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Special Online Collection: Modeling the Mind

Jump to features in special collection:

Modeling the MindThis week, Science and its online companion sites the Signal Transduction Knowledge Environment (STKE) and ScienceCareers.org explore how scientists are using mathematical models and computer simulations to study and predict the behavior of the nervous system. In Science, News and Review articles look at the dynamics and computations of single neurons and their role within larger neural networks, models of high-level cognition, and new technologies inspired by theories of brain function and mathematical principles underlying human vision. Review and Perspective articles in STKE cast an eye on excitatory signaling in the brain. And a collection of articles on ScienceCareers.org focuses on career and funding opportunities in computational neuroscience.

In Science

INTRODUCTION

Of Bytes and Brains >
P. Stern and J. Travis

NEWS

An Enterprising Approach to Brain Science >
G. Miller
Vision’s Grand Theorist >
I. Wickelgren

REVIEWS

Modeling Single-Neuron Dynamics and Computations: A Balance of Detail and Abstraction >
A. V. M. Herz, T. Gollisch, C. K. Machens, D. Jaeger
Neuronal Computations with Stochastic Network States >
A. Destexhe and D. Contreras
Biologically Based Computational Models of High-Level Cognition >
R. C. O’Reilly

Also in this issue:

Editorial: Prying Open the Black Box
F. Bloom

Book Review: A Case for the Moral Organ?
M. R. Waldmann

Book Review: The Powers of Rhythm
P. Fries

Book Review: From the Dark Side to the Bright Side of Drug Addiction
B. J. Everitt

Book Review: How Does the Brain Deal with the Social World?
S. J. Blakemore

In Science's Signal Transduction Knowledge Environment

EDITORIAL GUIDE

Focus Issue: Exciting Times for Signaling in the Brain >
E. M. Adler
Glutamate receptors are central to brain function and pathology.

PERSPECTIVE

D-Serine Regulation of NMDA Receptor Activity >
H. Wolosker
Does D-serine released from neurons and glia play distinct roles in regulating NMDA receptor activity?

REVIEWS

A Unified Model of the Presynaptic and Postsynaptic Changes During LTP at CA1 Synapses >
J. Lisman and S. Raghavachari
A structural model for LTP accounts for seemingly contradictory results.
Molecular Signaling Mechanisms Underlying Epileptogenesis >
J. O. McNamara, Y. Z. Huang, and A. S. Leonard
Does increased calcium in dendritic spines play a key role in epileptogenesis?

In ScienceCareers.org

FEATURE INDEX

Special Feature: Careers in Computational Neuroscience
A. Kotok
Career and funding opportunities are growing for researchers who combine neuroscience with informatics and engineering.

ARTICLES

Europe: Leading the Blue Brain Project
E. Pain
Felix Schürmann, a 29-year-old German postdoc, leads the Blue Brain Project, a collaboration between IBM and the Brain Mind Institute in Switzerland.
Canada: Neural Computing at Waterloo
A. Fazekas
Established in 2001, the computational neuroscience research group at the University of Waterloo is planning to hire new faculty and getting set to open up its own centre.
Global: Financing Your Research in Computational Neuroscience
A. Kotok
Science Careers surveys several American sources of computational neuroscience research funding in the public and private-nonprofit sectors.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)