COVER These children in Mtubatuba, South Africa, will be growing up in a country where HIV infection rates are soaring. Their future, like that of children throughout much of sub-Saharan Africa, is clouded by the social, economic, and political consequences of the HIV/AIDS epidemic. A special section, beginning on page 2149, looks at AIDS research in Africa, the researchers who are conducting it, and the policy challenges that must be faced to blunt the epidemic. [Photo: Malcolm Linton]

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