Cellular Invasions

Dangerous--and Not So Dangerous--Liaisons

Stella M. Hurtley and Jean Marx
Science 9 April 2004: 233.
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News

The Roots of Plant-Microbe Collaborations

Jean Marx
Science 9 April 2004: 234-236.
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Reviews

How Viruses Enter Animal Cells

Alicia E. Smith and Ari Helenius
Science 9 April 2004: 237-242.
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Bacterial Invasion: The Paradigms of Enteroinvasive Pathogens

Pascale Cossart and Philippe J. Sansonetti
Science 9 April 2004: 242-248.
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Intracellular Parasite Invasion Strategies

L. D. Sibley
Science 9 April 2004: 248-253.
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Ancient Invasions: From Endosymbionts to Organelles

Sabrina D. Dyall, Mark T. Brown, and Patricia J. Johnson
Science 9 April 2004: 253-257.
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This Week in Science

Editor summaries of this week's papers.
Science 9 April 2004: 167.
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Editorial:
A Welcome Retreat at Treasury

Donald Kennedy
Science 9 April 2004: 171.
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Editors' Choice

Highlights of the recent literature.
Science 9 April 2004: 173.
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NetWatch

Best of the Web in science.
Science 9 April 2004: 183.
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 Quarterly Author Index

Science 9 April 2004: 1-12.

 NEW PRODUCTS

Science 9 April 2004: 311.

News of the Week

SCIENCE POLITICS:
White House Rebuts Charges It Has Politicized Science

David Malakoff
Science 9 April 2004: 184-185.
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GENETICS:
Two New Asthma Genes Uncovered

Jennifer Couzin
Science 9 April 2004: 185-187.
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SCHOLARLY PUBLISHING:
U.S. Eases the Squeeze on 'Sanctioned' Authors

Yudhijit Bhattacharjee
Science 9 April 2004: 187.
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BIOETHICS:
White House Panel Issues Its Final Word on Reproductive Technology

Constance Holden
Science 9 April 2004: 188.
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DRUG SAFETY:
IOM Recommends Action on Dietary Supplements

Erik Stokstad
Science 9 April 2004: 188.
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ARCHAEOLOGY:
Burials in Cyprus Suggest Cats Were Ancient Pets

Elizabeth Pennisi
Science 9 April 2004: 189.
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FRENCH PROTEST:
Reshuffled Government Hoists the White Flag

Barbara Casassus
Science 9 April 2004: 191.
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SPANISH RESEARCH:
Win-Win Scenario: More Cash, Fewer Frigates

Xavier Bosch
Science 9 April 2004: 191.
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ScienceScope

Science 9 April 2004: 187.
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Random Samples

Science 9 April 2004: 203.
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News Focus

CELL THERAPY:
Renovating the Heart

Jennifer Couzin and Gretchen Vogel
Science 9 April 2004: 192-194.
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ARDEN L. BEMENT JR. PROFILE:
A Gentlemanly Workaholic Fills In as NSF Director

Jeffrey Mervis
Science 9 April 2004: 195.
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LUNAR AND PLANETARY SCIENCE CONFERENCE:
'Mind-Boggling' Martian Gullies Raise Climate Conundrum

Richard A. Kerr
Science 9 April 2004: 196.
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LUNAR AND PLANETARY SCIENCE CONFERENCE:
Mars Rock Crud Gets in the Way

Richard A. Kerr
Science 9 April 2004: 196-197.
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LUNAR AND PLANETARY SCIENCE CONFERENCE:
Spirit Coming Up Dry at Gusev

Richard A. Kerr
Science 9 April 2004: 197.
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EUROPEAN EXPANSION:
A Profound Tilt to the East

Martin Enserink
Science 9 April 2004: 198-201.
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EUROPEAN EXPANSION:
Outwitting TB on the E.U.'s Eastern Frontier

Martin Enserink
Science 9 April 2004: 199.
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EUROPEAN EXPANSION:
A Nanowire Link Between East and West

Fiona Proffitt
Science 9 April 2004: 201.
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Letters

This Week's Letters

Science 9 April 2004: 207.
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 U.S. Blockade of a Conference in Cuba

Steven H. Miles
Science 9 April 2004: 207.
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 Fertility Below Replacement Level

Chris Wilson
Science 9 April 2004: 207-209.
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 Parasites as a Threat to Freshwater Eels?

Bernd Sures and Klaus Knopf
Science 9 April 2004: 209-211.
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 CORRECTIONS AND CLARIFICATIONS

Science 9 April 2004: 211.
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Books et al.

PHYSICS:
Untangling the Universe

James Trefil
Science 9 April 2004: 212.
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HISTORY OF SCIENCE:
Knowledge, Wisdom, and Luck

Cristina González
Science 9 April 2004: 213.
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 Books Received

Science 9 April 2004: 213.

Policy Forum

ETHICS:
Enhanced: Constructing Ethical Guidelines for Biohistory

Lori B. Andrews, Nancy Buenger, Jennifer Bridge, Laurie Rosenow, David Stoney, R. E. Gaensslen, Theodore Karamanski, Russell Lewis, Jordan Paradise, Amy Inlander, and David Gonen
Science 9 April 2004: 215-216.
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Perspectives

PHYSIOLOGY:
Power at the Tip of the Tongue

Ulrike K. Müller and Sander Kranenbarg
Science 9 April 2004: 217-219.
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ATMOSPHERIC SCIENCE:
In Search of Paleo-ENSO

Yair Rosenthal and Anthony J. Broccoli
Science 9 April 2004: 219-221.
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MATERIALS SCIENCE:
Understanding How Nanocrystalline Metals Deform

Kevin J. Hemker
Science 9 April 2004: 221-223.
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BIOCHEMISTRY:
Oily Barbarians Breach Ion Channel Gates

Donald W. Hilgemann
Science 9 April 2004: 223-224.
Published online 18 March 2004 [DOI: 10.1126/science.1097439] (in Science Express Perspectives)
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Brevia

 Early Taming of the Cat in Cyprus

J.-D. Vigne, J. Guilaine, K. Debue, L. Haye, and P. Gérard
Science 9 April 2004: 259.
A cat found buried next to a human in Cyprus suggests that felines were first domesticated there 9500 years ago, rather than thousands of years later in Egypt. Full Text »|   PDF »|   Supporting Online Material »|  

Research Articles

Quantifying Stratospheric Ozone in the Upper Troposphere with in Situ Measurements of HCl

T. P. Marcy, D. W. Fahey, R. S. Gao, P. J. Popp, E. C. Richard, T. L. Thompson, K. H. Rosenlof, E. A. Ray, R. J. Salawitch, C. S. Atherton, D. J. Bergmann, B. A. Ridley, A. J. Weinheimer, M. Loewenstein, E. M. Weinstock, and M. J. Mahoney
Science 9 April 2004: 261-265.
Aircraft measurements of hydrochloric acid, a proxy for ozone, show that significant amounts of ozone can be transported into the upper troposphere. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Functional Conversion Between A-Type and Delayed Rectifier K⁺ Channels by Membrane Lipids

Dominik Oliver, Cheng-Chang Lien, Malle Soom, Thomas Baukrowitz, Peter Jonas, and Bernd Fakler
Science 9 April 2004: 265-270.
Published online 18 March 2004 [DOI: 10.1126/science.1094113] (in Science Express Research Articles)
Distinct ion pores in cell membranes are actually versions of a single pore altered by nearby lipids, not the products of different genes. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Reports

Real-Time Quantum Feedback Control of Atomic Spin-Squeezing

JM Geremia, John K. Stockton, and Hideo Mabuchi
Science 9 April 2004: 270-273.
Observation and immediate adjustment of angular momentum in a cloud of cold atoms allows highly accurate measurement and control of quantum states. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Plastic Deformation with Reversible Peak Broadening in Nanocrystalline Nickel

Zeljka Budrovic, Helena Van Swygenhoven, Peter M. Derlet, Steven Van Petegem, and Bernd Schmitt
Science 9 April 2004: 273-276.
Slow deformation of nanocrystalline nickel is reversible, avoiding the formation of new defects that weaken coarsely crystalline samples. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Direct Spinning of Carbon Nanotube Fibers from Chemical Vapor Deposition Synthesis

Ya-Li Li, Ian A. Kinloch, and Alan H. Windle
Science 9 April 2004: 276-278.
Published online 11 March 2004 [DOI: 10.1126/science.1094982] (in Science Express Reports)
Nanotube fibers can be spun into a long string as they are withdrawn from the reaction zone of a furnace that contains a liquid carbon source and an iron catalyst. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Reversible Optical Transcription of Supramolecular Chirality into Molecular Chirality

Jaap J. D. de Jong, Linda N. Lucas, Richard M. Kellogg, Jan H. van Esch, and Ben L. Feringa
Science 9 April 2004: 278-281.
Light or temperature changes can induce a large self-assembled helical structure to reflect the chiral state of a single component molecule. Abstract »|   Full Text »|   PDF »|  

Controlled Atomic Doping of a Single C₆₀ Molecule

R. Yamachika, M. Grobis, A. Wachowiak, and M. F. Crommie
Science 9 April 2004: 281-284.
Published online 11 March 2004 [DOI: 10.1126/science.1095069] (in Science Express Reports)
Up to four potassium atoms can be added one by one to C₆₀ with the tip of a scanning tunneling microscope, allowing detailed measurements of each molecule in the sequence. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Enigmatic Biodiversity Correlations: Ant Diversity Responds to Diverse Resources

Inge Armbrecht, Ivette Perfecto, and John Vandermeer
Science 9 April 2004: 284-286.
Collections of twigs from different tree species can support more species of ants than can twigs from a single species, even though the ants are not specialist consumers. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Tip20p Prohibits Back-Fusion of COPII Vesicles with the Endoplasmic Reticulum

Faustin Kamena and Anne Spang
Science 9 April 2004: 286-289.
A protein that blocks vesicles from fusing with their parent membranes prevents intracellular membrane traffic from slipping backward. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Transmembrane Segments of Syntaxin Line the Fusion Pore of Ca²+-Triggered Exocytosis

Xue Han, Chih-Tien Wang, Jihong Bai, Edwin R. Chapman, and Meyer B. Jackson
Science 9 April 2004: 289-292.
Published online 11 March 2004 [DOI: 10.1126/science.1095801] (in Science Express Reports)
Multiple copies of a protein are found to line the previously undefined pore that forms when a secretory vesicle fuses with the cell membrane in the process of expelling its contents. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Protection from Cardiac Arrhythmia Through Ryanodine Receptor-Stabilizing Protein Calstabin2

Xander H. T. Wehrens, Stephan E. Lehnart, Steven R. Reiken, Shi-Xian Deng, John A. Vest, Daniel Cervantes, James Coromilas, Donald W. Landry, and Andrew R. Marks
Science 9 April 2004: 292-296.
A drug that inhibits abnormal leakage of calcium ions into heart cells prevents cardiac arrythmias in a mouse model. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Hemocyte-Mediated Shell Mineralization in the Eastern Oyster

Andrew S. Mount, A. P. Wheeler, Rajesh P. Paradkar, and D. Snider
Science 9 April 2004: 297-300.
Oyster shells are assembled from calcite particles made in circulating immune cells, not formed on the growing shells themselves. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Characterization of a Common Susceptibility Locus for Asthma-Related Traits

Tarja Laitinen, Anne Polvi, Pia Rydman, Johanna Vendelin, Ville Pulkkinen, Paula Salmikangas, Siru Mäkelä, Marko Rehn, Asta Pirskanen, Anna Rautanen, Marco Zucchelli, Harriet Gullstén, Marina Leino, Harri Alenius, Tuula Petäys, Tari Haahtela, Annika Laitinen, Catherine Laprise, Thomas J. Hudson, Lauri A. Laitinen, and Juha Kere
Science 9 April 2004: 300-304.
A gene for a cell surface receptor likely confers susceptibility to asthma and allergy in three groups of patients from Canada and Finland. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

The Ashbya gossypii Genome as a Tool for Mapping the Ancient Saccharomyces cerevisiae Genome

Fred S. Dietrich, Sylvia Voegeli, Sophie Brachat, Anita Lerch, Krista Gates, Sabine Steiner, Christine Mohr, Rainer Pöhlmann, Philippe Luedi, Sangdun Choi, Rod A. Wing, Albert Flavier, Thomas D. Gaffney, and Peter Philippsen
Science 9 April 2004: 304-307.
Published online 4 March 2004 [DOI: 10.1126/science.1095781] (in Science Express Reports)
Comparison of the sequence of laboratory yeast to that of a distant relative, a small filamentous fungus, reveals that yeast evolved via genome duplication and separate evolution of homologous genes. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Neuronal Activity Related to Reward Value and Motivation in Primate Frontal Cortex

Matthew R. Roesch and Carl R. Olson
Science 9 April 2004: 307-310.
An experiment that distinguishes between expectation of a reward's value and motivational state shows that these two are encoded by different regions of the brain. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Technical Comments

 Comment on "Cerebellar LTD and Learning-Dependent Timing of Conditioned Eyelid Responses"

Kimberly M. Christian, Andrew M. Poulos, David G. Lavond, and Richard F. Thompson
Science 9 April 2004: 211.
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 Response to Comment on "Cerebellar LTD and Learning-Dependent Timing of Conditioned Eyelid Responses"

C. I. De Zeeuw, Y. Elgersma, H. C. Hulscher, B. R. Dortland, R. A. Hensbroek, T. J. H. Ruigrok, and S. K. E. Koekkoek
Science 9 April 2004: 211.
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