25 March 2016
Vol. 351, No. 6280, Pages 1405-a-1494
Grisly find suggests Bronze Age northern Europe was more organized—and violent—than thought.
DNA released from obesity-induced degenerated adipocytes stimulates inflammation in adipose tissue and insulin resistance.
China’s forest cover exhibited a positive trend that was significantly related with the implementation of a national conservation policy.
The San Andreas and San Jacinto faults likely slipped together in a single earthquake in 1812 and are capable of doing so again.
Exquisitely preserved fossil lizards from 99-million-year-old Burmese amber provide new insights into paleotropical diversity.
A new type of plasmonic nanostructures with topologically protected metallic shells and high–refractive index dielectric cores.
Atomic resolution core-level spectroscopy in the TEM reveals the hole distribution among chains and ladders in Sr3Ca11Cu24O41.
23 March 2016
Vol. 8, No. 331, Pages 331ed3-331ra41
Fibrillar carbon nanotubes simultaneously deliver two small interfering RNAs, which safely prevent acute kidney injury and prolong survival in mice.
MDSCs promote TH17 differentiation and systemic lupus erythematosus via arginase-1 production in patients and humanized mice.
Augmenting the heat shock response with arimoclomol ameliorates pathology in cellular and animal models of inclusion body myositis.
ROS deficiency promotes proinflammatory T cells in rheumatoid arthritis.
A shunting of glucose metabolism to the pentose phosphate pathway in rheumatoid arthritis T cells causes exhaustion of oxidants, enhanced cell proliferation, and differentiation toward the T helper 1 (TH1) and TH17 programs (Yang et al., this issue).
A new public-private partnership with the NIH hopes to address the surplus of high-quality biomedical research applications that merit funding.
22 March 2016
Vol. 9, No. 420, Pages ec65-re3
A GRK2-derived peptide inhibits pathological cardiac hypertrophy and may prevent heart failure.
Identifying conformational interactions between kinases and their substrates may improve the development and clinical success of kinase inhibitors.
