Breakthrough of the Year

News

BREAKTHROUGH OF THE YEAR:
Genomics Comes of Age

Elizabeth Pennisi
Science 22 December 2000: 2220-2221.
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BREAKTHROUGH OF THE YEAR:
The Runners-Up

The News and Editorial Staffs
Science 22 December 2000: 2221-2225.
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BREAKTHROUGH OF THE YEAR:
Peering Into 2001

Science 22 December 2000: 2222.
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BREAKTHROUGH OF THE YEAR:
Scorecard '99

Science 22 December 2000: 2223.
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DISAPPEARING DISCOVERY OF THE YEAR:
Archaeoraptor

Science 22 December 2000: 2224.
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MELTDOWN OF THE YEAR:
The Wen Ho Lee Case

Science 22 December 2000: 2224.
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CONTROVERSY OF THE YEAR:
Biomedical Ethics on the Front Burner

Science 22 December 2000: 2225.
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This Week in Science

Editor summaries of this week's papers.
Science 22 December 2000: 2209.
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Editorial:
Breakthrough of the Year

Donald Kennedy
Science 22 December 2000: 2255.
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Editors' Choice

Highlights of the recent literature.
Science 22 December 2000: 2213.
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NetWatch

Best of the Web in science.
Science 22 December 2000: 2207.
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 AAAS News & Notes

Science 22 December 2000: 2327-2328.

 NEW PRODUCTS

Science 22 December 2000: 2329-2330.

News of the Week

2001 SPENDING:
NIH Gets $2.5 Billion More as Congress Wraps Up Budget

David Malakoff
Science 22 December 2000: 2226.
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AFFIRMATIVE ACTION:
Court Backs Michigan Policy on Diversity

Constance Holden
Science 22 December 2000: 2227.
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CELL BIOLOGY:
Disease Genes Clarify Cholesterol Trafficking

Jean Marx
Science 22 December 2000: 2227-2229.
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SOUTHERN EUROPE:
European Union to Fund Science in Balkan Region

Richard Stone
Science 22 December 2000: 2230.
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ECOLOGY:
Silk Moth Deaths Show Perils of Biocontrol

Mari N. Jensen
Science 22 December 2000: 2230-2231.
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MICROBIOLOGY:
Fighting Bacterial Fire With Bacterial Fire

Evelyn Strauss
Science 22 December 2000: 2231-2233.
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LABORATORY ANIMALS:
Congress OKs Plan for Retired Chimps

Gretchen Vogel
Science 22 December 2000: 2233.
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NEUROSCIENCE:
Neural Net Contest Draws Online Crowd

John S. MacNeil
Science 22 December 2000: 2233.
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ScienceScope

Science 22 December 2000: 2229.
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Random Samples

Science 22 December 2000: 2249.
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News Focus

SCIENCE POLICY:
Clinton's Science Legacy: Ending on a High Note

David Malakoff
Science 22 December 2000: 2234-2236.
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AN INTERVIEW WITH THE PRESIDENT:
"I'd Like to See America Used as a Global Lab"

Science 22 December 2000: 2236-2239.
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GEOLOGICAL SOCIETY OF AMERICA MEETING:
Geologists Pursue Solar System's Oldest Relics

Richard A. Kerr
Science 22 December 2000: 2239-2242.
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NEUROBIOLOGY:
The Come-Hither, Don't-Touch-Me Proteins

Gretchen Vogel
Science 22 December 2000: 2243-2244.
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MOLECULAR CELL BIOLOGY:
A Powerhouse Rises in Reborn Dresden

Robert Koenig
Science 22 December 2000: 2244.
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MICROBIOLOGY:
Simple Hosts May Help Reveal How Bacteria Infect Cells

Evelyn Strauss
Science 22 December 2000: 2245-2247.
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Letters

This Week's Letters

Science 22 December 2000: 2257.
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 Penny Wise, Pound Foolish--A Retrospective

Laura Manuelidis
Science 22 December 2000: 2257.
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 Missing Persons Identification: Genetics at Work for Society

Jose A. Lorente, Carmen Entrala, J. Carlos Alvarez, Miguel Lorente, Enrique Villanueva, Félix Carrasco, and Bruce Budowle
Science 22 December 2000: 2257-2258.
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 Eurasian Air Pollution Reaches Eastern North America

Pierre E. Biscaye, Francis E. Grousset, Anders M. Svensson, Aloys Bory;, and Leonard A. Barrie
Science 22 December 2000: 2258-2259.
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 Careful Planning Created the Society for Neuroscience

Louise H. Marshall
Science 22 December 2000: 2259.
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 The Vulnerability of Venice

Vivien Gornitz, Rhodes W. Fairbridge;, Albert J. Ammerman, and Charles E. McClennen
Science 22 December 2000: 2259-2260.
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 The Other Stanley Cohen

Ruth Hogue Angeletti
Science 22 December 2000: 2260.
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Books et al.

FICTION:
Rhetoric and the Math Melodrama

David Foster Wallace
Science 22 December 2000: 2263-2267.
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 Books Received

Science 22 December 2000: 2263.

Policy Forum

MEDICINE:
Communicating Statistical Information

Ulrich Hoffrage, Samuel Lindsey, Ralph Hertwig, and Gerd Gigerenzer
Science 22 December 2000: 2261-2262.
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Perspectives

COGNITION:
The Manifold Ways of Perception

H. Sebastian Seung and Daniel D. Lee
Science 22 December 2000: 2268-2269.
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MICROELECTRONICS:
Flip the Chip

C. P. Wong, Shijian Luo, and Zhuqing Zhang
Science 22 December 2000: 2269-2270.
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NEUROBIOLOGY:
Enhanced: A Stargazer Foretells the Way to the Synapse

Terunaga Nakagawa and Morgan Sheng
Science 22 December 2000: 2270-2271.
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CELL CYCLE:
License Withheld--Geminin Blocks DNA Replication

Zoi Lygerou and Paul Nurse
Science 22 December 2000: 2271-2273.
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QUANTUM CRYPTOGRAPHY:
Single Photons "on Demand"

Simon Benjamin
Science 22 December 2000: 2273-2274.
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PALEOCLIMATE:
The Amazon Reveals Its Secrets--Partly

Julio L. Betancourt
Science 22 December 2000: 2274-2275.
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NEUROSCIENCE:
Boosting Working Memory

Trevor W. Robbins, Mitul A. Mehta, and Barbara J. Sahakian
Science 22 December 2000: 2275-2276.
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Reports

Intersubband Electroluminescence from Silicon-Based Quantum Cascade Structures

G. Dehlinger, L. Diehl, U. Gennser, H. Sigg, J. Faist, K. Ensslin, D. Grützmacher, and E. Müller
Science 22 December 2000: 2277-2280.
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Element-Selective Single Atom Imaging

K. Suenaga, M. Tencé, C. Mory, C. Colliex, H. Kato, T. Okazaki, H. Shinohara, K. Hirahara, S. Bandow, and S. Iijima
Science 22 December 2000: 2280-2282.
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A Quantum Dot Single-Photon Turnstile Device

P. Michler, A. Kiraz, C. Becher, W. V. Schoenfeld, P. M. Petroff, Lidong Zhang, E. Hu, and A. Imamoglu
Science 22 December 2000: 2282-2285.
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Reconstruction of the Amazon Basin Effective Moisture Availability over the Past 14,000 Years

Mark A. Maslin and Stephen J. Burns
Science 22 December 2000: 2285-2287.
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Upwelling Intensification As Part of the Pliocene-Pleistocene Climate Transition

Jeremy R. Marlow, Carina B. Lange, Gerold Wefer, and Antoni Rosell-Melé
Science 22 December 2000: 2288-2291.
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Millennial-Scale Dynamics of Southern Amazonian Rain Forests

Francis E. Mayle, Rachel Burbridge, and Timothy J. Killeen
Science 22 December 2000: 2291-2294.
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Transmembrane Molecular Pump Activity of Niemann-Pick C1 Protein

Joanna P. Davies, Fannie W. Chen, and Yiannis A. Ioannou
Science 22 December 2000: 2295-2298.
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Identification of HE1 as the Second Gene of Niemann-Pick C Disease

Saule Naureckiene, David. E. Sleat, Henry Lackland, Anthony Fensom, Marie T. Vanier, Robert Wattiaux, Michel Jadot, and Peter Lobel
Science 22 December 2000: 2298-2301.
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Evidence for Genetic Linkage of Alzheimer's Disease to Chromosome 10q

Lars Bertram, Deborah Blacker, Kristina Mullin, Devon Keeney, Jennifer Jones, Sanjay Basu, Stephen Yhu, Melvin G. McInnis, Rodney C. P. Go, Konstantinos Vekrellis, Dennis J. Selkoe, Aleister J. Saunders, and Rudolph E. Tanzi
Science 22 December 2000: 2302-2303.
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Linkage of Plasma A42 to a Quantitative Locus on Chromosome 10 in Late-Onset Alzheimer's Disease Pedigrees

Nilufer Ertekin-Taner, Neill Graff-Radford, Linda H. Younkin, Christopher Eckman, Matthew Baker, Jennifer Adamson, James Ronald, John Blangero, Michael Hutton, and Steven G. Younkin
Science 22 December 2000: 2303-2304.
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Susceptibility Locus for Alzheimer's Disease on Chromosome 10

Amanda Myers, Peter Holmans, Helen Marshall, Jennifer Kwon, David Meyer, Dzanan Ramic, Shantia Shears, Jeremy Booth, Fabienne Wavrant DeVrieze, Richard Crook, Marian Hamshere, Richard Abraham, Nigel Tunstall, Francis Rice, Stephanie Carty, Sara Lillystone, Pat Kehoe, Varuni Rudrasingham, Lesley Jones, Simon Lovestone, Jordi Perez-Tur, Julie Williams, Michael J. Owen, John Hardy, and Alison M. Goate
Science 22 December 2000: 2304-2305.
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Genome-Wide Location and Function of DNA Binding Proteins

Bing Ren, François Robert, John J. Wyrick, Oscar Aparicio, Ezra G. Jennings, Itamar Simon, Julia Zeitlinger, Jörg Schreiber, Nancy Hannett, Elenita Kanin, Thomas L. Volkert, Christopher J. Wilson, Stephen P. Bell, and Richard A. Young
Science 22 December 2000: 2306-2309.
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Inhibition of Eukaryotic DNA Replication by Geminin Binding to Cdt1

James A. Wohlschlegel, Brian T. Dwyer, Suman K. Dhar, Christin Cvetic, Johannes C. Walter, and Anindya Dutta
Science 22 December 2000: 2309-2312.
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Distinct Roles for TBP and TBP-Like Factor in Early Embryonic Gene Transcription in Xenopus

Gert Jan C. Veenstra, Daniel L. Weeks, and Alan P. Wolffe
Science 22 December 2000: 2312-2315.
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Cholinergic Enhancement and Increased Selectivity of Perceptual Processing During Working Memory

Maura L. Furey, Pietro Pietrini, and James V. Haxby
Science 22 December 2000: 2315-2319.
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A Global Geometric Framework for Nonlinear Dimensionality Reduction

Joshua B. Tenenbaum, Vin de Silva, and John C. Langford
Science 22 December 2000: 2319-2323.
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Nonlinear Dimensionality Reduction by Locally Linear Embedding

Sam T. Roweis and Lawrence K. Saul
Science 22 December 2000: 2323-2326.
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