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Advancing neuroimmunology: Untangling biomarkers in the brain

This webinar is brought to you by the Science/AAAS Custom Publishing Office

Advancing neuroimmunology: Untangling biomarkers in the brain

Recorded 28 October 2015

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Unraveling how the immune and nervous systems interact has helped advance our understanding of many mechanisms within the brain, from development to diseases. Inflammation and immune responses in the nervous system have been linked to a variety of brain disorders, including neurodegeneration, traumatic brain injury, stroke, and cognitive decline. Our knowledge of immune-related pathologies in the brain and the ability to identify biomarkers for disease and inflammation are key for forming meaningful mechanistic conclusions. In this webinar, our expert panel will share their experience researching neuroinflammation and neurodegeneration-related biomarkers, and will discuss methodologies for tracking pathological changes and quantifying specific inflammatory mediators, such as T cells, cytokines, and antibodies. 

During this webinar, the speakers will discuss:

  • Best practices and the challenges of studying biomarkers in the brain
  • Techniques for measuring immune-related molecules
  • Protocols for analyzing human samples as well as rodent models
  • And answer your questions live during the webinar!

The webinar will last approximately 60 minutes. 

To learn more about products or technologies related to this webinar, go to:  www.emdmillipore.com/milliplex

Speaker bios

Kristian Doyle, Ph.D.

University of Arizona
Tucson, AZ

Dr. Doyle is an assistant professor in the Departments of Immunobiology and Neurology at the University of Arizona. He earned his Ph.D. from Oregon Health & Science University in 2007, developing novel therapeutics for stroke in the laboratory of Dr. Mary Stenzel-Poore. Dr. Doyle then trained as a postdoctoral scholar at Stanford University under the mentorship of Dr. Marion Buckwalter, researching the role of transforming growth factor (TGF)-beta signaling after stroke and developing a model of poststroke dementia. Dr. Doyle was awarded an American Federation for Aging Research Fellowship in 2009, an Anita Roberts Young Scientist Scholarship in 2010, and a K99/R00 Pathway to Independence Award from the National Institute of Nursing Research in 2012. 

Thuy-Vi Nguyen, Ph.D.

University of Arizona
Tucson, AZ

Dr. Nguyen is a research assistant professor in the Department of Neurology and a research scientist in the Department of Immunobiology at the University of Arizona. She earned a Ph.D. from the University of Southern California in which she characterized the mechanisms of sex hormone-induced neuroprotection against apoptosis associated with Alzheimer's disease (AD). Dr. Nguyen then worked at the Buck Institute for Research on Aging and at Stanford University, where she investigated the signaling pathways underlying neurodegeneration and how the modulation of these pathways can influence the AD phenotype. Her research at Stanford University has contributed to the development of a small molecule peptide that is currently in Phase IIA clinical trials for AD. As part of the team studying poststroke dementia in Dr. Kristian Doyle's laboratory, Dr. Nguyen applies more than 10 years of experience in quantifying neurodegeneration, immune responses, and behavior in rodent models.

Tianna Hicklin, Ph.D.

Science/AAAS
Washington, DC

Dr. Hicklin studied biology at Colorado State University for her undergraduate education before earning a Ph.D. in neuroscience from the University of Colorado Anschutz Medical Campus. Prior to joining Science/AAAS, she worked as a science writer intern for the University of Colorado’s Office of Media and Public Relations in Denver, Colorado and for Brookhaven National Laboratory’s Media and Communications Office in Upton, New York. Dr. Hicklin is currently the assistant editor for the Science/AAAS Custom Publishing Office.

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