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CovCheck is a ready-to-use tool that confirms whole-genome amplification (WGA) coverage for next-generation sequencing (NGS) downstream workflows, providing users with a valuable method for determining the quality and integrity of amplified DNA. It gives them an accurate view of the genomic coverage of amplified DNA prior to engaging in additional costly and time-consuming NGS downstream processes, such as library preparation and DNA sequencing. CovCheck is an endpoint PCR–based kit in a convenient 96-well plate format. It is able to assess all human chromosomes in a single experiment and includes 24 different sets of primer pairs, each targeting a specific human chromosome and enabling evaluation of the genomic coverage of four independent, single-cell WGA experiments simultaneously.

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