DNA Copy Number Variation Array
Oxford Gene Technology
The range of research-validated CytoSure Molecular Arrays has been expanded to investigate DNA copy number variation (CNV) underlying a variety of genetic disorders. The arrays are the ideal complement to DNA sequencing, providing a particularly powerful tool for investigating the variety of aberrations underlying genetic disorders. Comparative genomic hybridization arrays (aCGH) are the gold standard for CNV detection and the 60-mer oligonucleotide probes utilized by OGT's aCGH platform have been shown to deliver superior CNV detection than alternative platforms. The expanded CytoSure Molecular Array portfolio now enables detection of CNV in genes associated with over 20 genetic disorders, including cardiovascular, inherited eye, intellectual disability, and neuromuscular disorders, as well as a range of inherited cancers. In addition, genes covering each disorder can be combined to create bespoke custom arrays, or further customized by the addition of novel content to suit each individual research project. All CytoSure Molecular Arrays are supplied with OGT's class-leading CytoSure Interpret Software.