The coffee genome has finally been sequenced, and it’s revealing some insights into how one of the world’s favorite drinks got its buzz. Compared with other plant genomes such as grape’s, the coffee genome has expanded the family of genes that include those that code for enzymes involved in caffeine production, researchers report online today in Science. There are 23 new genes found only in coffee, the group finds. These genes are different from the caffeine-related genes in chocolate, indicating that the ability to produce caffeine evolved at least twice. This isn’t just the first published coffee genome; it’s also the first in its 11,000 or so species family, which includes milkweeds, periwinkles, and the species that supplies quinine. Although the genomes of many groups have undergone duplications thought to make possible their diversification into different shapes and sizes, the researchers found no such expansion in the coffee group. Instead they suggest that the duplication of individual genes, including the caffeine ones, spurred innovations.