COVER The integral membrane portion of the mammalian Shaker family potassium channel, Kv1.2, viewed from the extracellular solution. The channel is gradually colored from its amino terminus (red) to its carboxyl terminus (blue) and is illustrated with sticks. A green sphere represents a potassium ion in the central ion conduction pathway. See page 897. [Image: S. B. Long et al.]

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