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Cover Figure


COVER The IkB kinase (IKK) complex is responsible for triggering inflammatory responses. However, gene ablation expriments have identified an unexpected function for the IKKa subunit of this complex-control of epidermis formation. Sections of epidermis (~30 mm tall) from normal (top) and IKKa-deficient mice (bottom) stained to visualize nuclei (purple) and nondifferentiated cells (red) reveal the marked expansion of nondifferentiated cells in mutant epidermis. See page 316. [Image: Y. L. Hu]

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Science. ISSN 0036-8075 (print), 1095-9203 (online)