Detection Technologies

Chemical Detectives

Nancy Gough, Phil Szuromi, and Jake Yeston
Science 17 March 2006: 1565.
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Reviews

Ambient Mass Spectrometry

R. Graham Cooks, Zheng Ouyang, Zoltan Takats, and Justin M. Wiseman
Science 17 March 2006: 1566-1570.
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Probing Cellular Chemistry in Biological Systems with Microelectrodes

R. Mark Wightman
Science 17 March 2006: 1570-1574.
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This Week in Science

Editor summaries of this week's papers.
Science 17 March 2006: 1517.
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Editorial:
Fighting Tropical Diseases

Jeffrey D. Sachs and Peter J. Hotez
Science 17 March 2006: 1521.
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Editors' Choice

Highlights of the recent literature.
Science 17 March 2006: 1523.
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NetWatch

Best of the Web in science.
Science 17 March 2006: 1529.
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NEW PRODUCTS

Science 17 March 2006: 1625.
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News of the Week

NUCLEAR PHYSICS: Researchers Raise New Doubts About 'Bubble Fusion' Reports

Robert F. Service
Science 17 March 2006: 1532-1533.
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CHEMISTRY: Columbia Lab Retracts Key Catalysis Papers

Robert F. Service
Science 17 March 2006: 1533.
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COSMOLOGY: Magnet Experiment Appears to Drain Life From Stars

Michael Schirber
Science 17 March 2006: 1535.
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PLANETARY SCIENCE: Minerals Point to a Hot Origin for Icy Comets

Richard A. Kerr
Science 17 March 2006: 1536.
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U.S. REGULATORY POLICY: Courts Ruled No Forum for Data-Quality Fights

Jocelyn Kaiser
Science 17 March 2006: 1536.
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U.S. DEPARTMENT OF ENERGY: Can Energy Research Learn to Dance to a Livelier Tune?

Eli Kintisch
Science 17 March 2006: 1537.
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RUSSIAN SCIENCE: Moscow Plans Tighter Control of Science Academy's Research Money

Andrey Allakhverdov and Vladimir Pokrovsky
Science 17 March 2006: 1538.
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PARTICLE PHYSICS: Linear Collider Partners Woo Newly Opened India

Pallava Bagla
Science 17 March 2006: 1538.
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INFECTIOUS DISEASES: Report Concludes Polio Drugs Are Needed--After Disease Is Eradicated

Jennifer Couzin
Science 17 March 2006: 1539.
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SCIENTIFIC COMMUNITY: Bias Claim Stirs Up Ghost of Dolly

Gretchen Vogel and Eliot Marshall
Science 17 March 2006: 1539.
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ScienceScope

Science 17 March 2006: 1535.
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Random Samples

Science 17 March 2006: 1531.
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Newsmakers

Science 17 March 2006: 1551.
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News Focus

SPACE SCIENCE: A Space Race to the Bottom Line

Andrew Lawler
Science 17 March 2006: 1540-1543.
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SPACE SCIENCE: Bumpy Ride for Data-Driven NASA Chief

Andrew Lawler
Science 17 March 2006: 1542-1543.
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GENE SEQUENCING: The Race for the $1000 Genome

Robert F. Service
Science 17 March 2006: 1544-1546.
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PATIENT PRIVACY: Rule to Protect Records May Doom Long-Term Heart Study

Jocelyn Kaiser
Science 17 March 2006: 1547-1548.
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RESEARCH FUNDING: China Bets Big on Big Science

Hao Xin and Gong Yidong
Science 17 March 2006: 1548-1549.
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Letters

This Week's Letters

Science 17 March 2006: 1552.
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 Vaccine Against Spanish Flu

Jens C. Jensenius;, Terrence M. Tumpey, Christopher F. Basler, Patricia V. Aguilar, Hui Zeng, Alicia Solorzano, David E. Swayne, Nancy J. Cox, Jacqueline M. Katz, Jeffery K. Taubenberger, Peter Palese, and Adolfo Garcia-Sastre
Science 17 March 2006: 1552.
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 Williams-Beuren Syndrome

James J. Menegazzi
Science 17 March 2006: 1552.
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 Smaller, Hungrier Mice

Giovambattista Pani, Salvatore Fusco, Tommaso Galeotti;, Danica Chen, Andrew Steele, Susan Lindquist, and Leonard Guarente
Science 17 March 2006: 1553-1554.
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 Sea Urchins as Crystallographers

Kenneth M. Towe;, Stephen Weiner, and Lia Addadi
Science 17 March 2006: 1554-1555.
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Books et al.

APPLIED PHYSICS: Dr. Strangelove Moves Mountains

Hugh Gusterson
Science 17 March 2006: 1556.
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Books Received

Science 17 March 2006: 1556.
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Policy Forum

ECOLOGY: Globalization, Roving Bandits, and Marine Resources

F. Berkes, T. P. Hughes, R. S. Steneck, J. A. Wilson, D. R. Bellwood, B. Crona, C. Folke, L. H. Gunderson, H. M. Leslie, J. Norberg, M. Nyström, P. Olsson, H. Österblom, M. Scheffer, and B. Worm
Science 17 March 2006: 1557-1558.
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Perspectives

MATERIALS SCIENCE: Artificial Muscle Begins to Breathe

John D. Madden
Science 17 March 2006: 1559-1560.
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NEUROSCIENCE: Enhanced: Neuron, Know Thy Neighbor

Emanuel DiCicco-Bloom
Science 17 March 2006: 1560-1562.
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VIROLOGY: Clues to the Virulence of H5N1 Viruses in Humans

Robert M. Krug
Science 17 March 2006: 1562-1563.
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CHEMISTRY: Seamless Proteins Tie Up Their Loose Ends

David J. Craik
Science 17 March 2006: 1563-1564.
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Brevia

Seed Dispersal by Weta

Catherine Duthie, George Gibbs, and K. C. Burns
Science 17 March 2006: 1575.
Weta, giant flightless grasshoppers native to New Zealand, ingest and disperse seeds—-an ecological role played by small mammals in other parts of the world. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Research Article

Large-Scale Sequence Analysis of Avian Influenza Isolates

John C. Obenauer, Jackie Denson, Perdeep K. Mehta, Xiaoping Su, Suraj Mukatira, David B. Finkelstein, Xiequn Xu, Jinhua Wang, Jing Ma, Yiping Fan, Karen M. Rakestraw, Robert G. Webster, Erich Hoffmann, Scott Krauss, Jie Zheng, Ziwei Zhang, and Clayton W. Naeve
Science 17 March 2006: 1576-1580.
Published online 26 January 2006 [DOI: 10.1126/science.1121586] (in Science Express Research Articles)
Sequences from 169 isolates of avian influenza viruses, including many different strains, reveal that all have a motif located in a nonstructural gene that is necessary for virulence. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Reports

Fuel-Powered Artificial Muscles

Von Howard Ebron, Zhiwei Yang, Daniel J. Seyer, Mikhail E. Kozlov, Jiyoung Oh, Hui Xie, Joselito Razal, Lee J. Hall, John P. Ferraris, Alan G. MacDiarmid, and Ray H. Baughman
Science 17 March 2006: 1580-1583.
Artificial muscles made with carbon nanotubes or a shape memory alloy can be designed to act as fuel cells, thus alleviating a need for a remote battery power source. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Microstructured Optical Fibers as High-Pressure Microfluidic Reactors

Pier J. A. Sazio, Adrian Amezcua-Correa, Chris E. Finlayson, John R. Hayes, Thomas J. Scheidemantel, Neil F. Baril, Bryan R. Jackson, Dong-Jin Won, Feng Zhang, Elena R. Margine, Venkatraman Gopalan, Vincent H. Crespi, and John V. Badding
Science 17 March 2006: 1583-1586.
Semiconductors and metals can be deposited from high-pressure vapors inside optical fibers to form minute tubes, nanowires, and more complex patterned structures. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Saturn's Spokes: Lost and Found

C. J. Mitchell, M. Horányi, O. Havnes, and C. C. Porco
Science 17 March 2006: 1587-1589.
A model suggests that when Saturn’s rings are nearly edge-on to the Sun, lofted particles are able to remain positively charged and produce transient spokes in Saturn’s rings. Abstract »|   Full Text »|   PDF »|  

Visualizing Picometric Quantum Ripples of Ultrafast Wave-Packet Interference

Hiroyuki Katsuki, Hisashi Chiba, Bertrand Girard, Christoph Meier, and Kenji Ohmori
Science 17 March 2006: 1589-1592.
Two laser pulses, the first exciting vibrational modes and the second producing selective fluorescence, directly reveal the wavelike nature of a vibrating iodine molecule. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

MOSFET-Embedded Microcantilevers for Measuring Deflection in Biomolecular Sensors

Gajendra Shekhawat, Soo-Hyun Tark, and Vinayak P. Dravid
Science 17 March 2006: 1592-1595.
Published online 2 February 2006 [DOI: 10.1126/science.1122588] (in Science Express Reports)
The small bending created when biomolecules bind to receptors on a microfabricated cantilever can be detected with an embedded transistor, forming a microsensor. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Broadband Cavity Ringdown Spectroscopy for Sensitive and Rapid Molecular Detection

Michael J. Thorpe, Kevin D. Moll, R. Jason Jones, Benjamin Safdi, and Jun Ye
Science 17 March 2006: 1595-1599.
Coupling of a frequency comb with an optical cavity in which light is systematically absorbed produces a highly sensitive and accurate visible and near-infrared spectrometer. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Probing Gene Expression in Live Cells, One Protein Molecule at a Time

Ji Yu, Jie Xiao, Xiaojia Ren, Kaiqin Lao, and X. Sunney Xie
Science 17 March 2006: 1600-1603.
Visualization of individual proteins shows that translation of single messenger RNAs in E. coli yields random bursts of new protein molecules. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Late Colonization of Easter Island

Terry L. Hunt and Carl P. Lipo
Science 17 March 2006: 1603-1606.
Published online 9 March 2006 [DOI: 10.1126/science.1121879] (in Science Express Reports)
Radiocarbon dates imply that voyaging Polynesians arrived on Easter Island around 1200 A.D., later than previously thought, and soon began depleting timber and other natural resources and erecting statues. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Reward Timing in the Primary Visual Cortex

Marshall G. Shuler and Mark F. Bear
Science 17 March 2006: 1606-1609.
Neurons in the primary visual cortex respond differently to a flash of light after it has been paired with a re w a rd, unexpectedly showing that cognitive information is coded at this level in the cortex. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

E-Catenin Controls Cerebral Cortical Size by Regulating the Hedgehog Signaling Pathway

Wen-Hui Lien, Olga Klezovitch, Tania E. Fernandez, Jeff Delrow, and Valeri Vasioukhin
Science 17 March 2006: 1609-1612.
Specialized junctions between neurons during development help control the number of cells in the brain, and thus final brain size. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

State-Dependent Learned Valuation Drives Choice in an Invertebrate

Lorena Pompilio, Alex Kacelnik, and Spencer T. Behmer
Science 17 March 2006: 1613-1615.
Grasshoppers prefer foods that they previously encountered when very hungry, illustrating a sophisticated form of learning unexpected in an insect. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

An Equivalence Principle for the Incorporation of Favorable Mutations in Asexual Populations

Matthew Hegreness, Noam Shoresh, Daniel Hartl, and Roy Kishony
Science 17 March 2006: 1615-1617.
Evolution of asexual populations, as in bacteria, viruses, or cancer cells, is described by a model in which all beneficial mutations have equal effects and occur at the same rate. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Parietal-Eye Phototransduction Components and Their Potential Evolutionary Implications

Chih-Ying Su, Dong-Gen Luo, Akihisa Terakita, Yoshinori Shichida, Hsi-Wen Liao, Manija A. Kazmi, Thomas P. Sakmar, and King-Wai Yau
Science 17 March 2006: 1617-1621.
Lizards’ third eye, which senses only light intensity, uses both vertebrate- and invertebrate-like signaling molecules, suggesting an evolutionary path for vertebrate phototransduction. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

A Protein Farnesyltransferase Inhibitor Ameliorates Disease in a Mouse Model of Progeria

Loren G. Fong, David Frost, Margarita Meta, Xin Qiao, Shao H. Yang, Catherine Coffinier, and Stephen G. Young
Science 17 March 2006: 1621-1623.
Published online 16 February 2006 [DOI: 10.1126/science.1124875] (in Science Express Reports)
A drug that inhibits the addition of lipids to proteins has beneficial effects in a mouse version of a rare premature aging disorder, suggesting that it may be useful in children with the disease. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Technical Comments

Comment on "Ivory-billed Woodpecker (Campephilus principalis) Persists in Continental North America"

David A. Sibley, Louis R. Bevier, Michael A. Patten, and Chris S. Elphick
Science 17 March 2006: 1555.
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Response to Comment on "Ivory-billed Woodpecker (Campephilus principalis) Persists in Continental North America"

John W. Fitzpatrick, Martjan Lammertink, M. David Luneau, Jr., Tim W. Gallagher, and Kenneth V. Rosenberg
Science 17 March 2006: 1555.
Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|