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Science Functional Genomics
Research

Molecular Evolution

Viewpoint: Evolution of the Protein Repertoire
Cyrus Chothia, Julian Gough, Christine Vogel, and Sarah A. Teichmann
Science, 13 June 2003, p. 1701-1703
[Abstract] [Full Text]

Brevia: Hybrid Origin of SIV in Chimpanzees
Elizabeth Bailes et al.
Science, 13 June 2003, p. 1713
[Full Text]

Sex-Dependent Gene Expression and Evolution of the Drosophila Transcriptome
José M. Ranz, Cristian I. Castillo-Davis, Colin D. Meiklejohn, and Daniel L. Hartl
Science, 13 June 2003, p. 1742-1745
[Abstract] [Full Text]

Brevia: Eukaryotic Intron Loss
Tobias Mourier and Daniel C. Jeffares
Science, 30 May 2003, p. 1393
[Full Text]

Stress-Induced Mutagenesis in Bacteria
Ivana Bjedov et al.
Science, 30 May 2003, p. 1404-1409
[Abstract] [Full Text]

Perspective: MICROBIOLOGY AND EVOLUTION:
Modulating Mutation Rates in the Wild

Susan M. Rosenberg and P. J. Hastings
Science, 30 May 2003, p. 1382-1383
[Summary] [Full Text]

Diverse Plant and Animal Genetic Records from Holocene and Pleistocene Sediments
Eske Willerslev et al.
Science, 2 May 2003, p. 791-795; published online April 17, 2003; 10.1126/science.1084114
[Abstract] [Full Text]

Balancing Selection at the Prion Protein Gene Consistent with Prehistoric Kurulike Epidemics
Simon Mead et al.
Science, 25 April 2003, p. 640-643; published online April 10, 2003; 10.1126/science.1083320
[Abstract] [Full Text]

News: GENE EVOLUTION:
Cannibalism and Prion Disease May Have Been Rampant in Ancient Humans

Elizabeth Pennisi
Science, 11 April 2003, p. 227-228
[Summary] [Full Text]

Early Origin and Recent Expansion of Plasmodium falciparum
Deirdre A. Joy et al.
Science, 11 April 2003, p. 318-321
[Abstract] [Full Text]

Chromosomal Speciation and Molecular Divergence--Accelerated Evolution in Rearranged Chromosomes
Arcadi Navarro and Nick H. Barton
Science, 11 April 2003, p. 321-324
[Abstract] [Full Text]

Perspective: EVOLUTION:
Chromosomal Speciation in Primates

Loren H. Rieseberg and Kevin Livingstone
Science, 11 April 2003, p. 267-268
[Summary] [Full Text]

Role of Mobile DNA in the Evolution of Vancomycin-Resistant Enterococcus faecalis
I. T. Paulsen et al.
Science, 28 March 2003, p. 2071-2074
[Abstract] [Full Text]

A Genomic View of the Human-Bacteroides thetaiotaomicron Symbiosis
Jian Xu et al.
Science, 28 March 2003, p. 2074-2076
[Abstract] [Full Text]

Perspective: MICROBIOLOGY:
The Thin Line Between Gut Commensal and Pathogen

Michael S. Gilmore and Joseph J. Ferretti
Science, 28 March 2003, p. 1999-2002
[Summary] [Full Text]

The Effects of Cenozoic Global Change on Squirrel Phylogeny
John M. Mercer and V. Louise Roth
Science, 7 March 2003, p. 1568-1572; published online February 20, 2003; 10.1126/science.1079705
[Abstract] [Full Text]

Traces of Human Migrations in Helicobacter pylori Populations
Daniel Falush et al.
Science, 7 March 2003, p. 1582-1585
[Abstract] [Full Text]

Perspective: MICROBIOLOGY:
Stomachs Out of Africa

Brian G. Spratt
Science, 7 March 2003, p. 1528-1529
[Summary] [Full Text]

Perspective: GENOMICS:
Molecular Prodigality

Dennis Bray
Science, 21 February 2003, p. 1189-1190
[Summary] [Full Text]

An Evolutionary Advantage of Haploidy in Large Yeast Populations
Clifford Zeyl, Thomas Vanderford, and Michele Carter
Science, 24 January 2003, p. 555-558
[Abstract] [Full Text]

Perspective: EVOLUTION:
Haploid Superiority

Duncan Greig and Michael Travisano
Science, 24 January 2003, p. 524-525
[Summary] [Full Text]

The Cellular and Molecular Origins of Beak Morphology
R. A. Schneider and J. A. Helms
Science, 24 January 2003, p. 565-568
[Abstract] [Full Text]

Perspective: DEVELOPMENT:
The Bills of Qucks and Duails

Paul Trainor
Science, 24 January 2003, p. 523-524
[Summary] [Full Text]

Recent Expansion of Toxoplasma Through Enhanced Oral Transmission
C. Su et al.
Science, 17 January 2003, p. 414-416
[Abstract] [Full Text]

Perspective: PARASITOLOGY:
A Game of Cat and Mouth

Sarah K. Volkman and Daniel L. Hartl
Science, 17 January 2003, p. 353-354
[Summary] [Full Text]

Book Review: HISTORY OF LIFE:
Just How Pregnant Is the Universe?

Antonio Lazcano
Science, 17 January 2003, p. 347-348
[Summary] [Full Text]

Genetic Structure of Human Populations
Noah A. Rosenberg et al.
Science, 20 December 2002, p. 2381-2385
[Abstract] [Full Text]

Perspective: HUMAN GENETICS:
Mapping Human History

Mary-Claire King and Arno G. Motulsky
Science, 20 December 2002, p. 2342-2343
[Summary] [Full Text]

Book Review: DEVELOPMENT:
Evo-Devo Branches Out

Vivian F. Irish
Science, 13 December 2002, p. 2135-2136
[Summary] [Full Text]

Genetic Evidence for an East Asian Origin of Domestic Dogs
Peter Savolainen, Ya-ping Zhang, Jing Luo, Joakim Lundeberg, and Thomas Leitner
Science, 22 November 2002, p. 1610-1613
[Abstract] [Full Text]

Ancient DNA Evidence for Old World Origin of New World Dogs
Jennifer A. Leonard et al.
Science, 22 November 2002, p. 1613-1616
[Abstract] [Full Text]

News Focus: CANINE EVOLUTION:
A Shaggy Dog History

Elizabeth Pennisi
Science, 22 November 2002, p. 1540-1542
[Summary] [Full Text]

Whole-Genome Analysis of Photosynthetic Prokaryotes
Jason Raymond, Olga Zhaxybayeva, J. Peter Gogarten, Sveta Y. Gerdes, and Robert E. Blankenship
Science, 22 November 2002, p. 1616-1620
[Abstract] [Full Text]

News: EVOLUTIONARY BIOLOGY:
Bacteria Shared Photosynthesis Genes

Elizabeth Pennisi
Science, 22 November 2002, p. 1538-1539
[Summary] [Full Text]

Sperm-Female Coevolution in Drosophila
Gary T. Miller and Scott Pitnick
Science, 8 November 2002, p. 1230-1233
[Abstract] [Full Text]

Specification of Jaw Subdivisions by Dlx Genes
Michael J. Depew, Thomas Lufkin, and John L. R. Rubenstein
Science, 11 October 2002, p. 381-385; published online August 22, 2002; 10.1126/science.1075703
[Abstract] [Full Text]

Perspective: EVOLUTION:
Jaws of the Fates

Georgy Koentges and Toshiyuki Matsuoka
Science, 11 October 2002, p. 371-373
[Summary] [Full Text]

Viewpoint: Speciation Within Anopheles gambiae-- the Glass Is Half Full
A. della Torre et al.
Science, 4 October 2002, p. 115-117
[Abstract] [Full Text]

Evolution of Autoantibody Responses via Somatic Hypermutation Outside of Germinal Centers
Jacqueline William, Chad Euler, Sean Christensen, and Mark J. Shlomchik
Science, 20 September 2002, p. 2066-2070
[Abstract] [Full Text]

Perspective: IMMUNOLOGY:
Autoreactive B Cells Migrate into T Cell Territory

Yang-Xin Fu and Ursula Storb
Science, 20 September 2002, p. 2006-2008
[Summary] [Full Text]

Identification of a DNA Nonhomologous End-Joining Complex in Bacteria
Geoffrey R. Weller et al.
Science, 6 September 2002, p. 1686-1689
[Abstract] [Full Text]

Recent Segmental Duplications in the Human Genome
Jeffrey A. Bailey et al.
Science, 9 August 2002, pp. 1003-1007
[Abstract] [Full Text]

Perspective: GENOMICS:
Gene Duplication and Evolution

Michael Lynch
Science, 9 August 2002, pp. 945-947
[Summary] [Full Text]

Evolution of the Gene Network Underlying Wing Polyphenism in Ants
E. Abouheif and G.A. Wray
Science, 12 July 2002, pp. 249-252
[Abstract] [Full Text]

Perspective: DEVELOPMENT:
Sociogenomics Takes Flight

G.E. Robinson
Science, 12 July 2002, pp. 204-205
[Summary] [Full Text]

Rooting the Eukaryote Tree by Using a Derived Gene Fusion
A. Stechmann and T. Cavalier-Smith
Science, 5 July 2002, pp. 89-91
[Abstract] [Full Text]

50 Million Years of Genomic Stasis in Endosymbiotic Bacteria
I. Tamas, L. Klasson, B. Canback, K. Naslund, A.-S. Eriksson, J.J. Wernegreen, J.P. Sandstrom, N.A. Moran, S.G.E. Anderson
Science, 28 June 2002, pp. 2376-2379
[Abstract] [Full Text]

Perspective: ORIGIN OF LIFE:
Some Like It Hot, But Not the First Biomolecules

Jeffrey L. Bada and Antonio Lazcano
Science, 14 June 2002, pp. 1982-1983
[Summary] [Full Text]

Hybridization and the Evolution of Reef Coral Diversity
Steven V. Vollmer and Stephen R. Palumbi
Science, 14 June 2002, pp. 2023-2025
[Abstract] [Full Text]

News: ECOLOGY:
A Coral by Any Other Name . . .

Elizabeth Pennisi
Science, 14 June 2002, pp. 1949-1950
[Summary] [Full Text]

Prehistoric Decline of Genetic Diversity in the Nene
Ellen E. Paxinos et al.
Science, 7 June 2002, pp. 1827
[Full Text]

The Structure of Haplotype Blocks in the Human Genome
Stacey B. Gabriel et al.
Science, 21 June 2002, p. 2225; published online May 23, 2002, 10.1126/science.1069424
[Abstract] [Full Text]

News: GENOMICS:
New Mapping Project Splits the Community

Jennifer Couzin
Science, 24 May 2002, pp. 1391-1393
[Summary] [Full Text]

Evidence of HIV-1 Adaptation to HLA-Restricted Immune Responses at a Population Level
Corey B. Moore et al.
Science, 24 May 2002, pp. 1439-1443
[Abstract] [Full Text]

Perspective: HIV/AIDS:
HLA Leaves Its Footprints on HIV

Andrew McMichael and Paul Klenerman
Science, 24 May 2002, pp. 1410-1411
[Summary] [Full Text]

Pyrrolysine Encoded by UAG in Archaea: Charging of a UAG-Decoding Specialized tRNA
Gayathri Srinivasan, Carey M. James, and Joseph A. Krzycki
Science, 24 May 2002, pp. 1459-1462
[Abstract] [Full Text]

A New UAG-Encoded Residue in the Structure of a Methanogen Methyltransferase
Bing Hao et al.
Science, 24 May 2002, pp. 1462-1466
[Abstract] [Full Text]

Perspective: BIOCHEMISTRY:
The 22nd Amino Acid

John F. Atkins and Ray Gesteland
Science, 24 May 2002, pp. 1409-1410
[Summary] [Full Text]

Review: Merging Genomes with Geochemistry in Hydrothermal Ecosystems
Anna-Louise Reysenbach and Everett Shock
Science, 10 May 2002, p. 1077-1082
[Abstract] [Full Text]

Evolutionary Rate in the Protein Interaction Network
Hunter B. Fraser, Aaron E. Hirsh, Lars M. Steinmetz, Curt Scharfe, and Marcus W. Feldman
Science, 26 April 2002, pp. 750-752
[Abstract] [Full Text]

African Pastoralism: Genetic Imprints of Origins and Migrations
Olivier Hanotte et al.
Science, 12 April 2002, pp. 336-339
[Abstract] [Full Text]

News: ARCHAEOLOGY:
Early Cowboys Herded Cattle in Africa

Erik Stokstad
Science, 12 April 2002, pp. 236
[Summary] [Full Text]

Intra- and Interspecific Variation in Primate Gene Expression Patterns
Wolfgang Enard et al.
Science, 12 April 2002, pp. 340-343
[Abstract] [Full Text]

News: PRIMATE EVOLUTION:
Gene Activity Clocks Brain's Fast Evolution

Elizabeth Pennisi
Science, 12 April 2002, pp. 233-235
[Summary] [Full Text]

The Interaction of Alba, a Conserved Archaeal Chromatin Protein, with Sir2 and Its Regulation by Acetylation
Stephen D. Bell et al.
Science, 5 April 2002, pp. 148-151
[Abstract] [Full Text]

Dynamics of Pleistocene Population Extinctions in Beringian Brown Bears
I. Barnes et al.
Science, 22 March 2002, pp. 2267-2270
[Abstract] [Full Text]

Rates of Evolution in Ancient DNA from Adélie Penguins
D. M. Lambert et al.
Science, 22 March 2002, pp. 2270-2273
[Abstract] [Full Text]

News: EVOLUTIONARY BIOLOGY:
Ancient DNA Untangles Evolutionary Paths

Elizabeth Pennisi
Science, 22 March 2002, pp. 2197
[Summary] [Full Text]

Extensive Fungal Diversity in Plant Roots
Philippe Vandenkoornhuyse et al.
Science, 15 March 2002, p. 1683
[Full Text]

Flight of the Dodo
Beth Shapiro et al.
Science, 1 March 2002, p. 1683
[Full Text]

Nucleotide Variation Along the Drosophila melanogaster Fourth Chromosome
Wen Wang, Kevin Thornton, Andrew Berry, and Manyuan Long
Science, 4 January 2002, p. 134-137
[Abstract] [Full Text]

Blocks of Limited Haplotype Diversity Revealed by High-Resolution Scanning of Human Chromosome 21
Nila Patil et al.
Science, 23 November 2001, pp. 1719-1723
[Abstract] [Full Text]

Sexual Recombination and the Power of Natural Selection
William R. Rice and Adam K. Chippindale
Science, 19 October 2001, pp. 555-559
[Abstract] [Full Text]

Perspective: GENETICS AND EVOLUTION:
Come Fly, and Leave the Baggage Behind

Richard E. Lenski
Science, 19 October 2001, pp. 533-534
[Summary] [Full Text]

Genomic and Genetic Definition of a Functional Human Centromere
Mary G. Schueler, Anne W. Higgins, M. Katharine Rudd, Karen Gustashaw, and Huntington F. Willard
Science, 5 October 2001, pp. 109-115
[Abstract] [Full Text]

Perspective: GENETICS:
Closing In on the Centromere

Elizabeth Pennisi
Science, 5 October 2001, pp. 30-31
[Summary] [Full Text]

Genetic Evidence for Two Species of Elephant in Africa
A.L. Roca et al.
Science, 24 August 2001, p. 1473-1477
[Abstract] [Full Text]

News: ECOLOGY:
African Elephant Species Splits in Two

Gretchen Vogel
Science, 24 August 2001, p. 1414
[Summary] [Full Text]

Haplotype Diversity and Linkage Disequilibrium at Human G6PD: Recent Origin of Alleles That Confer Malarial Resistance
Sarah A. Tishkoff et al.
Science, 20 July 2001, p. 455-462
[Abstract] [Full Text]

Perspective: MALARIA:
Protecting Against Bad Air

L. Luzzatto and R. Notaro
Science, 20 July 2001, p. 442-443
[Summary] [Full Text]

Recent Origin of Plasmodium falciparum from a Single Progenitor
Sarah K. Volkman et al.
Science, 20 July 2001, pp. 482-484
[Abstract] [Full Text]

News: INFECTIOUS DISEASES:
Malaria's Beginnings: On the Heels of Hoes?

Elizabeth Pennisi
Science, 20 July 2001, p. 416-417
[Summary] [Full Text]

Haplotype Variation and Linkage Disequilibrium in 313 Human Genes
J. C. Stephens et al.
Science, 20 July 2001, p. 489-493
[Abstract] [Full Text]

Molecular Evolution of Protein Atomic Composition
P. Baudoin-Cornu, Y. Surdin-Kerjan, P. Marlière, and D. Thomas
Science, 13 July 2001, p. 297-300
[Abstract] [Full Text]

Review: Evolutionary Dynamics of Plant R-Genes
Joy Bergelson, Martin Kreitman, Eli A. Stahl, and Dacheng Tian
Science, 22 June 2001, p. 2281-2284
[Abstract] [Full Text]

Microbial Genes in the Human Genome: Lateral Transfer or Gene Loss?
Steven L. Salzberg, Owen White, Jeremy Peterson, and Jonathan A. Eisen
Science, 8 June 2001, p. 1903-1906
[Abstract] [Full Text]

Perspective: GENOMICS:
Are There Bugs in Our Genome?

Jan O. Andersson, W. Ford Doolittle, and Camilla L. Nesbø
Science, 8 June 2001, p. 1848-1850
[Summary] [Full Text]

Perspective: MOLECULAR BIOLOGY AND EVOLUTION:
Can Genes Explain Biological Complexity?

E. Szathmáry, F. Jordán, C. Pál
Science, 18 May 2001, p. 1315-1316
[Summary] [Full Text]

Viewpoint: Genes Lost and Genes Found: Evolution of Bacterial Pathogenesis and Symbiosis
H. Ochman and N. A. Moran
Science, 11 May 2001, p. 1096-1099
[Abstract] [Full Text]

African Origin of Modern Humans in East Asia: A Tale of 12,000 Y Chromosomes
Y. Ke et al.
Science, 11 May 2001, p. 1151-1153
[Abstract] [Full Text]

News: HUMAN ANTHROPOLOGY:
Modern Men Trace Ancestry to African Migrants

A. Gibbons
Science, 11 May 2001, p. 1051-1052
[Summary] [Full Text]

Cooperation and Competition in the Evolution of ATP-Producing Pathways
T. Pfeiffer, S. Schuster, S. Bonhoeffer
Science, 20 April 2001, p. 504-507
[Abstract] [Full Text]

Extreme Diversity, Conservation, and Convergence of Spider Silk Fibroin Sequences
J. Gatesy, C. Hayashi, D. Motriuk, J. Woods, R. Lewis
Science, 30 March 2001, p. 2603-2606
[Abstract] [Full Text]

Costs and Benefits of High Mutation Rates: Adaptive Evolution of Bacteria in the Mouse Gut
A. Giraud et al.
Science, 30 March 2001, p. 2606-2608
[Abstract] [Full Text]

Review: Genealogical and Evolutionary Inference with the Human Y Chromosome
M. P. H. Stumpf and D. B. Goldstein
Science, 2 March 2001, p. 1738-1742
[Abstract] [Full Text]

Review: Genetic Clues to Dispersal in Human Populations: Retracing the Past from the Present
R. L. Cann
Science, 2 March 2001, p. 1742-1748
[Abstract] [Full Text]

Molecular and Morphological Supertrees for Eutherian (Placental) Mammals
F.-G. R. Liu et al.
Science, 2 March 2001, p. 1786-1790
[Abstract] [Full Text]

Perspective: PHYLOGENETICS:
Which Mammalian Supertree to Bark Up?

M. S. Springer and W. W. deJong
Science, 2 March 2001, p. 1709-1712
[Summary] [Full Text]

Structure of a Bag/Hsc70 Complex: Convergent Functional Evolution of Hsp70 Nucleotide Exchange Factors
H. Sondermann et al.
Science, 23 February 2001, p. 1553-1557
[Abstract] [Full Text]

Birth of Two Chimeric Genes in the Hominidae Lineage
Anouk Courseaux and Jean-Louis Nahon
Science, 16 February 2001, p. 1293-1297
[Abstract] [Full Text]

Review: Principles for the Buffering of Genetic Variation
J. L. Hartman IV, B. Garvik, L. Hartwell
Science, 9 February 2001, p. 1001-1004
[Abstract] [Full Text]

Chromosomal Effects of Rapid Gene Evolution in Drosophila melanogaster
D. Nurminsky, D. DeAguiar, C. D. Bustamante, and D. L Hartl
Science, 5 January 2001, p. 128-131
[Abstract] [Full Text]

The Origins of Genomic Duplications in Arabidopsis
Todd J. Vision, Daniel G. Brown, and Steven D. Tanksley
Science, 15 December 2000, p. 2114-2117
[Abstract] [Full Text]

The Evolutionary Fate and Consequences of Duplicate Genes
Michael Lynch and John S. Conery
Science, 10 November 2000, p. 1151-1155
[Abstract] [Full Text]

News: EVOLUTIONARY BIOLOGY:
Twinned Genes Live Life in the Fast Lane

Elizabeth Pennisi
Science, 10 November 2000, p. 1065-1066
[Summary] [Full Text]

A Kingdom-Level Phylogeny of Eukaryotes Based on Combined Protein Data
Sandra L. Baldauf, A. J. Roger, I. Wenk-Siefert, and W. F. Doolittle
Science, 3 November 2000, p. 972-977
[Abstract] [Full Text]

High Direct Estimate of the Mutation Rate in the Mitochondrial Genome of Caenorhabditis elegans
Dee R. Denver, Krystalynne Morris, Michael Lynch, Larissa L. Vassilieva, and W. Kelley Thomas
Science, 29 September 2000, p. 2342-2344
[Abstract] [Full Text]

Perspective: GENETICS:
L1 Retrotransposons Shape the Mammalian Genome

Haig H. Kazazian Jr.
Science, 18 August 2000, p. 1152-1153
[Summary] [Full Text]

Timing the Ancestor of the HIV-1 Pandemic Strains
B. Korber et al.
Science, 9 June 2000, p. 1789-1796
[Abstract] [Full Text]

Perspective: AIDS:
Origins of HIV

David M. Hillis
Science, 9 June 2000, p. 1757-1759
[Summary] [Full Text]

Evidence for the Evolution of Bdelloid Rotifers Without Sexual Reproduction or Genetic Exchange
David Mark Welch and Matthew Meselson
Science, 19 May 2000, p. 1211-1215
[Abstract] [Full Text]

Perspective: EVOLUTIONARY GENETICS:
Sinless Originals

Olivia P. Judson and Benjamin B. Normark
Science, 19 May 2000, p. 1185-1186
[Summary] [Full Text]

Review: Conservation and Novelty in the Evolution of Cell Adhesion and Extracellular Matrix Genes
Harald Hutter et al.
Science, 11 February 2000, p. 989-994
[Abstract] [Full Text]

Four Evolutionary Strata on the Human X Chromosome
Bruce T. Lahn and David C. Page
Science, 29 October 1999, p. 964-967
[Abstract] [Full Text]

News: EVOLUTIONARY GENETICS:
The Why Behind the Y Chromosome

Gretchen Vogel
Science, 29 October 1999, p. 877-879
[Summary] [Full Text]

Review: Chemical Etiology of Nucleic Acid Structure
Albert Eschenmoser
Science, 25 June 1999, p. 2118-2124
[Abstract] [Full Text]

Figure 1

Perspective: GENOMICS:
Mix and Match in the Tree of Life

James A. Lake, Ravi Jain, and Maria C. Rivera
Science, 26 March 1999, p. 2027-2028
[Summary] [Full Text]

Review: Mitochondrial Evolution
Michael W. Gray, Gertraud Burger, and B. Franz Lang
Science, 5 March 1999, p. 1476-1481
[Abstract] [Full Text]

A Rapidly Evolving Homeobox at the Site of a Hybrid Sterility Gene
Chau-Ti Ting, Shun-Chern Tsaur, Mao-Lien Wu, and Chung-I Wu
Science, 20 November 1998, pp. 1501-1504
[Abstract] [Full Text]

Perspectives: EVOLUTION:
Molecular Origin of Species

M. Nei and J. Zhang
Science, 20 November 1998, pp. 1428-1429
[Summary] [Full Text]

 




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