In the 5 October 2007 issue, Science and its online companion Signal Transduction Knowledge Environment (STKE) team up to explore select areas of current cell signaling research. Perspective articles in Science describe the mechanisms that underlie leading causes of life-threatening diseases such as cancer and heart disease, control excessive stimulation of the immune system, and regulate development and a range of environmental responses in plants. Each article is coupled to one or more Connections Maps in STKE's Database of Cell Signaling. These graphical depictions of signaling pathways and their components include links to relevant literature, data, and background information.

In Science and Science's Signal Transduction Knowledge Environment