The Macaque Genome

A Barrel of Monkey Genes

Laura M. Zahn, Barbara R. Jasny, Elizabeth Culotta, and Elizabeth Pennisi
Science 13 April 2007: 215.
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News

Boom Time for Monkey Research

Elizabeth Pennisi
Science 13 April 2007: 216-218.
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Genomicists Tackle the Primate Tree

Elizabeth Pennisi
Science 13 April 2007: 218-221.
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Perspective

Poster: The Macaque Genome

Science 13 April 2007: 246.
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Research Article

Evolutionary and Biomedical Insights from the Rhesus Macaque Genome

Rhesus Macaque Genome Sequencing and Analysis Consortium, Richard A. Gibbs, Jeffrey Rogers, Michael G. Katze, Roger Bumgarner, George M. Weinstock, Elaine R. Mardis, Karin A. Remington, Robert L. Strausberg, J. Craig Venter, Richard K. Wilson, Mark A. Batzer, Carlos D. Bustamante, Evan E. Eichler, Matthew W. Hahn, Ross C. Hardison, Kateryna D. Makova, Webb Miller, Aleksandar Milosavljevic, Robert E. Palermo, Adam Siepel, James M. Sikela, Tony Attaway, Stephanie Bell, Kelly E. Bernard, Christian J. Buhay, Mimi N. Chandrabose, Marvin Dao, Clay Davis, Kimberly D. Delehaunty, Yan Ding, Huyen H. Dinh, Shannon Dugan-Rocha, Lucinda A. Fulton, Ramatu Ayiesha Gabisi, Toni T. Garner, Jennifer Godfrey, Alicia C. Hawes, Judith Hernandez, Sandra Hines, Michael Holder, Jennifer Hume, Shalini N. Jhangiani, Vandita Joshi, Ziad Mohid Khan, Ewen F. Kirkness, Andrew Cree, R. Gerald Fowler, Sandra Lee, Lora R. Lewis, Zhangwan Li, Yih-shin Liu, Stephanie M. Moore, Donna Muzny, Lynne V. Nazareth, Dinh Ngoc Ngo, Geoffrey O. Okwuonu, Grace Pai, David Parker, Heidie A. Paul, Cynthia Pfannkoch, Craig S. Pohl, Yu-Hui Rogers, San Juana Ruiz, Aniko Sabo, Jireh Santibanez, Brian W. Schneider, Scott M. Smith, Erica Sodergren, Amanda F. Svatek, Teresa R. Utterback, Selina Vattathil, Wesley Warren, Courtney Sherell White, Asif T. Chinwalla, Yucheng Feng, Aaron L. Halpern, LaDeana W. Hillier, Xiaoqiu Huang, Pat Minx, Joanne O. Nelson, Kymberlie H. Pepin, Xiang Qin, Granger G. Sutton, Eli Venter, Brian P. Walenz, John W. Wallis, Kim C. Worley, Shiaw-Pyng Yang, Steven M. Jones, Marco A. Marra, Mariano Rocchi, Jacqueline E. Schein, Robert Baertsch, Laura Clarke, Miklós Csürös, Jarret Glasscock, R. Alan Harris, Paul Havlak, Andrew R. Jackson, Huaiyang Jiang, Yue Liu, David N. Messina, Yufeng Shen, Henry Xing-Zhi Song, Todd Wylie, Lan Zhang, Ewan Birney, Kyudong Han, Miriam K. Konkel, Jungnam Lee, Arian F. A. Smit, Brygg Ullmer, Hui Wang, Jinchuan Xing, Richard Burhans, Ze Cheng, John E. Karro, Jian Ma, Brian Raney, Xinwei She, Michael J. Cox, Jeffery P. Demuth, Laura J. Dumas, Sang-Gook Han, Janet Hopkins, Anis Karimpour-Fard, Young H. Kim, Jonathan R. Pollack, Tomas Vinar, Charles Addo-Quaye, Jeremiah Degenhardt, Alexandra Denby, Melissa J. Hubisz, Amit Indap, Carolin Kosiol, Bruce T. Lahn, Heather A. Lawson, Alison Marklein, Rasmus Nielsen, Eric J. Vallender, Andrew G. Clark, Betsy Ferguson, Ryan D. Hernandez, Kashif Hirani, Hildegard Kehrer-Sawatzki, Jessica Kolb, Shobha Patil, Ling-Ling Pu, Yanru Ren, David Glenn Smith, David A. Wheeler, Ian Schenck, Edward V. Ball, Rui Chen, David N. Cooper, Belinda Giardine, Fan Hsu, W. James Kent, Arthur Lesk, David L. Nelson, William E. O'Brien, Kay Prüfer, Peter D. Stenson, James C. Wallace, Hui Ke, Xiao-Ming Liu, Peng Wang, Andy Peng Xiang, Fan Yang, Galt P. Barber, David Haussler, Donna Karolchik, Andy D. Kern, Robert M. Kuhn, Kayla E. Smith, and Ann S. Zwieg
Science 13 April 2007: 222-234.
Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Reports

Human-Specific Changes of Genome Structure Detected by Genomic Triangulation

R. A. Harris, J. Rogers, and A. Milosavljevic
Science 13 April 2007: 235-237.
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Mobile DNA in Old World Monkeys: A Glimpse Through the Rhesus Macaque Genome

Kyudong Han, Miriam K. Konkel, Jinchuan Xing, Hui Wang, Jungnam Lee, Thomas J. Meyer, Charles T. Huang, Erin Sandifer, Kristi Hebert, Erin W. Barnes, Robert Hubley, Webb Miller, Arian F. A. Smit, Brygg Ullmer, and Mark A. Batzer
Science 13 April 2007: 238-240.
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Demographic Histories and Patterns of Linkage Disequilibrium in Chinese and Indian Rhesus Macaques

Ryan D. Hernandez, Melissa J. Hubisz, David A. Wheeler, David G. Smith, Betsy Ferguson, Jeffrey Rogers, Lynne Nazareth, Amit Indap, Traci Bourquin, John McPherson, Donna Muzny, Richard Gibbs, Rasmus Nielsen, and Carlos D. Bustamante
Science 13 April 2007: 240-243.
Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Evolutionary Formation of New Centromeres in Macaque

Mario Ventura, Francesca Antonacci, Maria Francesca Cardone, Roscoe Stanyon, Pietro D'Addabbo, Angelo Cellamare, L. James Sprague, Evan E. Eichler, Nicoletta Archidiacono, and Mariano Rocchi
Science 13 April 2007: 243-246.
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This Week in Science

Editor summaries of this week's papers.
Science 13 April 2007: 169.
|Full Text »

Editorial:
Moving the Primate Debate Forward

David Weatherall and Helen Munn
Science 13 April 2007: 173.
Summary »|   Full Text »|   PDF »|  

Editors' Choice

Highlights of the recent literature.
Science 13 April 2007: 174.
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Quarterly Author Index

Science 13 April 2007: 299.
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NEW PRODUCTS

Science 13 April 2007: 299.
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News of the Week

INTELLECTUAL PROPERTY: U.S. Patent Office Casts Doubt on Wisconsin Stem Cell Patents

Constance Holden
Science 13 April 2007: 182.
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NORTH KOREA: A Mission to Educate the Elite

Richard Stone
Science 13 April 2007: 183.
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U.S. IMMIGRATION POLICY: Study Finds Foreign High-Tech Workers Earn Less

Yudhijit Bhattacharjee
Science 13 April 2007: 184.
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U.S. ACADEMIC RESEARCH: NSF to Revisit Cost-Sharing Policies

Jeffrey Mervis
Science 13 April 2007: 184.
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GENETICS: Mysterious, Widespread Obesity Gene Found Through Diabetes Study

Jocelyn Kaiser
Science 13 April 2007: 185.
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SCIENCE POLICY: Japan Picks Up the 'Innovation' Mantra

Dennis Normile
Science 13 April 2007: 186.
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MATERIALS SCIENCE: Chemists Mold Metal Objects From Plastic 'Nanoputty'

Robert F. Service
Science 13 April 2007: 187.
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ScienceScope

Science 13 April 2007: 185.
|Full Text »

Random Samples

Science 13 April 2007: 179.
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Newsmakers

Science 13 April 2007: 181.
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News Focus

CLIMATE CHANGE: Global Warming Is Changing the World

Richard A. Kerr
Science 13 April 2007: 188-190.
Summary »|   Full Text »|   PDF »|  

IMMUNOLOGY: The Education of T Cells

Dan Ferber
Science 13 April 2007: 191-193.
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ASTRONOMY: Surveys of Exploding Stars Show One Size Does Not Fit All

Tom Siegfried
Science 13 April 2007: 194-195.
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AGRICULTURE: The Plant Breeder and the Pea

Erik Stokstad
Science 13 April 2007: 196-197.
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Letters

This Week's Letters

Science 13 April 2007: 198.
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 NIH Funding: What Does the Future Look Like?

Leo T. Furcht;, Milton H. Werner;, Maria Laura Avantaggiati;, and Elias A. Zerhouni
Science 13 April 2007: 198-200.
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 Are There Too Many Scientists?

Richard A. Collins
Science 13 April 2007: 200.
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 Fishing for Good News

Douglas J. McCauley;, John Sibert, John Hampton, Pierre Kleiber, and Mark Maunder
Science 13 April 2007: 200-201.
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 Corrections and Clarifications

Science 13 April 2007: 201.
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Books et al.

ENVIRONMENT: How Best to Look Forward?

M. Bruce Beck
Science 13 April 2007: 202-203.
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DANCE: From the Big Bang to the Mind

John Bohannon
Science 13 April 2007: 203.
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Books Received

Science 13 April 2007: 203.
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Policy Forum

ENVIRONMENT: Environmental Monitoring Network for India

P. V. Sundareshwar, R. Murtugudde, G. Srinivasan, S. Singh, K. J. Ramesh, R. Ramesh, S. B. Verma, D. Agarwal, D. Baldocchi, C. K. Baru, K. K. Baruah, G. R. Chowdhury, V. K. Dadhwal, C. B. S. Dutt, J. Fuentes, Prabhat K. Gupta, W. W. Hargrove, M. Howard, C. S. Jha, S. Lal, W. K. Michener, A. P. Mitra, J. T. Morris, R. R. Myneni, M. Naja, R. Nemani, R. Purvaja, S. Raha, S. K. Santhana Vanan, M. Sharma, A. Subramaniam, R. Sukumar, R. R. Twilley, and P. R. Zimmerman
Science 13 April 2007: 204-205.
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Perspectives

MEDICINE: LIGHT Hits the Liver

Goran K. Hansson
Science 13 April 2007: 206-207.
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CHEMISTRY: Femtosecond Lasers for Molecular Measurements

Robert P. Lucht
Science 13 April 2007: 207-208.
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IMMUNOLOGY: The Sources of a Lipid Conundrum

Jerold Chun
Science 13 April 2007: 208-210.
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CHEMISTRY: Putting Order into Polymer Networks

Peter M. Budd
Science 13 April 2007: 210-211.
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PLANETARY SCIENCE: As Tiny Worlds Turn

David P. Rubincam and Stephen J. Paddack
Science 13 April 2007: 211-212.
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ECOLOGY: A Positive Feedback with Negative Consequences

Manuel Lerdau
Science 13 April 2007: 212-213.
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RETROSPECTIVE: Frank Albert Cotton (1930-2007)

Tobin J. Marks
Science 13 April 2007: 214.
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Brevia

A Symmetric Bipolar Nebula Around MWC 922

P. G. Tuthill and J. P. Lloyd
Science 13 April 2007: 247.
The rectangular appearance of a stellar nebula may form because its polar winds, which are mirror images, are illuminated by young stars in still surroundings. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Research Articles

Quantum Structure of the Intermolecular Proton Bond

J. R. Roscioli, L. R. McCunn, and M. A. Johnson
Science 13 April 2007: 249-254.
Cold argon clusters and infrared spectroscopy reveal how the vibrations of two bases, such as ammonia and water, influence the behavior of a proton bound between them. Abstract »|   Full Text »|   PDF »|  

Structure of Fungal Fatty Acid Synthase and Implications for Iterative Substrate Shuttling

Simon Jenni, Marc Leibundgut, Daniel Boehringer, Christian Frick, Bohdan Mikolásek, and Nenad Ban
Science 13 April 2007: 254-261.
Fatty acid synthase comprises a biosynthetic pathway in which two-carbon units are sequentially added to tethered fatty acid chains by reactions at each of four catalytic sites. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Reports

Plastic and Moldable Metals by Self-Assembly of Sticky Nanoparticle Aggregates

Rafal Klajn, Kyle J. M. Bishop, Marcin Fialkowski, Maciej Paszewski, Christopher J. Campbell, Timothy P. Gray, and Bartosz A. Grzybowski
Science 13 April 2007: 261-264.
In a process similar to forming ceramics, metal nanoparticles coated with dithiol ligands can be shaped into objects and thermally annealed to create a porous, hardened material. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Optimizing the Laser-Pulse Configuration for Coherent Raman Spectroscopy

Dmitry Pestov, Robert K. Murawski, Gombojav O. Ariunbold, Xi Wang, Miaochan Zhi, Alexei V. Sokolov, Vladimir A. Sautenkov, Yuri V. Rostovtsev, Arthur Dogariu, Yu Huang, and Marlan O. Scully
Science 13 April 2007: 265-268.
Fluctuating background contributions to Raman spectra are minimized with shaped probe pulses, allowing detection and analysis of samples such as bacterial spores. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Designed Synthesis of 3D Covalent Organic Frameworks

Hani M. El-Kaderi, Joseph R. Hunt, José L. Mendoza-Cortés, Adrien P. Côté, Robert E. Taylor, Michael O'Keeffe, and Omar M. Yaghi
Science 13 April 2007: 268-272.
Organic molecular building blocks can be condensed into covalently bound crystalline solids with low density and high porosity, surface area, and thermal stability. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Direct Detection of the Asteroidal YORP Effect

Stephen C. Lowry, Alan Fitzsimmons, Petr Pravec, David Vokrouhlicky, Hermann Boehnhardt, Patrick A. Taylor, Jean-Luc Margot, Adrian Galád, Mike Irwin, Jonathan Irwin, and Peter Kusnirák
Science 13 April 2007: 272-274.
Published online 8 March 2007 [DOI: 10.1126/science.1139040] (in Science Express Reports)
Optical and radar observations of a near-Earth asteroid show that the radiation pressure from impacting sunlight is slowing its rotation, as predicted. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Spin Rate of Asteroid (54509) 2000 PH5 Increasing Due to the YORP Effect

Patrick A. Taylor, Jean-Luc Margot, David Vokrouhlicky, Daniel J. Scheeres, Petr Pravec, Stephen C. Lowry, Alan Fitzsimmons, Michael C. Nolan, Steven J. Ostro, Lance A. M. Benner, Jon D. Giorgini, and Christopher Magri
Science 13 April 2007: 274-277.
Published online 8 March 2007 [DOI: 10.1126/science.1139038] (in Science Express Reports)
Slowing of near-Earth asteroid (54509) 2000 PH5 is as expected for solar thermal torques as predicted by the YORP effect. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Analyses of Soft Tissue from Tyrannosaurus rex Suggest the Presence of Protein

Mary Higby Schweitzer, Zhiyong Suo, Recep Avci, John M. Asara, Mark A. Allen, Fernando Teran Arce, and John R. Horner
Science 13 April 2007: 277-280.
Mass spectroscopy reveals the protein sequence of collagen preserved in a Tyrannosaurus rex fossil, demonstrating that biochemical data can be obtained from long-extinct species. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Protein Sequences from Mastodon and Tyrannosaurus Rex Revealed by Mass Spectrometry

John M. Asara, Mary H. Schweitzer, Lisa M. Freimark, Matthew Phillips, and Lewis C. Cantley
Science 13 April 2007: 280-285.
Mass spectroscopy reveals the protein sequence of collagen preserved in a Tyrannosaurus rex fossil, demonstrating that biochemical data can be obtained from long-extinct species. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Lymphotoxin ß Receptor–Dependent Control of Lipid Homeostasis

James C. Lo, Yugang Wang, Alexei V. Tumanov, Michelle Bamji, Zemin Yao, Catherine A. Reardon, Godfrey S. Getz, and Yang-Xin Fu
Science 13 April 2007: 285-288.
Lipid levels in the blood, which are deregulated in atherosclerosis, are in part controlled by immune cells in the liver, suggesting a therapeutic target. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Structural Basis for Substrate Delivery by Acyl Carrier Protein in the Yeast Fatty Acid Synthase

Marc Leibundgut, Simon Jenni, Christian Frick, and Nenad Ban
Science 13 April 2007: 288-290.
Two flexible linkers allow a carrier protein to bounce from one catalytic site to the next as fatty acids are synthesized. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Structural Insight into Pre-B Cell Receptor Function

Alexander J. Bankovich, Stefan Raunser, Z. Sean Juo, Thomas Walz, Mark M. Davis, and K. Christopher Garcia
Science 13 April 2007: 291-294.
The structure of receptors on developing immune cells may explain how the cells acquire specificity for certain antigens and indicate that signaling occurs by oligomerization. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Promotion of Lymphocyte Egress into Blood and Lymph by Distinct Sources of Sphingosine-1-Phosphate

Rajita Pappu, Susan R. Schwab, Ivo Cornelissen, João P. Pereira, Jean B. Regard, Ying Xu, Eric Camerer, Yao-Wu Zheng, Yong Huang, Jason G. Cyster, and Shaun R. Coughlin
Science 13 April 2007: 295-298.
Published online 15 March 2007 [DOI: 10.1126/science.1139221] (in Science Express Reports)
Immune cells move into the bloodstream in response to a lipid signal made in red blood cells and move into the lymphatic system when the same signal is made elsewhere. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Technical Comments

Comment on "Wetland Sedimentation from Hurricanes Katrina and Rita"

Torbjörn E. Törnqvist, Chris Paola, Gary Parker, Kam-biu Liu, David Mohrig, John M. Holbrook, and Robert R. Twilley
Science 13 April 2007: 201.
Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Response to Comment on "Wetland Sedimentation from Hurricanes Katrina and Rita"

R. Eugene Turner, Joseph J. Baustian, Erick M. Swenson, and Jennifer S. Spicer
Science 13 April 2007: 201.
Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|