and its online companion sites offer a broad view of drug discovery issues, both scientific and practical, in a special collection
published 19 March 2004. In Science
, News, Viewpoint, and Review articles cover the roles of molecular biology, organic chemistry, and computer science in blazing
new trails in both drug design and drug delivery -- as well as the "blockbuster syndrome" that can sometimes hamstring progress
in drug discovery. The Signal Transduction Knowledge Environment
explores how signaling pathways offer promising drug discovery targets, in a series of Perspectives and a Review. The Science of Aging Knowledge Environment
examines drug discovery progress in a range of aging-related disorders, particularly neurodegenerative diseases. And Science's Next Wave
continues its March 2004 special series on careers in drug discovery.