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Science Signaling - Call for Papers

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About the Cover

Cover Figure


COVER A surface representation of human Toll-like receptor 3, derived from the x-ray crystal structure and shown on a cell membrane. The glycosylated Toll-like receptor dimer (green with pink sugars) recognizes double-stranded RNA (orange) from microbial pathogens such as viruses (lavender). Binding of the RNA to the receptor activates the innate immune system. The structure is described on page 581. [Image: J. Choe, M. Pique, and I. A. Wilson]

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Science. ISSN 0036-8075 (print), 1095-9203 (online)