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Systems-Level Brain Development

Jump to Features in
This Special Collection:

In Science Magazine
In Science's STKE
In Science's SAGE KE
In Science's Next Wave
In a collection of articles published with the 4 November 2005 issue, Science Magazine and its online companion sites focus on the analysis of brain development at a systems level, linking cell biology with psychiatry. A special section in Science includes News, Review, and Viewpoint articles on topic such as cortical plasticity and patterning, language acquisition, and gender differences in the brain. The Signal Transduction Knowledge Environment features a special focus issue on the signaling and molecular changes that govern in synaptic plasticity; the Science of Aging Knowledge Environment includes a Perspective on working memory and selective attention in cognitive aging. And Science's Next Wave offers a special feature on careers in neuroscience research.

 

In Science
INTRODUCTION

Neuroscience: Systems-Level Brain Development
P. Stern and P. J. Hines

NEWS
Friendly Faces and Unusual Minds
Y. Bhattacharjee

REVIEWS
Patterning and Plasticity of the Cerebral Cortex
M. Sur and J. L. R. Rubenstein

Map Plasticity in Somatosensory Cortex
D. E. Feldman and M. Brecht
[Full-text access is available to AAAS members and to institutional subscribers to the online version of Science]

In STKE

EDITORIAL GUIDE

Focus Issue -- Memories of Signals Past: Plastic Changes in Nervous System Function
E. M. Adler and N. R. Gough
Molecular changes underlie synaptic plasticity in response to physiological or pathological stimuli.
PERSPECTIVES

Endocannabinoid Identification in the Brain -- Studies of Breakdown Lead to Breakthrough, and There May Be NO Hope
B. E. Alger
How do endocannabinoids mediate depolarizationinduced suppression of inhibition?
Hijacking the ERK Signaling Pathway -- Mycobacterium leprae Shuns MEK to Drive the Proliferation of Infected Schwann Cells
L. A. Noon and A. C. Lloyd
M. leprae subverts the normal mechanisms regulating Schwann cell proliferation.

REVIEW

The "Ups and Downs" of Signaling Cascades in Addiction
D. Ron and R. Jurd
Elucidation of signaling cascades involved in addiction may lead to new therapeutic approaches.
TEACHING RESOURCE

Long-Term Potentiation -- Mechanisms of Induction and Maintenance
R. D. Blitzer
Prepare a graduate-level class about the signals responsible for LTP induction and maintenance.
[Full-text access may require a separate subscription to STKE]

In Science's SAGE KE


PERSPECTIVES

Keeping Priorities -- The Role of Working Memory and Selective Attention in Cognitive Aging
J. W. de Fockert
Elderly have trouble distinguishing relevant and irrelevant information.


[Full-text access may require a separate subscription to SAGE KE]

In Science's Next Wave

FEATURE INDEX

Global: Careers in Neuroscience Research
A. Forde
Next Wave profiles neuroscientists whose passion and dedication has led to outstanding research.
ARTICLES

Global/U.S.: Crossroads in Neuroscience
J. Kling
Two young scientists are studying brain imaging and behavior and the molecular cues that guide neuronal growth.
Global/Canada: Getting Wired -- Pathway of a Neuroscientist
A. Fazekas
Edward Ruthazer of McGill University's Montreal Neurological Institute talks about his fulfilling career.
Global/Europe: The Biology of Memory
A. Forde
Understanding processes involving memory has been the basis of neuroscientist Edvard Moser's career, now director of a research institute in Norway.



Global/Europe: Neurology in the Lab, and at Patients' Bedsides
E. Pain
Neurology was Diego Centonze's second choice, but it opened up a whole new world of research.
Global/MiSciNet: Investigating the Neural and Vascular Consequences of Stroke
R. Arnette
Byron Ford has a varied background that enabled him to carve out a unique niche in stroke research.
Global/GrantsNet: Funding Opportunities in Neuroscience
Edited by S.Martin
GrantsNet offers a sampling of funding opportunities for neuroscience research.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)