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High-magnification confocal image of the border between the eye-specific layers in the lateral geniculate nucleus (LGN) of an 11-day-old ferret (image width ~225 micrometers). Retinal ganglion cell axons are labeled with the lipophilic tracers DiI (green; right eye) and DiD (red; left eye); LGN neuron nuclei are stained with Hoechst (blue). The formation of these eye-specific layers depends on interocular competition driven by spontaneous activity present in the retina before vision. See page 2108. [Image: A. Penn and T. Brotz]

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Science. ISSN 0036-8075 (print), 1095-9203 (online)