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Special Online Collection: Decision-Making

Jump to features in special collection:

Decision-MakingIn the 26 October 2007 issue, Science and its online companion Signal Transduction Knowledge Environment (STKE) examine the processes and structures that underlie decision-making -- from cellular choices to major life-changing decisions. Review articles in Science discuss the role of the frontopolar cortex in human cognition, a neuroeconomic approach to the study of social decision-making, the decision-making dysfunctions associated with psychiatric disorders, and advances in decision theory. In STKE, two Perspectives look at decision-making at the cellular level from the decision of a progenitor to become a neuron or a glial cell to the influence of potassium channels on cell metabolism and excitability.

In Science

INTRODUCTION

Decisions, Decisions... >
Peter Stern

REVIEWS

Anterior Prefrontal Function and the Limits of Human Decision-Making >
Etienne Koechlin, Alexandre Hyafil
Social Decision-Making: Insights from Game Theory and Neuroscience >
Alan G. Sanfey
Decision-Making Dysfunctions in Psychiatry—Altered Homeostatic Processing? >
Martin P. Paulus
Decision Theory: What “Should” the Nervous System Do? >
Konrad Körding

Also in this issue:

Editorial: On Neuroethics
Henry Greely

Two Therapies Release Different Brakes on Impulsive Behavior
Greg Miller

Report: Hold Your Horses: Impulsivity, Deep Brain Stimulation, and Medication in Parkinsonism
Michael J. Frank et al.

Report: Mnemonic Function of Lateral Prefrontal Cortex in Conflict-Induced Behavioral Adjustment
Farshad A. Mansouri et al.

On the Science Podcast

In the 26 October 2007 Science Podcast, host Robert Frederick interviews researcher Michael Frank on the effect of two therapies for Parkinson's disease -- L-dopa and deep brain stimulation -- on decision-making and impulsive behavior.

In Science's Signal Transduction Knowledge Environment

EDITORIAL GUIDE

Focus Issue: Decisions, Great and Small >
Elizabeth M. Adler and Nancy R. Gough
At the cellular level, neurons and their precursors face multiple decision points.

PERSPECTIVE

Neurons or Glia? Can SHP2 Know It All? >
Volkan Coskun, Jing Zhao, and Yi E. Sun
The tyrosine phosphatase SHP2 may help regulate the balance between neurogenesis and gliogenesis.

PERSPECTIVE

Alchemy in the Soup: Transforming Metabolic Signals to Excitability >
Colin G. Nichols
ATP-sensitive potassium channels link cell metabolism to excitability in various tissues.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)