How we understand gene expression and function -- as well as the mistakes in gene regulation that can lead to disease -- forms the topic of a special collection of articles in
Science and its online companion sites. In
Science, News, Review, and Viewpoint articles explore a variety of aspects of gene expression and its regulation, efforts to develop a complete "parts list" of the structural and functional elements of the human genome, and the promise of systems-based approaches to further the goal of predictive medicine. Articles in the
Signal Transduction Knowledge Environment offer insight into the dynamics of gene expression from a signaling perspective. The
Science of Aging Knowledge Environment looks at how microarrays and other genome-scale technologies are being applied to aging research. And the
Science Functional Genomics Web site features an online discussion on the future of microarrays, as well as links to additional resources on gene expression.
In 
