COVER Time-lapse microscopy (over ~1 hour) of human HeLa cells undergoing apoptotic cell death. The green marks a membrane lipid change that occurs during apoptosis, and the red labels DNA after the membrane has lost its integrity, a later apoptotic event. See the Green and Reed Review on p. 1309 and the special section beginning on p. 1301. [Images: J. C. Goldstein, La Jolla Institute for Allergy and Immunology]

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