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COVER Complex diseases, such as heart disease, diabetes, and cancer, are among the most common and costly illnesses in Westernized countries. The special section in this issue considers the challenges of sorting out the multiple factors--including lifestyle, diet, infectious agents, and a host of genes--that contribute to disease susceptibility. 685 [Photo illustration: Ann Cutting]

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Science. ISSN 0036-8075 (print), 1095-9203 (online)