Atom probe yields geologically meaningful ages from nanoscale Pb-enriched dislocation loops in discordant zircon.
Nearly ballistic carbon nanotube array transistors are realized with current densities outmatching conventional semiconductors.
A dual role of the C9ORF72/SMCR8-containing complex in autophagy initiation and autophagic flux.
We design a self-powered materials system that transduces chemical, mechanical, and electrical energy to perform computation.
Comprehensive analysis of the lncRNA landscape in breast cancers and its relationship with key clinical features and functional pathways.
A novel facile strategy was developed to synthesize MgO nanocrystals for producing H through photodecomposing methanol.
Pediatric HIV patients who do not rapidly develop AIDS are shown to have immunological features similar to nonhuman primates that experience nonpathogenic SIV infection.
A bioactive lipokine promotes metabolic resilience of organelles and limits the progression of atherosclerosis.
A new, mechanically elastic biomaterial can be custom 3D-printed, is surgically friendly, and promotes robust bone regeneration.
Angiopoietin-1 is dysregulated in pediatric severe malaria, and targeting it prevents vascular dysfunction and death in a mouse model of cerebral malaria.
A subset of HIV-infected children shows an unusually benign course of infection that recapitulates key immunological aspects of the natural SIV infection of sooty mangabeys (Muenchhoff et al.).
Vascular stiffness drives glutaminase expression, promoting anaplerosis necessary for development of pulmonary hypertension.
Blocking tumor-derived cytokine signaling in dendritic cells enables engineered dendritic cells to function as an antitumor vaccine.
Two soluble binding proteins that differ in inhibitory ability and abundance fine-tune signaling by the cytokine interleukin-22.
The NF-κB subunit RelB determines whether inhibitory or transcriptionally active complexes are formed during noncanonical signaling.
Dying tumor cells release potassium ions that suppress the activity of tumor-infiltrating T cells.
Accumulation of the metabolite fumarate induces epigenetic changes that promote the epithelial-to-mesenchymal transition.
The kinase PKA phosphorylates and inactivates the NLRP3 inflammasome to restrain inflammation.
Radiotherapy and immunotherapy cooperate to generate antitumor immune responses for therapeutic gain.
RORα contributes to the profibrotic response in the gut in a mouse model of infection-induced gut inflammation.
Individuals heterozygous for HLA haplotypes have increased NK cell diversity because of distinct education pathways.
CD69 on activated T cells interacts with Myl9/12 expressed in inflamed airways, establishing tissue inflammation.
A secreted bacterial protein protects worms and mice from Salmonella pathogenesis.