In its 11 April 2003 issue, Science presents a special collection of news, viewpoints, and other articles to celebrate the 50th anniversary of one of the signpost events of modern biology -- the publication of the structure of DNA -- and the new directions in molecular biology that the double-helix discovery has marked out in the subsequent half-century.

Special Section:
Building on the DNA Revolution

Introduction

Barbara R. Jasny and Leslie Roberts
Science 300, 277 (2003)

News

A Hothouse of Molecular Biology

Elizabeth Pennisi
Science 300, 278 (2003)

DNA's Cast of Thousands

Elizabeth Pennisi
Science 300, 282 (2003)

Viewpoints

The Human Genome Project: Lessons from Large-Scale Biology

Francis S. Collins, Michael Morgan, Aristides Patrinos
Science 300, 286 (2003)

Realizing the Potential of the Genome Revolution: The Genomes to Life Program

Marvin E. Frazier, Gary M. Johnson, David G. Thomassen, Carl E. Oliver, Aristides Patrinos
Science 300, 290 (2003)

From Knowing to Controlling: A Path from Genomics to Drugs Using Small Molecule Probes

Robert L. Strausberg and Stuart L. Schreiber
Science 300, 294 (2003)

Developing a Platform for Genomic Medicine in Mexico

Gerardo Jimenez-Sanchez
Science 300, 295 (2003)

Also of Genetic/Genomic Interest

Editorial

DNA: One Teacher's Reflection

Donald Kennedy
Science 300, 213 (2003)

Essay

Perceptions of Science: The Making of an Icon

Soraya de Chadarevian
Science 300, 255 (2003)

News Focus

Recruiting Genes, Proteins for a Revolution in Diagnostics

Robert F. Service
Science 300, 236 (2003)

Putting Gene Arrays to the Test

Malorye Branca
Science 300, 238 (2003)

Perspective

Defining Genes in the Genomics Era

Michael Snyder and Mark Gerstein
Science 300, 258 (2003)