Every year, crowning one scientific achievement as Breakthrough of the Year is no easy task, and 2012 was no exception. The year saw leaps and bounds in physics, along with significant advances in genetics, engineering, and many other areas. In keeping with tradition, Science’s editors and staff have selected a winner and nine runners-up, as well as highlighting the year’s top news stories and areas to watch in 2013.
This year's runners-up for Breakthrough of the Year underscore feats in engineering, genetics, and other fields that promise to change the course of science.
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