatory networks determine cell fate and tissue patterning.
Review

Knowing the Boundaries: Extending the Differential Adhesion Hypothesis in Embryonic Cell Sorting

Mechanobiology is applied to developmental biology to understand forces controlling cell sorting and compartmentalization.
Perspective

A Dynamical-Systems View of Stem Cell Biology

A theoretic perspective can be used to describe stem cell behavior.
Perspective

Physico-Genetic Determinants in the Evolution of Development

Physical processes mobilized by ancient genes in a multicellular context established animal form.
 
 
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[Cover image credit: Dr. Richard Kessel/Visuals Unlimited, Inc.; header image credit: Martin Behrndt, Stephan Grill and Carl-Philipp Heisenberg.]