Women's Health

Vive la Différence

Beverly Purnell, Leslie Roberts, and Orla Smith
Science 10 June 2005: 1569.
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News

From Dearth to Deluge

Eliot Marshall
Science 10 June 2005: 1570.
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Clinical Trials: Keeping Score on the Sexes

Eliot Marshall
Science 10 June 2005: 1571.
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Gender in the Pharmacy: Does It Matter?

Jocelyn Kaiser
Science 10 June 2005: 1572.
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Sex and the Suffering Brain

Constance Holden
Science 10 June 2005: 1574.
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Poor Countries, Added Perils for Women

Greg Miller
Science 10 June 2005: 1576.
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Let's Talk About Sex--and Drugs

Martin Enserink
Science 10 June 2005: 1578.
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Bone Quality Fills Holes in Fracture Risk

Erik Stokstad
Science 10 June 2005: 1580.
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Reviews

HIV/AIDS in Women: An Expanding Epidemic

Thomas C. Quinn and Julie Overbaugh
Science 10 June 2005: 1582-1583.
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Molecular and Cellular Basis of Cardiovascular Gender Differences

Michael E. Mendelsohn and Richard H. Karas
Science 10 June 2005: 1583-1587.
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The Pains of Endometriosis

Karen J. Berkley, Andrea J. Rapkin, and Raymond E. Papka
Science 10 June 2005: 1587-1589.
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Uterine Fibroids: The Elephant in the Room

Cheryl Lyn Walker and Elizabeth A. Stewart
Science 10 June 2005: 1589-1592.
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Latest Advances in Understanding Preeclampsia

Christopher W. Redman and Ian L. Sargent
Science 10 June 2005: 1592-1594.
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This Week in Science

Editor summaries of this week's papers.
Science 10 June 2005: 1513.
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Editorial:
Wanted: Women in Clinical Trials

Viviana Simon
Science 10 June 2005: 1517.
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Editors' Choice

Highlights of the recent literature.
Science 10 June 2005: 1519.
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NetWatch

Best of the Web in science.
Science 10 June 2005: 1525.
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 New Products

Science 17 June 2005: 1647.
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News of the Week

SCIENCE AND SOCIETY:
Smithsonian Gives Grudging OK to Film Backing ID Argument

Yudhijit Bhattacharjee
Science 10 June 2005: 1526.
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U.S. SCIENCE BUDGET:
VA Asked to Bolster Mental Health Research

Jennifer Couzin
Science 10 June 2005: 1526-1527.
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PSYCHOLOGY:
Survey Finds U.S. Mental Health Holds Steady

Constance Holden
Science 10 June 2005: 1527.
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PROTEOMICS:
Canadian Global Database May Move to Singapore After Loss of Funding

Wayne Kondro
Science 10 June 2005: 1529.
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CLIMATE CHANGE:
California Sets Goals for Cutting Greenhouse Gases

Erik Stokstad
Science 10 June 2005: 1530.
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EUROPEAN UNION:
Researchers Lobby to Head Off Threatened Cuts

Gretchen Vogel
Science 10 June 2005: 1530.
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MICROBIOLOGY:
Mosquito-Killing Fungi May Join the Battle Against Malaria

Martin Enserink
Science 10 June 2005: 1531-1533.
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GENETICS:
In Voles, a Little Extra DNA Makes for Faithful Mates

Elizabeth Pennisi
Science 10 June 2005: 1533.
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ScienceScope

Science 10 June 2005: 1529.
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Random Samples

Science 10 June 2005: 1545.
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News Focus

CELL BIOLOGY:
Ready or Not? Human ES Cells Head Toward the Clinic

Gretchen Vogel
Science 10 June 2005: 1534-1538.
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CELL BIOLOGY:
Still Waiting Their Turn

Gretchen Vogel
Science 10 June 2005: 1536-1537.
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CELL BIOLOGY:
Human Embryonic Stem Cells May Be Toxicology's New Best Friends

Gunjan Sinha
Science 10 June 2005: 1538.
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VIROLOGY:
Culture Systems for Hepatitis C Virus in Sight at Last

Jon Cohen
Science 10 June 2005: 1539-1541.
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PHYSIOLOGY:
Science in the 'Death Zone'

Fiona Proffitt
Science 10 June 2005: 1541-1542.
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HIGH-ENERGY PHYSICS:
KEK Researchers Catch Glimpse of Outlandish Particles

Charles Seife
Science 10 June 2005: 1543.
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Letters

This Week's Letters

Science 10 June 2005: 1549.
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 The Question of Forbidden Knowledge

Owen M. Williamson;, Michael C. Wendl;, Jefferson M. Fish;, Joanna Kempner, Clifford S. Perlis, and Jon F. Merz
Science 10 June 2005: 1549-1550.
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 The Problems of Radiocarbon Dating

Maarten Blaauw, J. Andrés Christen;, Tom P. Guilderson, Paula J. Reimer, and Tom A. Brown
Science 10 June 2005: 1551-1553.
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Books et al.

HUMAN GENETICS:
Lessons from the HGDP?

Henry T. Greely
Science 10 June 2005: 1554-1555.
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MEDICINE:
Addressing Pregnancy Loss

John Aplin
Science 10 June 2005: 1555.
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 Books Received

Science 10 June 2005: 1555.

Policy Forum

PUBLIC HEALTH:
Pharmacist Refusals: A Threat to Women's Health

Marcia D. Greenberger and Rachel Vogelstein
Science 10 June 2005: 1557-1558.
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PUBLIC HEALTH:
Conscientious Objection and the Pharmacist

Henri R. Manasse, Jr.
Science 10 June 2005: 1558-1559.
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Perspectives

BIOMEDICINE:
Asthmatics Breathe Easier When It's SNO-ing

Craig Gerard
Science 10 June 2005: 1560-1561.
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APPLIED PHYSICS:
Nanoantennas for Light Emission

Jean-Jacques Greffet
Science 10 June 2005: 1561-1563.
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IMMUNOLOGY:
Opposites Attract in Differentiating T Cells

Mark Bix, Sunhwa Kim, and Anjana Rao
Science 10 June 2005: 1563-1565.
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PSYCHOLOGY:
Appearance DOES Matter

Leslie A. Zebrowitz and Joann M. Montepare
Science 10 June 2005: 1565-1566.
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MATERIALS SCIENCE:
Enhanced: Snapshots of Crystal Growth

Michael D. Ward
Science 10 June 2005: 1566-1567.
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Brevia

Observations by the International Tsunami Survey Team in Sri Lanka

Philip L.-F. Liu, Patrick Lynett, Harindra Fernando, Bruce E. Jaffe, Hermann Fritz, Bretwood Higman, Robert Morton, James Goff, and Costas Synolakis
Science 10 June 2005: 1595.
Satellite observations and ground measurements document that the 26 December 2004 tsunami reached heights of 10 to 25 meters at Banda Aceh and 3 to 12.5 meters on Sri Lanka. Abstract »|   Full Text »|   PDF »|  

Field Data and Satellite Imagery of Tsunami Effects in Banda Aceh

Jose C. Borrero
Science 10 June 2005: 1596.
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Research Article

The Kinase Domain of Titin Controls Muscle Gene Expression and Protein Turnover

Stephan Lange, Fengqing Xiang, Andrey Yakovenko, Anna Vihola, Peter Hackman, Elena Rostkova, Jakob Kristensen, Birgit Brandmeier, Gereon Franzen, Birgitta Hedberg, Lars Gunnar Gunnarsson, Simon M. Hughes, Sylvie Marchand, Thomas Sejersen, Isabelle Richard, Lars Edström, Elisabeth Ehler, Bjarne Udd, and Mathias Gautel
Science 10 June 2005: 1599-1603.
Published online 31 March 2005 [DOI: 10.1126/science.1110463] (in Science Express Research Articles)
The giant muscle protein titin, through its kinase domain, communicates mechanical changes to the nucleus to remodel muscle characteristics through modulation of gene expression by other signaling molecules. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Reports

Infrared Echoes near the Supernova Remnant Cassiopeia A

Oliver Krause, George H. Rieke, Stephan M. Birkmann, Emeric Le Floc'h, Karl D. Gordon, Eiichi Egami, John Bieging, John P. Hughes, Erick T. Young, Joannah L. Hinz, Sascha P. Quanz, and Dean C. Hines
Science 10 June 2005: 1604-1606.
A supernova remnant seems to contain a highly magnetized neutron star that is heating nearby dust and generating infrared echoes that are moving at nearly the speed of light. Abstract »|   Full Text »|   PDF »|  

Resonant Optical Antennas

P. Mühlschlegel, H.-J. Eisler, O. J. F. Martin, B. Hecht, and D. W. Pohl
Science 10 June 2005: 1607-1609.
Split strips of gold, each with a width of about half the wavelength of light, can act as optical antennas, capturing incident light in the gold arms and focusing the energy into the small gap. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Giant Larvacean Houses: Rapid Carbon Transport to the Deep Sea Floor

Bruce H. Robison, Kim R. Reisenbichler, and Rob E. Sherlock
Science 10 June 2005: 1609-1611.
Surprisingly, the discarded feeding structures of giant larvaceans carry nearly as much carbon to the ocean's depths as does the rain of small particles. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Rapid Acidification of the Ocean During the Paleocene-Eocene Thermal Maximum

James C. Zachos, Ursula Röhl, Stephen A. Schellenberg, Appy Sluijs, David A. Hodell, Daniel C. Kelly, Ellen Thomas, Micah Nicolo, Isabella Raffi, Lucas J. Lourens, Heather McCarren, and Dick Kroon
Science 10 June 2005: 1611-1615.
A dramatic increase in the dissolution of calcium carbonate at the Paleocene-Eocene thermal maximum indicates that far more CO₂ was added to the oceans than had been thought. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Photoinduced Plasticity in Cross-Linked Polymers

Timothy F. Scott, Andrew D. Schneider, Wayne D. Cook, and Christopher N. Bowman
Science 10 June 2005: 1615-1617.
A cross-linked polymer network with added allyl sulfide groups can be reformed by exposure to ultraviolet light, allowing tunable control of its properties. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Protection from Experimental Asthma by an Endogenous Bronchodilator

Loretta G. Que, Limin Liu, Yun Yan, Gregory S. Whitehead, Stephen H. Gavett, David A. Schwartz, and Jonathan S. Stamler
Science 10 June 2005: 1618-1621.
Published online 26 May 2005 [DOI: 10.1126/science.1108228] (in Science Express Reports)
A nitric oxide-carrying molecule protects against hyperactivity of lung airways in a model of asthma. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Trophic Cascades in a Formerly Cod-Dominated Ecosystem

Kenneth T. Frank, Brian Petrie, Jae S. Choi, and William C. Leggett
Science 10 June 2005: 1621-1623.
Severe overfishing of cod, a top predator, in the northwest Atlantic has led to an increase in small fishes and invertebrates and has altered plankton dynamics and ocean chemistry. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Inferences of Competence from Faces Predict Election Outcomes

Alexander Todorov, Anesu N. Mandisodza, Amir Goren, and Crystal C. Hall
Science 10 June 2005: 1623-1626.
The perceived competence (maturity and attractiveness) in candidates' faces reliably predicts the chance of electoral success. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

TLR11 Activation of Dendritic Cells by a Protozoan Profilin-Like Protein

Felix Yarovinsky, Dekai Zhang, John F. Andersen, Gerard L. Bannenberg, Charles N. Serhan, Matthew S. Hayden, Sara Hieny, Fayyaz S. Sutterwala, Richard A. Flavell, Sankar Ghosh, and Alan Sher
Science 10 June 2005: 1626-1629.
Published online 28 April 2005 [DOI: 10.1126/science.1109893] (in Science Express Reports)
A protein from a protozoan parasite triggers a receptor of the innate immune system, a protective response similar to that seen for bacterial pathogens. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Microsatellite Instability Generates Diversity in Brain and Sociobehavioral Traits

Elizabeth A. D. Hammock and Larry J. Young
Science 10 June 2005: 1630-1634.
In prairie voles, the strength of mate bonding is controlled by the size of a repetitive DNA sequence in the regulatory region of the gene for a brain hormone receptor. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Diversity of the Human Intestinal Microbial Flora

Paul B. Eckburg, Elisabeth M. Bik, Charles N. Bernstein, Elizabeth Purdom, Les Dethlefsen, Michael Sargent, Steven R. Gill, Karen E. Nelson, and David A. Relman
Science 10 June 2005: 1635-1638.
Published online 14 April 2005 [DOI: 10.1126/science.1110591] (in Science Express Reports)
Genetic analysis of colon samples from healthy people reveals that different people harbor rather different microbe populations, some of which were previously undescribed. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Fungal Pathogen Reduces Potential for Malaria Transmission

Simon Blanford, Brian H. K. Chan, Nina Jenkins, Derek Sim, Ruth J. Turner, Andrew F. Read, and Matt B. Thomas
Science 10 June 2005: 1638-1641.
A fungus already used to control locusts eliminates more than 90% of malaria-infected mosquitoes in lab tests and inhibits development of the malaria parasite in the field. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

An Entomopathogenic Fungus for Control of Adult African Malaria Mosquitoes

Ernst-Jan Scholte, Kija Ng'habi, Japheth Kihonda, Willem Takken, Krijn Paaijmans, Salim Abdulla, Gerry F. Killeen, and Bart G. J. Knols
Science 10 June 2005: 1641-1642.
A fungus already used to control locusts eliminates more than 90% of malaria-infected mosquitoes in lab tests and inhibits development of the malaria parasite in the field. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Endosomal Proteolysis of the Ebola Virus Glycoprotein Is Necessary for Infection

Kartik Chandran, Nancy J. Sullivan, Ute Felbor, Sean P. Whelan, and James M. Cunningham
Science 10 June 2005: 1643-1645.
Published online 14 April 2005 [DOI: 10.1126/science.1110656] (in Science Express Reports)
For the Ebola virus to infect successfully, a host enzyme must digest a surface protein on the virus, suggesting a new target for treatment of this fatal infection. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Technical Comments

 Comment on "Thymic Origin of Intestinal ß T Cells Revealed by Fate Mapping of RORt⁺ Cells"

Benedita Rocha
Science 10 June 2005: 1553.
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 Response to Comment on "Thymic Origin of Intestinal ß T Cells Revealed by Fate Mapping of RORt⁺ Cells"

Gérard Eberl and Dan R Littman
Science 10 June 2005: 1553.
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