Epitranscriptomics refers to changes in an organism’s cells resulting from posttranscriptional modification of cellular RNA. RNA-binding proteins (RBPs) play a crucial role in these posttranscriptional modifications and also support several cellular processes necessary for maintaining RNA homeostasis. Uncovering the mechanisms underlying RNA modifications and RBP function are emerging frontiers in medicine that take the study of gene regulation a step beyond epigenetics. Recent research has identified over 100 distinct posttranscriptional RNA modifications. These modifications are hypothesized to have roles beyond simply fine-tuning the structure and function of RNA, and studies have linked them to various disease syndromes. Similarly, perturbations in the function of RBPs may disrupt RNA processing, thereby implicating them in the pathogenesis of several disease states.
During the webinar, viewers will:
- Gain an understanding of the scope and mechanism of RNA modifications and RBP functions
- Learn more about how RNA modifications and RBPs may be involved in the development of disease states
- Hear about different approaches used to uncover mechanisms underlying RNA modifications and RBP function
- Have an opportunity to put their questions to the panel during the live broadcast.
This webinar will last for approximately 60 minutes.