Special Online Collection: Decision-Making

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Special Online Collection: Decision-Making

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In Science
Podcast
In STKE

In the 26 October 2007 issue, Science and its online companion Signal Transduction Knowledge Environment (STKE) examine the processes and structures that underlie decision-making -- from cellular choices to major life-changing decisions. Review articles in Science discuss the role of the frontopolar cortex in human cognition, a neuroeconomic approach to the study of social decision-making, the decision-making dysfunctions associated with psychiatric disorders, and advances in decision theory. In STKE, two Perspectives look at decision-making at the cellular level from the decision of a progenitor to become a neuron or a glial cell to the influence of potassium channels on cell metabolism and excitability.

In Science

On the Science Podcast

In the 26 October 2007 Science Podcast, host Robert Frederick interviews researcher Michael Frank on the effect of two therapies for Parkinson's disease -- L-dopa and deep brain stimulation -- on decision-making and impulsive behavior.

In Science's Signal Transduction Knowledge Environment

EDITORIAL GUIDE

Focus Issue: Decisions, Great and Small: Elizabeth M. Adler and Nancy R. Gough
At the cellular level, neurons and their precursors face multiple decision points.

PERSPECTIVE

Neurons or Glia? Can SHP2 Know It All?: Volkan Coskun, Jing Zhao, and Yi E. Sun
The tyrosine phosphatase SHP2 may help regulate the balance between neurogenesis and gliogenesis.

PERSPECTIVE

Alchemy in the Soup: Transforming Metabolic Signals to Excitability: Colin G. Nichols
ATP-sensitive potassium channels link cell metabolism to excitability in various tissues.