This Week in Science

Editor summaries of this week's papers.
Science 10 January 2003: 161.
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Editorial:
Rebalancing Teaching and Research

Thomas R. Cech
Science 10 January 2003: 165.
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Editors' Choice

Highlights of the recent literature.
Science 10 January 2003: 167.
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NetWatch

Best of the Web in science.
Science 10 January 2003: 179.
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 Quarterly Author Index

Science 10 January 2003: 1-17.

 NEW PRODUCTS

Science 10 January 2003: 268-269.

News of the Week

SPACE SCIENCE:
Human Flight Is Next Step for China's Space Program

Ding Yimin and Dennis Normile
Science 10 January 2003: 180.
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RESEARCH FUNDING:
Expert Panel Urges a Boost for Smithsonian Science

Jennifer Couzin
Science 10 January 2003: 180.
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BIOTERRORISM:
New Look at Old Data Irks Smallpox-Eradication Experts

Martin Enserink
Science 10 January 2003: 181.
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ASTRONOMY:
Surveys Spot Ring Around the Milky Way

Robert Irion
Science 10 January 2003: 183.
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PALEOCLIMATE:
Tropical Pacific a Key to Deglaciation

Richard A. Kerr
Science 10 January 2003: 183-184.
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NATIONAL LABORATORIES:
UC Ties at Stake in Los Alamos Shakeup

David Malakoff
Science 10 January 2003: 184.
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PHYSICS:
Relativity Goes Where Einstein Sneered to Tread

Charles Seife
Science 10 January 2003: 185.
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NATIONAL INSTITUTES OF HEALTH:
Clinical Recruitment Stumbles on a Logo

Jocelyn Kaiser and Jon Cohen
Science 10 January 2003: 187.
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RESEARCH POLICY:
A New Road for Indian Science

Pallava Bagla
Science 10 January 2003: 187.
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ScienceScope

Science 10 January 2003: 183.
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Random Samples

Science 10 January 2003: 197.
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News Focus

ASIAN MEDICINE:
The New Face of Traditional Chinese Medicine

Dennis Normile
Science 10 January 2003: 188-190.
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NEW PERSPECTIVES FOR PRION THERAPEUTICS MEETING:
Prion Disease Treatment's Early Promise Unravels

Peter Follette
Science 10 January 2003: 191-192.
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INTERNATIONAL SOCIETY FOR INTELLIGENCE RESEARCH MEETING:
The Practical Benefits of General Intelligence

Constance Holden
Science 10 January 2003: 192-193.
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BIOMEDICAL POLICY:
Shrugging Off Doubters, NIH Launches a New Institute

Jocelyn Kaiser
Science 10 January 2003: 193-194.
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DEEP-SEA SCIENCE:
Cool Corals Become Hot Topic

David Malakoff
Science 10 January 2003: 195.
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Letters

This Week's Letters

Science 10 January 2003: 201.
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 Revisiting Nuclear Power Plant Safety

Frank N. von Hippel;, David J. Brenner;, Edwin S. Lyman;, Douglas M. Chapin, Karl P. Cohen, W. Kenneth Davis, Edwin E. Kintner, Leonard J. Koch, John W. Landis, Milton Levenson, I. Harry Mandil, Zack T. Pate, Theodore Rockwell, Alan Schriesheim, John W. Simpson, Alexander Squire, Chauncey Starr, Henry E. Stone, John J. Taylor, Neil E. Todreas, Bertram Wolfe, and Edwin L. Zebroski
Science 10 January 2003: 201-203.
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Books et al.

ARCHAEOLOGY:
Adventures of a Pioneer Mayanist

David Webster
Science 10 January 2003: 204-205.
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MEDICINE:
Alternative Approaches to Healing

Susan E. Lederer
Science 10 January 2003: 205.
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 Books Received

Science 10 January 2003: 205.

Policy Forum

PUBLIC HEALTH:
Toward Evidence-Based Health Claims for Foods

Martijn B. Katan and Nicole M. de Roos
Science 10 January 2003: 206-207.
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Perspectives

DEVELOPMENT:
Lymphatics Make the Break

Rakesh K. Jain and Timothy P. Padera
Science 10 January 2003: 209-210.
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APPLIED PHYSICS:
Enhanced: Moore's Law Forever?

Mark Lundstrom
Science 10 January 2003: 210-211.
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CIRCADIAN RHYTHMS:
Circadian Photoreception

Michael Menaker
Science 10 January 2003: 213-214.
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APOPTOSIS:
Life and Death Decisions

Donald W. Nicholson and Nancy A. Thornberry
Science 10 January 2003: 214-215.
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CLIMATE CHANGE:
Whither Arctic Climate?

Drew Shindell
Science 10 January 2003: 215-216.
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Review

From Anchovies to Sardines and Back: Multidecadal Change in the Pacific Ocean

Francisco P. Chavez, John Ryan, Salvador E. Lluch-Cota, and Miguel Ñiquen C.
Science 10 January 2003: 217-221.
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Brevia

 Reduced Pupillary Light Responses in Mice Lacking Cryptochromes

Russell N. Van Gelder, Raymond Wee, Janet A. Lee, and Daniel C. Tu
Science 10 January 2003: 222.
A component of the circadian clock also contributes to non-image forming light responses such as dilation of the pupils. Full Text »|   PDF »|   Supporting Online Material »|  

Research Article

Distinctive Roles of PHAP Proteins and Prothymosin- in a Death Regulatory Pathway

Xuejun Jiang, Hyun-Eui Kim, Hongjun Shu, Yingming Zhao, Haichao Zhang, James Kofron, Jennifer Donnelly, Dave Burns, Shi-chung Ng, Saul Rosenberg, and Xiaodong Wang
Science 10 January 2003: 223-226.
A newly discovered molecule initiates a cascade that activates caspase-9, a protease responsible for the death of certain cell types. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Reports

Nanoparticle Assembly and Transport at Liquid-Liquid Interfaces

Y. Lin, H. Skaff, T. Emrick, A. D. Dinsmore, and T. P. Russell
Science 10 January 2003: 226-229.
Very tiny nanoparticles confined at fluid-fluid interfaces can self-assemble and be induced by light to migrate across the interface. Abstract »|   Full Text »|   PDF »|  

Quantum Phase Transition in Organic Charge-Transfer Complexes

Sachio Horiuchi, Yoichi Okimoto, Reiji Kumai, and Yoshinori Tokura
Science 10 January 2003: 229-232.
An unusual charge-transfer salt complex allows the control of quantum phase transitions by external pressure. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Bose-Einstein Condensation of Cesium

Tino Weber, Jens Herbig, Michael Mark, Hanns-Christoph Nägerl, and Rudolf Grimm
Science 10 January 2003: 232-235.
Published online 5 December 2002 [DOI: 10.1126/science.1079699] (in Science Express Reports)
Optical and magnetic trapping techniques yield a Bose-Einstein condensate of cesium. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Anthropogenic CO₂ Uptake by the Ocean Based on the Global Chlorofluorocarbon Data Set

Ben I. McNeil, Richard J. Matear, Robert M. Key, John L. Bullister, and Jorge L. Sarmiento
Science 10 January 2003: 235-239.
Observations on oceanic uptake of trace gases (chlorofluorocarbons) during the past two decades yield improved estimates of how much anthropogenic CO₂ is absorbed. Abstract »|   Full Text »|   PDF »|  

Satellite Observations of Magnetic Fields Due to Ocean Tidal Flow

Robert H. Tyler, Stefan Maus, and Hermann Lühr
Science 10 January 2003: 239-241.
Geomagnetic distortions produced by ocean movements can be measured by satellites, yielding more precise monitoring of tidal and other currents. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Dispersal, Environment, and Floristic Variation of Western Amazonian Forests

Hanna Tuomisto, Kalle Ruokolainen, and Markku Yli-Halla
Science 10 January 2003: 241-244.
A large data set shows that plant distribution in a tropical forest is more dependent on climate and soil type than on dispersal capacity. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Diminished Pupillary Light Reflex at High Irradiances in Melanopsin-Knockout Mice

R. J. Lucas, S. Hattar, M. Takao, D. M. Berson, R. G. Foster, and K.-W. Yau
Science 10 January 2003: 245-247.
Melanopsin, a photosensitive pigment found in some retinal ganglion cells, contributes to non-image forming responses to light such as pupil dilation. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Regulation of Blood and Lymphatic Vascular Separation by Signaling Proteins SLP-76 and Syk

Farhad Abtahian, Anastasia Guerriero, Eric Sebzda, Min-Min Lu, Rong Zhou, Attila Mocsai, Erin E. Myers, Bin Huang, David G. Jackson, Victor A. Ferrari, Victor Tybulewicz, Clifford A. Lowell, John J. Lepore, Gary A. Koretzky, and Mark L. Kahn
Science 10 January 2003: 247-251.
Two signaling proteins are responsible for segregating the two major vascular networks (lymph and circulatory system) during development in mammals. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

KCNQ1 Gain-of-Function Mutation in Familial Atrial Fibrillation

Yi-Han Chen, Shi-Jie Xu, Saïd Bendahhou, Xiao-Liang Wang, Ying Wang, Wen-Yuan Xu, Hong-Wei Jin, Hao Sun, Xiao-Yan Su, Qi-Nan Zhuang, Yi-Qing Yang, Yue-Bin Li, Yi Liu, Hong-Ju Xu, Xiao-Fei Li, Ning Ma, Chun-Ping Mou, Zhu Chen, Jacques Barhanin, and Wei Huang
Science 10 January 2003: 251-254.
A faulty potassium channel can cause atrial fibrillation, a common heart arrythmia. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Ringlike Structure of the Deinococcus radiodurans Genome: A Key to Radioresistance?

Smadar Levin-Zaidman, Joseph Englander, Eyal Shimoni, Ajay K. Sharma, Kenneth W. Minton, and Abraham Minsky
Science 10 January 2003: 254-256.
The secret of a bacterium's extraordinary resistance to radiation damage may lie in the tightly toroidal structure of its genome, not a special repair mechanism. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Mutations in the DJ-1 Gene Associated with Autosomal Recessive Early-Onset Parkinsonism

Vincenzo Bonifati, Patrizia Rizzu, Marijke J. van Baren, Onno Schaap, Guido J. Breedveld, Elmar Krieger, Marieke C. J. Dekker, Ferdinando Squitieri, Pablo Ibanez, Marijke Joosse, Jeroen W. van Dongen, Nicola Vanacore, John C. van Swieten, Alexis Brice, Giuseppe Meco, Cornelia M. van Duijn, Ben A. Oostra, and Peter Heutink
Science 10 January 2003: 256-259.
Published online 21 November 2002 [DOI: 10.1126/science.1077209] (in Science Express Reports)
Mutations in a gene that may be involved in cellular resistance to oxidants is associated with early Parkinsonian symptoms in two families. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Dyskeratosis Congenita and Cancer in Mice Deficient in Ribosomal RNA Modification

Davide Ruggero, Silvia Grisendi, Francesco Piazza, Eduardo Rego, Francesca Mari, Pulivarthi H. Rao, Carlos Cordon-Cardo, and Pier Paolo Pandolfi
Science 10 January 2003: 259-262.
A mouse study reveals that defects in ribosomal RNA can lead to bone marrow failure and cancer. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Role of a Highly Conserved Bacterial Protein in Outer Membrane Protein Assembly

Romé Voulhoux, Martine P. Bos, Jeroen Geurtsen, Maarten Mols, and Jan Tommassen
Science 10 January 2003: 262-265.
A homolog of the gene responsible for importing proteins into plant chloroplasts helps assemble proteins of the outer membranes of Gram-negative bacteria. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Drosophila BLM in Double-Strand Break Repair by Synthesis-Dependent Strand Annealing

Melissa D. Adams, Mitch McVey, and Jeff J. Sekelsky
Science 10 January 2003: 265-267.
The Drosophila version of the gene for Bloom's Syndrome, in which patients have a predisposition to cancer, repairs double-stranded DNA breaks. Abstract »|   Full Text »|   PDF »|   Supporting Online Material »|  

Technical Comments

 Comment on "Otolith ¹⁸O Record of Mid-Holocene Sea Surface Temperatures in Peru"

Philippe Béarez, Thomas J. DeVries, and Luc Ortlieb
Science 10 January 2003: 203.
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 Response to Comment on "Otolith ¹⁸O Record of Mid-Holocene Sea Surface Temperatures in Peru"

C. Fred T. Andrus, Douglas E. Crowe, Daniel H. Sandweiss, Elizabeth J. Reitz, Christopher S. Romanek, and Kirk A. Maasch
Science 10 January 2003: 203.
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