This Week in Science

Editor summaries of this week's papers.
Science 21 May 2004: 1073.
|Full Text »

Editorial:
Praise, for a Change

Donald Kennedy
Science 21 May 2004: 1077.
Summary »|   PDF »|  

Editors' Choice

Highlights of the recent literature.
Science 21 May 2004: 1079.
|Full Text »

NetWatch

Best of the Web in science.
Science 21 May 2004: 1087.
|Full Text »

 New Products

Science 21 May 2004: 1174.
PDF »|  

News of the Week

BIOTECHNOLOGY:
Monsanto Pulls the Plug on Genetically Modified Wheat

Erik Stokstad
Science 21 May 2004: 1088-1089.
Summary »|   Full Text »|   PDF »|  

STEM CELL RESEARCH:
Zerhouni's Answer Buoys Supporters

Constance Holden
Science 21 May 2004: 1088.
Summary »|   Full Text »|   PDF »|  

BIOTECHNOLOGY:
A New Tack on Herbicide Resistance

Erik Stokstad
Science 21 May 2004: 1089.
Summary »|   Full Text »|   PDF »|  

BIOMEDICAL ETHICS:
House Committee Slams NIH's Plan on Consulting

Jocelyn Kaiser
Science 21 May 2004: 1091.
Summary »|   Full Text »|   PDF »|  

EXOPLANETS:
Hotter-Than-Hot Newcomers Push the Planetary Envelope

Govert Schilling
Science 21 May 2004: 1092.
Summary »|   Full Text »|   PDF »|  

COSMOLOGY:
Galaxy Clusters Bear Witness to Universal Speed-Up

Adrian Cho
Science 21 May 2004: 1092.
Summary »|   Full Text »|   PDF »|  

GENETICS:
Genome Resources to Boost Canines' Role in Gene Hunts

Elizabeth Pennisi
Science 21 May 2004: 1093-1095.
Summary »|   Full Text »|   PDF »|  

NUMBER THEORY:
Proof Promises Progress in Prime Progressions

Barry Cipra
Science 21 May 2004: 1095.
Summary »|   Full Text »|   PDF »|  

DISEASE ERADICATION:
Two Steps Forward, One Step Back in Polio Fight

Leslie Roberts
Science 21 May 2004: 1096.
Summary »|   Full Text »|   PDF »|  

ARCHAEOLOGY:
Iranian Dig Opens Window on New Civilization

Andrew Lawler
Science 21 May 2004: 1096-1097.
Summary »|   Full Text »|   PDF »|  

INFECTIOUS DISEASES:
One Year After Outbreak, SARS Virus Yields Some Secrets

Martin Enserink
Science 21 May 2004: 1097.
Summary »|   Full Text »|   PDF »|  

ScienceScope

Science 21 May 2004: 1091.
|Full Text »

Random Samples

Science 21 May 2004: 1106.
|Full Text »

News Focus

EASTERN EUROPE:
Banishing Moldova's Demons

Richard Stone
Science 21 May 2004: 1098-1100.
Summary »|   Full Text »|   PDF »|  

EASTERN EUROPE:
Transdniestria: Scientists Left Isolated and Frustrated

Richard Stone
Science 21 May 2004: 1100.
Summary »|   Full Text »|   PDF »|  

PHYSICS:
Gran Sasso Laboratory Sees Light at the End of the Tunnel

Gretchen Vogel
Science 21 May 2004: 1101.
Summary »|   Full Text »|   PDF »|  

MIROSLAV RADMAN PROFILE:
Bringing Biology Back to Croatia

Peter Follette
Science 21 May 2004: 1103-1104.
Summary »|   Full Text »|   PDF »|  

MARINE SCIENCE:
New Tools Reveal Treasures at Ocean Hot Spots

David Malakoff
Science 21 May 2004: 1104-1105.
Summary »|   Full Text »|   PDF »|  

Letters

This Week's Letters

Science 21 May 2004: 1109.
Summary »|   PDF »|  

 Deforestation in Amazonia

William F. Laurance, Ana K. M. Albernaz, Philip M. Fearnside, Heraldo L. Vasconcelos, and Leandro V. Ferreira
Science 21 May 2004: 1109-1111.
Full Text »|   PDF »|  

 Painful Deception

Franklin G. Miller; and Tor Wager
Science 21 May 2004: 1109-1111.
Full Text »|   PDF »|  

 Wisdom in Self-Scrutiny

Rebecca Dresser
Science 21 May 2004: 1111.
Full Text »|   PDF »|  

 Bismuth Decays

H. Henry Stroke
Science 21 May 2004: 1111.
Full Text »|   PDF »|  

Books et al.

ANTHROPOLOGY:
Food for the Gods

Pamela Ronald
Science 21 May 2004: 1112-1113.
Summary »|   Full Text »|   PDF »|  

INVERTEBRATE ZOOLOGY:
An Ancient Lineage Worth Saving

Mark S. Garland
Science 21 May 2004: 1113.
Summary »|   Full Text »|   PDF »|  

 Books Received

Science 21 May 2004: 1113.

Policy Forum

SCIENCE AND INDUSTRY:
Oil: Never Cry Wolf--Why the Petroleum Age Is Far from over

Leonardo Maugeri
Science 21 May 2004: 1114-1115.
Summary »|   Full Text »|   PDF »|  

Perspectives

ASTRONOMY:
The Cradle of the Solar System

J. Jeff Hester, Steven J. Desch, Kevin R. Healy, and Laurie A. Leshin
Science 21 May 2004: 1116-1117.
Summary »|   Full Text »|   PDF »|  

EVOLUTION:
Insights into Innovation

Douglas H. Erwin and David C. Krakauer
Science 21 May 2004: 1117-1119.
Summary »|   Full Text »|   PDF »|  

CHEMISTRY:
Enhanced: The Structure of Protonated Water Clusters

Timothy S. Zwier
Science 21 May 2004: 1119-1120.
Published online 29 April 2004 [DOI: 10.1126/science.1098129] (in Science Express Perspectives)
Summary »|   Full Text »|   PDF »|  

BIOMEDICINE:
Parkinson's--Divergent Causes, Convergent Mechanisms

J. Timothy Greenamyre and Teresa G. Hastings
Science 21 May 2004: 1120-1122.
Summary »|   Full Text »|   PDF »|  

MICROBIOLOGY:
A Hitchhiker's Guide to Type IV Secretion

Suzanne R. Lybarger and Maria Sandkvist
Science 21 May 2004: 1122-1123.
Summary »|   Full Text »|   PDF »|  

CELL BIOLOGY:
Tickling Macrophages, a Serious Business

Stephanie Züllig and Michael O. Hengartner
Science 21 May 2004: 1123-1124.
Summary »|   Full Text »|   PDF »|  

Brevia

 Genetic Evidence for the Demic Diffusion of Agriculture to India

Richard Cordaux, Edwin Deepa, H. Vishwanathan, and Mark Stoneking
Science 21 May 2004: 1125.
Indian agricultural practices were spread by migration and interbreeding of farmers with hunter-gatherer societies, rather than by diffusion of technology. Full Text »|   PDF »|   Supporting Online Material »|  

Research Article

Coeval Large-Scale Magmatism in the Kalahari and Laurentian Cratons During Rodinia Assembly

Richard E. Hanson, James L. Crowley, Samuel A. Bowring, Jahandar Ramezani, Wulf A. Gose, Ian W. D. Dalziel, James A. Pancake, Emily K. Seidel, Thomas G. Blenkinsop, and Joshua Mukwakwami
Science 21 May 2004: 1126-1129.
Published online 22 April 2004 [DOI: 10.1126/science.1096329] (in Science Express Research Articles)
A huge region of magmatic activity spanned the ancient cores of South Africa and North America about 1108 million years ago when these continents became juxtaposed as part of a supercontinent. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Reports

Optical Signatures of the Aharonov-Bohm Phase in Single-Walled Carbon Nanotubes

Sasa Zaric, Gordana N. Ostojic, Junichiro Kono, Jonah Shaver, Valerie C. Moore, Michael S. Strano, Robert H. Hauge, Richard E. Smalley, and Xing Wei
Science 21 May 2004: 1129-1131.
An applied magnetic field switches short single-walled carbon nanotubes from a semiconducting to a metallic state and alters their absorption of light, in accord with theoretical predictions. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

h/e Magnetic Flux Modulation of the Energy Gap in Nanotube Quantum Dots

Ulas C. Coskun, Tzu-Chieh Wei, Smitha Vishveshwara, Paul M. Goldbart, and Alexey Bezryadin
Science 21 May 2004: 1132-1134.
An applied magnetic field switches short single-walled carbon nanotubes from a semiconducting to a metallic state and alters their absorption of light, in accord with theoretical predictions. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Infrared Spectroscopic Evidence for Protonated Water Clusters Forming Nanoscale Cages

Mitsuhiko Miyazaki, Asuka Fujii, Takayuki Ebata, and Naohiko Mikami
Science 21 May 2004: 1134-1137.
Published online 29 April 2004 [DOI: 10.1126/science.1096037] (in Science Express Reports)
An H₃O⁺ group helps stabilize nanometer-scale cages of 21 water molecules, whereas smaller clusters are chains of fewer than 10 water molecules or sheets. Abstract »|   Full Text »|   PDF »|  

Infrared Signature of Structures Associated with the H⁺(H₂O)_n (n = 6 to 27) Clusters

J.-W. Shin, N. I. Hammer, E. G. Diken, M. A. Johnson, R. S. Walters, T. D. Jaeger, M. A. Duncan, R. A. Christie, and K. D. Jordan
Science 21 May 2004: 1137-1140.
Published online 29 April 2004 [DOI: 10.1126/science.1096466] (in Science Express Reports)
An H₃O⁺ group helps stabilize nanometer-scale cages of 21 water molecules, whereas smaller clusters are chains of fewer than 10 water molecules or sheets. Abstract »|   Full Text »|   PDF »|  

Rapid Rise of Sea Level 19,000 Years Ago and Its Global Implications

Peter U. Clark, A. Marshall McCabe, Alan C. Mix, and Andrew J. Weaver
Science 21 May 2004: 1141-1144.
Marine mud rapidly filled a channel carved by rivers that drained receding glaciers in Ireland 19,000 years ago, marking a rapid rise in sea level. Abstract »|   Full Text »|   PDF »|  

Wind as a Long-Distance Dispersal Vehicle in the Southern Hemisphere

Jesús Muñoz, Ángel M. Felicísimo, Francisco Cabezas, Ana R. Burgaz, and Isabel Martínez
Science 21 May 2004: 1144-1147.
Wind patterns, not geographical proximity, best explain the distribution of lower plants in the Southern Hemisphere. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Autoimmune Disease and Impaired Uptake of Apoptotic Cells in MFG-E8-Deficient Mice

Rikinari Hanayama, Masato Tanaka, Kay Miyasaka, Katsuyuki Aozasa, Masato Koike, Yasuo Uchiyama, and Shigekazu Nagata
Science 21 May 2004: 1147-1150.
A specific protein is necessary for macrophages in the spleen and lymph nodes to engulf dead and dying cells, and autoimmune disease develops in its absence. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Discovery and Directed Evolution of a Glyphosate Tolerance Gene

Linda A. Castle, Daniel L. Siehl, Rebecca Gorton, Phillip A. Patten, Yong Hong Chen, Sean Bertain, Hyeon-Je Cho, Nicholas Duck, James Wong, Donglong Liu, and Michael W. Lassner
Science 21 May 2004: 1151-1154.
Plants were made resistant to a common herbicide by inserting a gene for a highly effective detoxifying enzyme that had been generated by direct evolution. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Disulfide-Dependent Multimeric Assembly of Resistin Family Hormones

Saurabh D. Patel, Michael W. Rajala, Luciano Rossetti, Philipp E. Scherer, and Lawrence Shapiro
Science 21 May 2004: 1154-1158.
Like its partner adiponectin, the hormone resistin is secreted from fat cells and exists in two sizes with different functions, allowing these two hormones to act as antagonists in insulin regulation. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Hereditary Early-Onset Parkinson's Disease Caused by Mutations in PINK1

Enza Maria Valente, Patrick M. Abou-Sleiman, Viviana Caputo, Miratul M. K. Muqit, Kirsten Harvey, Suzana Gispert, Zeeshan Ali, Domenico Del Turco, Anna Rita Bentivoglio, Daniel G Healy, Alberto Albanese, Robert Nussbaum, Rafael González-Maldonado, Thomas Deller, Sergio Salvi, Pietro Cortelli, William P. Gilks, David S. Latchman, Robert J. Harvey, Bruno Dallapiccola, Georg Auburger, and Nicholas W. Wood
Science 21 May 2004: 1158-1160.
Published online 15 April 2004 [DOI: 10.1126/science.1096284] (in Science Express Reports)
Mutations in a gene implicated in mitochondrial function produce a rare inherited form of Parkinson's disease by a mechanism possibly similar to that operating in common forms of the disease. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Genetic Structure of the Purebred Domestic Dog

Heidi G. Parker, Lisa V. Kim, Nathan B. Sutter, Scott Carlson, Travis D. Lorentzen, Tiffany B. Malek, Gary S. Johnson, Hawkins B. DeFrance, Elaine A. Ostrander, and Leonid Kruglyak
Science 21 May 2004: 1160-1164.
Analysis of the DNA of 85 purebred dog breeds shows that many are strongly genetically isolated and that 12 have ancient origins. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Mutational Analysis of the Tyrosine Phosphatome in Colorectal Cancers

Zhenghe Wang, Dong Shen, D. Williams Parsons, Alberto Bardelli, Jason Sager, Steve Szabo, Janine Ptak, Natalie Silliman, Brock A. Peters, Michiel S. van der Heijden, Giovanni Parmigiani, Hai Yan, Tian-Li Wang, Greg Riggins, Steven M. Powell, James K. V. Willson, Sanford Markowitz, Kenneth W. Kinzler, Bert Vogelstein, and Victor E. Velculescu
Science 21 May 2004: 1164-1166.
A large survey of colorectal cancers reveals that many have mutations in an enzyme that removes phosphates from other signaling enzymes. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

The Involvement of the Orbitofrontal Cortex in the Experience of Regret

Nathalie Camille, Giorgio Coricelli, Jerome Sallet, Pascale Pradat-Diehl, Jean-René Duhamel, and Angela Sirigu
Science 21 May 2004: 1167-1170.
Persons with a damaged orbitofrontal cortex like it when their choice in a gambling game wins, but experience no regret on learning that the alternative would have been better. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Definition of a Bacterial Type IV Secretion Pathway for a DNA Substrate

Eric Cascales and Peter J. Christie
Science 21 May 2004: 1170-1173.
The components of a protein complex on a plant bacterium work together to export its DNA into other cells, an important step in bacterial evolution and pathogenesis. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|