In the 13 April 2007 issue, Science unveils the genome sequence of one of biology's most important model organisms -- the rhesus macaque monkey (Macaca mulatta). In Science, a Research Article and four Reports, as well as two News stories, detail the biomedical and evolutionary insights gained from the macaque genome, only the third primate genome to be completed after human and chimpanzee. Online, an interactive poster enhanced with images, discussions, and videos explores the significance of the rhesus macaque and its draft genome sequence to studies of primate biology and evolution. Accompanying the online feature is an educational resource for high school biology teachers, which includes teacher background information, a lesson plan, and student worksheet. [Note: All articles in the Science rhesus macaque special section, as well as the interactive poster and teaching resource, are free to all site visitors.]

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In Science

INTRODUCTION A Barrel of Monkey Genes  L. M. Zahn, B. R. Jasny, E. Culotta, and E. Pennisi Poster NEWS Boom Time for Monkey Research  E. Pennisi Genomicists Tackle the Primate Tree  E. Pennisi RESEARCH ARTICLE Evolutionary and Biomedical Insights from the Rhesus Macaque Genome  Rhesus Macaque Genome Sequencing and Analysis Consortium REPORTS Human-Specific Changes of Genome Structure Detected by Genomic Triangulation  R. A. Harris, J. Rogers, and A. Milosavljevic Mobile DNA in Old World Monkeys: A Glimpse Through the Rhesus Macaque Genome  K. Han et al. Demographic Histories and Patterns of Linkage Disequilibrium in Chinese and Indian Rhesus Macaques  R. D. Hernandez et al. Evolutionary Formation of New Centromeres in Macaque  M. Ventura et al.

ONLINE EXTRAS: Interactive Poster/Video We've put together a special interactive version of the Macaque Genome poster from the print Science, with larger-format images, additional text, and video interviews on the broad biomedical and evolutionary themes that the genome raises. There's also a special teaching resource to accompany the poster (see below). Teaching Resource Attention educators: To accompany this special issue and its interactive poster, we've created an educational resource for high school biology courses that includes background and context-setting material as well as a lesson plan and questions for students to consider while exploring the online poster. [More information on the teaching resource] SUBSCRIBE TO SCIENCE Join AAAS and receive a print subscription to Science, as well as online access to the full text of Science, Science Classic, and Science Express. Join today. REGISTER FOR FREE PARTIAL ACCESS Your free registration provides access to the full text of Science research articles at least one year old and published after 1996. You can also sign-up for weekly e-mail alerts from Science. Sign-up today.