Breakthrough of the Year

News

BREAKTHROUGH OF THE YEAR:
Capturing the Promise of Youth

Gretchen Vogel
Science 17 December 1999: 2238-2239.
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BREAKTHROUGH OF THE YEAR:
The Runners-Up

The News and Editorial Staffs
Science 17 December 1999: 2239-2243.
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BREAKTHROUGH OF THE YEAR:
Peering Into 2000

Science 17 December 1999: 2240.
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BREAKTHROUGH OF THE YEAR:
Scorecard '98

Science 17 December 1999: 2241.
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BLUNDER OF THE YEAR:
NASA Tangles With the Metric System

Science 17 December 1999: 2241.
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BREAKDOWN OF THE YEAR:
Creationists Win in Kansas

Constance Holden
Science 17 December 1999: 2242.
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CONTROVERSY OF THE YEAR:
GM Foods Under Attack

Science 17 December 1999: 2243.
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This Week in Science

Editor summaries of this week's papers.
Science 17 December 1999: 2229.
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 Editorial:
Breakthroughs 1999

Floyd E. Bloom
Science 17 December 1999: 2267.
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Editors' Choice

Highlights of the recent literature.
Science 17 December 1999: 1.
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NetWatch

Best of the Web in science.
Science 17 December 1999: 2227.
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 NEW PRODUCTS

Science 17 December 1999: 2367-2368.

News of the Week

CLINICAL TRIALS:
Gene Therapy Death Prompts Review of Adenovirus Vector

Eliot Marshall
Science 17 December 1999: 2244-2245.
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MICROBIOLOGY:
Promising Antibiotic Candidate Identified

Martin Enserink
Science 17 December 1999: 2245-2247.
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SPACE:
Europe Lofts X-ray Observatory

Alexander Hellemans
Science 17 December 1999: 2247-2248.
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NIMH:
Mental Health Agency Shrugs Off Critics

Constance Holden
Science 17 December 1999: 2248.
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MARS EXPLORATION:
Changes to Missions Could Delay Science

Andrew Lawler and Richard Kerr
Science 17 December 1999: 2248-2249.
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SCIENTIFIC MISCONDUCT:
Researcher Rebuked for 20-Year-Old Misdeed

Michael Hagmann
Science 17 December 1999: 2249-2250.
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COMPUTER SCIENCE:
Big Blue Aims to Crack Protein Riddle

Robert F. Service
Science 17 December 1999: 2250.
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NASA:
NRC Panel to Propose Station Institute

Andrew Lawler
Science 17 December 1999: 2251.
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PCR:
Taq Polymerase Patent Ruled Invalid

Robert F. Service
Science 17 December 1999: 2251-2253.
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LAB SAFETY:
Licenses Suspended at 3 Toronto Hospitals

Wayne Kondro
Science 17 December 1999: 2253.
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ScienceScope

Science 17 December 1999: 2247.
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Random Samples

Science 17 December 1999: 2265.
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News Focus

GEOPHYSICS:
Ancient Continent Opens Window on the Early Earth

Carl Zimmer
Science 17 December 1999: 2254-2256.
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BIOMEDICINE:
Does Cancer Therapy Trigger Cell Suicide?

Elizabeth Finkel
Science 17 December 1999: 2256-2258.
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SCIENTIFIC MISCONDUCT:
Europe Stresses Prevention Rather Than Cure

Michael Hagmann
Science 17 December 1999: 2258-2259.
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SPACE SCIENCE:
Indian Agency Eyes Moon in Shift Toward Research

Pallava Bagla
Science 17 December 1999: 2260.
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BIOLOGICAL IMAGING:
Scanners Get a Fix on Lab Animals

Robert F. Service
Science 17 December 1999: 2261-2263.
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Letters

This Week's Letters

Science 17 December 1999: 2269.
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 A Loss to Science

Robert J. Birgeneau
Science 17 December 1999: 2269.
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 Dietary Supplements: What Is in the Public's Best Interest?

John N. Hathcock;, Shawn M. Talbott;, and Steven H. Zeisel
Science 17 December 1999: 2269.
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 Scrutinizing Creativity

Dennis Hollenberg;, Jacob Goldenberg, David Mazursky, and Sorin Solomon
Science 17 December 1999: 2269.
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 A Comb-Wide Web

J³rgen Tautz
Science 17 December 1999: 2269.
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 CORRECTIONS AND CLARIFICATIONS

Science 17 December 1999: 2269.
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Books et al.

HISTORY OF SCIENCE:
Cathedrals as Astronomical Instruments

Albert Van Helden
Science 17 December 1999: 2279-2280.
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ENERGY TECHNOLOGY:
A Bright View, Too Focused

David Faiman
Science 17 December 1999: 2280.
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Policy Forum

FOOD SAFETY:
Food Irradiation--The Neglected Solution to Food-Borne Illness

Randall Lutter
Science 17 December 1999: 2275-2276.
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GENETIC TECHNOLOGIES:
Commercialization of Genetic Research and Public Policy

Bartha Maria Knoppers, Marie Hirtle, and Kathleen Cranley Glass
Science 17 December 1999: 2277-2278.
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Perspectives

COMPUTATIONAL ANALYSIS:
Y₂K

Christopher J. Cramer and Jeffrey T. Roberts
Science 17 December 1999: 2281.
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COGNITION:
Enhanced: An Innate Basis for Language?

Dorothy V. M. Bishop
Science 17 December 1999: 2283-2284.
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MOLECULAR BIOLOGY:
Mutant Dyskerin Ends Relationship with Telomerase

Jerry W. Shay and Woodring E. Wright
Science 17 December 1999: 2284-2285.
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MATERIALS SCIENCE:
Imaging Elusive Solute Atoms

M. K. Miller
Science 17 December 1999: 2285-2286.
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DEVICE PHYSICS:
Toward Efficient Smart Pixels

JÜrg P. Kotthaus
Science 17 December 1999: 2286-2287.
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MOLECULAR BIOLOGY:
DNA Methylation de Novo

Adrian Bird
Science 17 December 1999: 2287-2288.
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Tech.Sight

ISOTOPE GEOCHEMISTRY:
New Tools for Isotopic Analysis

Trevor Ireland
Science 17 December 1999: 2289-2290.
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 SOFTWARE:
A Mathematical Swiss Army Knife

John A. Wass
Science 17 December 1999: 2291-2292.
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 SOFTWARE:
Plugging in to Visual Data

Kevin Ahern
Science 17 December 1999: 2293.
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 CELL BIOLOGY:
Sorting on Silicon

Robert Sikorski and Richard Peters
Science 17 December 1999: 2293-2294.
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 NET TIPS:
Y2K or Bust

Richard Peters and Robert Sikorski
Science 17 December 1999: 2294.
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Visions

Technology Transfer

Ruth Kohen
Science 17 December 1999: 2296-2298.
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Appointment as Expert Juror

Mary Ann Krug
Science 17 December 1999: 2298-2299.
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NIH Grant Application

Testing the effects of genetic variations using MINIME technology

Joshua T. Vogelstein, Jacob V. Vogelstein, and Bert Vogelstein
Science 17 December 1999: 2300-2301.
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Research Article

Structure of a Transcribing T7 RNA Polymerase Initiation Complex

Graham M. T. Cheetham and and Thomas A. Steitz
Science 17 December 1999: 2305-2309.
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Reports

Phase-Coherent Amplification of Matter Waves

Mikio Kozuma, Yoichi Suzuki, Yoshio Torii, Toshiaki Sugiura, Takahiro Kuga, E. W. Hagley, and L. Deng
Science 17 December 1999: 2309-2312.
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Exciton Storage in Semiconductor Self-Assembled Quantum Dots

T. Lundstrom, W. Schoenfeld, H. Lee, and P. M. Petroff
Science 17 December 1999: 2312-2314.
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Experimental Tunneling Ratchets

H. Linke, T. E. Humphrey, A. Löfgren, A. O. Sushkov, R. Newbury, R. P. Taylor, and P. Omling
Science 17 December 1999: 2314-2317.
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Three-Dimensional Atomic-Scale Imaging of Impurity Segregation to Line Defects

D. Blavette, E. Cadel, A. Fraczkiewicz, and A. Menand
Science 17 December 1999: 2317-2319.
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Deflection of the Local Interstellar Dust Flow by Solar Radiation Pressure

M. Landgraf, K. Augustsson, E. Grün, and B. Å. S. Gustafson
Science 17 December 1999: 2319-2322.
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Short-Lived Oxygen Diffusion During Hot, Deep-Seated Meteoric Alteration of Anorthosite

Claudia I. Mora, Lee R. Riciputi, and David R. Cole
Science 17 December 1999: 2323-2325.
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Surfactant-Mediated Two-Dimensional Crystallization of Colloidal Crystals

Laurence Ramos, T. C. Lubensky, Nily Dan, Philip Nelson, and D. A. Weitz
Science 17 December 1999: 2325-2328.
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Postnatal Sex Reversal of the Ovaries in Mice Lacking Estrogen Receptors  and  

J. F. Couse, S. Curtis Hewitt, D. O. Bunch, M. Sar, V. R. Walker, B. J. Davis, and K. S. Korach
Science 17 December 1999: 2328-2331.
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Isolation of West Nile Virus from Mosquitoes, Crows, and a Cooper's Hawk in Connecticut

John F. Anderson, Theodore G. Andreadis, Charles R. Vossbrinck, Shirley Tirrell, Edward M. Wakem, Richard A. French, Antonio E. Garmendia, and Herbert J. Van Kruiningen
Science 17 December 1999: 2331-2333.
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Origin of the West Nile Virus Responsible for an Outbreak of Encephalitis in the Northeastern United States

R. S. Lanciotti, J. T. Roehrig, V. Deubel, J. Smith, M. Parker, K. Steele, B. Crise, K. E. Volpe, M. B. Crabtree, J. H. Scherret, R. A. Hall, J. S. MacKenzie, C. B. Cropp, B. Panigrahy, E. Ostlund, B. Schmitt, M. Malkinson, C. Banet, J. Weissman, N. Komar, H. M. Savage, W. Stone, T. McNamara, and D. J. Gubler
Science 17 December 1999: 2333-2337.
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Binding of Transcription Termination Protein Nun to Nascent RNA and Template DNA

Randolph S. Watnick and Max E. Gottesman
Science 17 December 1999: 2337-2339.
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Requirement of Yeast SGS1 and SRS2 Genes for Replication and Transcription

Sung-Keun Lee, Robert E. Johnson, Sung-Lim Yu, Louise Prakash, and Satya Prakash
Science 17 December 1999: 2339-2342.
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Posttranscriptional Gene Silencing in Neurospora by a RecQ DNA Helicase

Carlo Cogoni and Giuseppe Macino
Science 17 December 1999: 2342-2344.
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Evolution of Shape Complementarity and Catalytic Efficiency from a Primordial Antibody Template

Jian Xu, Qiaolin Deng, Jiangang Chen, Kendall N. Houk, Johannes Bartek, Donald Hilvert, and Ian A. Wilson
Science 17 December 1999: 2345-2348.
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Crystal Structure of Thermotoga maritima Ribosome Recycling Factor: A tRNA Mimic

Maria Selmer, Salam Al-Karadaghi, Go Hirokawa, Akira Kaji, and Anders Liljas
Science 17 December 1999: 2349-2352.
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Microglial Activation Resulting from CD40-CD40L Interaction After -Amyloid Stimulation

Jun Tan, Terrence Town, Daniel Paris, Takashi Mori, Zhiming Suo, Fiona Crawford, Mark P. Mattson, Richard A. Flavell, and Michael Mullan
Science 17 December 1999: 2352-2355.
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Cognitive Modularity and Genetic Disorders

S. J. Paterson, J. H. Brown, M. K. Gsödl, M. H. Johnson, and A. Karmiloff-Smith
Science 17 December 1999: 2355-2358.
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Mediation by a CREB Family Transcription Factor of NGF-Dependent Survival of Sympathetic Neurons

Antonella Riccio, Sohyun Ahn, Christopher M. Davenport, Julie A. Blendy, and David D. Ginty
Science 17 December 1999: 2358-2361.
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Use of the Cell Wall Precursor Lipid II by a Pore-Forming Peptide Antibiotic

E. Breukink, I. Wiedemann, C. van Kraaij, O. P. Kuipers, H.-G. Sahl, and B. de Kruijff
Science 17 December 1999: 2361-2364.
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Technical Comments

 Filtering Reveals Form in Temporally Structured Displays

Edward H. Adelson, Hany Farid, Sang-Hun Lee, and Randolph Blake
Science 17 December 1999: 2231.
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